Anti-depressant Agents

Question 1

SSRIs

Answer 1

Selective serotonin reuptake inhibitors

Question 2

Approved only for OCD

Answer 2

Fluvoxamine

Question 3

SSRIs six available agents

Answer 3

Fluoxetine
Paroxetine
Sertraline
Fluvoxamine
Citalopram
Estitalopram

Question 4

SSRIs clinical using

Answer 4

Major depression, anxiety, panic, OCD, PTSD, perimenopausal vasomotor symptoms, eating disorders /bulimia /

Question 5

SSRIs toxicity

Answer 5

Half life 15-75 hours, orally, cause sexual dysfunction, risk of serotonin syndrome with MAOIs

Question 6

SNRIs

Answer 6

Serotonin Norepinephrine reuptake inhibitors

Question 7

SNRIs agents

Answer 7

Duloxetine
Venlafaxine
Desvenlafaxine
Levomilnacipran
Milnacipran

Question 8

Three ring structure medication

Answer 8

Duloxetine

Question 9

Bicyclic compounds

Answer 9

Venlafaxine and Desvenlafaxine

Question 10

Approved only for fibromyalgia

Answer 10

Milnacipran

Question 11

Venlafaxine side effects

Answer 11

Hypertension

Question 12

SNRIs toxicity

Answer 12

Anticholinergic, sedation, hypertension

Question 13

TCAs

Answer 13

Tricyclic antidepressants

Question 14

TCAs agents

Answer 14

Imipramine
Desipramine
Clomipramine
Trimipramine
Amytriptyline
Nortriptyline
Protriptyline
Doxepin

Question 15

Only for OCD

Answer 15

Clomipramine

Question 16

TCAs toxicity

Answer 16

Anticholinergic, a-blocking effects, sedation, weight gain, arrhythmias, seizures in overdose

Question 17

5-HT receptors modulators

Answer 17

Nefazodone
Trazodone

Question 18

Hypnosis for

Answer 18

Trazodone

Question 19

Black box warning hepatoxicity 5-HT receptor ?

Answer 19

Nefazodone

Question 20

Vortioxetine

Answer 20

Agonists of the 5-HT1A receptor, treat for cognitive dysfunction associated with depression

Question 21

Tetracyclic agents

Answer 21

Amoxapine
Maprotiline
Mirtazapine

Question 22

Unicyclic aminoketone

Answer 22

Bupropion

Question 23

Bupropion used for

Answer 23

Smoking cessation

Question 24

Mirtazapine used for

Answer 24

Sedation

Question 25

Lowers seizure threshold effects in

Answer 25

Amoxapine and Bupropion

Question 26

Mirtazapine side effects

Answer 26

Sedation and weight gain

Question 27

MAOIs

Answer 27

Monoamine oxidase inhibitors

Question 28

MAOIs agents

Answer 28

Phenelzine Tranylcypromine Selegiline

Question 29

Selegiline used for

Answer 29

Parkinson disease

Question 30

NMDA receptor antagonists

Answer 30

Ketamine Esketamine

Question 31

To produce prolonged delirium “angel dust ”, drugs of abuse

Answer 31

Ketamine / IV route administration /

Question 32

Ketamine used for

Answer 32

Anesthesia

Question 33

Esketamine used for

Answer 33

Refractory depression, acute suicidal ideation

Question 34

FDA panel voted medication

Answer 34

Brexanolone for Postpartum depression

Question 35

Allopregnanolone

Answer 35

Brexanolone IV infusion over 60 hours, excessive sedation toxicity