Anti-depressants Flashcards
give the two first line SSRIs
fluoxetine
citalopram
what SSRI is particularly good post MI
sertraline
give some side effects of SSRIs
GI symptoms
increased risk GI bleed
may be increased agitiation/anxiety immediately after starting
what should you always be aware of in citalopram use
QT prolongation
give some relative CI to SSRI use
- warfarin/heparin use
- aspirin use
- triptans
- MAOIs
give some sedating TCAs
amitriptyline
clomipramine
trazodone
give three ECG changes seen in TCA overdose
sinus tachycardia
widened QRS
prolonged QT
give some features of TCA overdose
dry mouth dilated pupils agitation sinus tachycardia blurred vision
give some less sedating TCAs
nortriptyline
imipramine
give some SE of TCAs
dry mouth constipation postural hypotension blurred vision urinary retention
give three SNRIs
mirtazapine
venlafaxine
duloxetine
how should you switch from citalopram, sertraline or paroxetine to another SSRI
the first should be withdrawn before the alternative started
how should you switch from fluoxetine to another SSRI
withdraw fluoxetine and then leave a gap of 4-7 days before starting the alternative
how should you switch from a SSRI to a TCA
cross taper
give some features of MAOIs
non-selective
irreversible
