Anti Depressants

Question 1

triad of ____1_____, _____2_____, _____3_______, effects is a classic feature of the serotonin syndrome

Answer 1

CAN

cognitive, autonomic, and neuromuscular

Question 2

Serotonin syndrome usually occurs within______________ after the dosage of a serotonin agonist

Answer 2

2 to 24 hours

Question 3

importance of serotonin syndrome in emergency practice is twofold

Answer 3

First, the diagnosis of serotonin syndrome is very challenging because of its nonspecific symptomatology.

Without proper recognition of patients at risk for serotonin syndrome, one may inadvertently precipitate serotonin syndrome by administering serotonergic agents (e.g., meperidine, tramadol, dextromethorphan).

Question 4

The most commonly reported signs and symptoms associated with serotonin syndrome are

Answer 4

altered mental status, hyperthermia, and increased muscle tone

Question 5

Muscle rigidity, when present, is especially prominent in the ________________, which serves as another valuable clinical marker for serotonin syndrome.

Answer 5

lower extremities

Question 6

cornerstone of treating serotonin syndrome is

Answer 6

discontinuing all serotonergic drugs and providing appropriate supportive care

Question 7

Serotonin syndrome  most common cause of death is.

Answer 7

severe hyperthermia

Question 8

is an antihistamine and serotonin antagonist with anticholinergic effects.41-44 It can be used (off-label) for serotonin syndrome, but is only available in PO form.

Answer 8

Cyproheptadine

Question 9

Clinical features of the serotonin syndrome usually resolve within ____________ after the inciting drug is stopped, with an exception being ____________ due to its long half-life and that of the active metabolite.

Answer 9

24 hours

fluoxetine