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Phar 227 > Anti-depressant Notes > Flashcards

Anti-depressant Notes Flashcards

1
Q

What does Psychotropic Mean

A

encompasses antidepressants, antipsychotics and anxiolytics (Anti-anxiety); drugs that act on the mind

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2
Q

What are examples of psychotropic neurotransmitters

A

serotonin, dopamine and GABA

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3
Q

What is depression

A

state of sadness, despair, melancholia that has progressed to a state which disrupts normal living/ functioning

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4
Q

What are 2 different types of depression

A

Bipolar depression, major depression

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5
Q

What does anti-depressants do

A

treat depression and mood disorders

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6
Q

How long does it take for anti-depressants take to work

A

14 days

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7
Q

Can anti-depressants be PRN

A

never

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8
Q

What are different types of anti-depressants

A

TCA, SSRI, MAOI

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9
Q

What does TCA stand for

A

Tricyclic Antidepressants

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10
Q

What are TCAs

A

oldest class of antidepressants

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11
Q

What are some common use for TCAs

A

depression and bedwetting

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12
Q

What is the MOA of TCAs

A

Blocks re-absorption or serotonin and norepinephrine

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13
Q

What does SSRIs stand for

A

Selective serotonin re-uptake inhibitors

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14
Q

What are uses of SSRIs

A

Depression, OCD, panic disorder

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15
Q

What is the Method of action (MOA) of SSRIs

A

blocks re-absorption of serotonin

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16
Q

What does MAOIs stand for

A

Monoamine oxidase inhibitor

17
Q

What are uses of MAOIs

A

depression coupled with anxiety; phobias

18
Q

What is the MAO for MAOI

A

prevents the breakdown of serotonin and norepinephrine by blocking action of enzyme that breaks them down

19
Q

What is a disadvantage of MAOI

A

many interactions with food and drugs, therefore prescribed after SSRIs and TCAs

20
Q

Between TCA SSRI and MAOI which usually prescribed first

A

SSRIs because there is the least amount of side effects

21
Q

What is another name for antipsychotics

A

Neuroleptics

22
Q

What are antipsychotics used for?

A

Treat Psychosis

23
Q

What is the MOA of antipsychotics

A

block dopamine receptors in brain

24
Q

What is Bipolar depression

A

alternating pattern of emotional highs (mania) and lows (depression)

25
Q

What is another name for bipolar drugs

A

antimanic drugs

26
Q

What is anxiety

A

severe anxiety, agitation nervousness.

27
Q

What is a cause of anxiety

A

imbalance of neurotransmitter GABA

28
Q

What is another name for Antianxiety drugs

A

Anxiolytics

Phar 227 (6 decks)

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