anti-cholinergics

Question 1

atropine

Answer 1

Competitive inhibition of ACh at nicotinic and muscarinic receptors on target tissues

• topical mydriatic and cycloplegia agent
• IV: treatment of bradycardia and decreases secretions
• contraindicated in glaucoma

Question 2

scopolamine

Answer 2

Competitive inhibition of ACh at nicotinic and muscarinic receptors on target tissues

 - inhibits Ach in CRTZ - CNS depression prominent - good BBB penetration

-treatment for motion sickness and vertigo

Question 3

dicyclomine

Answer 3

Competitive inhibition of ACh at nicotinic and muscarinic receptors on target tissues

-used as intenstinal anti-spasmodic for diarrhea

(Can finally go ride your CYCLE when your IBS is gone)

Question 4

glycopyrrolate

Answer 4

Competitive inhibition of ACh at nicotinic and muscarinic receptors on target tissues

• used to decrease secretions during surgery
• also treats peptic ulcers

Question 5

ipratropium (Atrovent)

Answer 5

Competitive inhibition of ACh at nicotinic and muscarinic receptors on target tissues

-used to treat COPD and asthma via nebulizer

Question 6

tiatroprium (Spiriva)

Answer 6

Competitive inhibition of ACh at nicotinic and muscarinic receptors on target tissues

-used to treat COPD and asthma via nebulizer

Question 7

benztropine (Cogentin)

Answer 7

Competitive inhibition of ACh at nicotinic and muscarinic receptors on target tissues
-BBB penetration

-used to treat Parkinsons

(I forgot where I PARKed by BENZ)

Question 8

tolteradine (Detrol)
Oxybutynin
Solifenacin

Answer 8

Competitive inhibition of ACh at nicotinic and muscarinic receptors on target tissues

-used to reduce bladder spasm and urinary incontinence and cystitis