Anti-asthamtic drugs

Question 1

Anti-asthmatic drugs, count the classes ?

Answer 1

Bronchodilators, corticosteroids, mast cell stabilizers, leukotriene pathway inhibitors, new approaches.

Question 2

Bronchodilators classes ?

Answer 2

Antimuscarinics, Methylxanthines, Sympathomimetics.

Question 3

Antimuscarinics ?

Answer 3

Ipratropium, Tiotropium.

Question 4

Methylxanthines ?

Answer 4

Aminophylline, Cafeine, Theobromine, Theophylline.

Question 5

Sympathomimetics used for Rx asthma ?

Answer 5

• a &b adrenoceptor agonists
• b adrencoceptor angonists
• b 2 selective adrenoceptor agnosits.

Question 6

Sympathomimetics, alpha adrenoceptor agonists ?

Answer 6

Epinephrine, Ephedrine, Isoproterenol.

Question 7

Sympathomimetics, b adrenoceptor agnosits ?

Answer 7

Isoprenaline, Orciprenaline.

Question 8

Sympathomimetics, beta-2 selective adrenoceptor agonists ?

Answer 8

Terbutaline, Salbutamol, Formoterol, Remiterol.

Question 9

Coricosteroids used for Rx of asthma ?

Answer 9

Beclomethasone, Dexamethasone, Hydrocortisone Na Succinate, Methyl Prednisolone, Triamcinolone.

Question 10

Leukotriene pathway inhibitors, its two subclasses ?

Answer 10

• LTD-4 receptors antagonists

- 5-Lipoxygenase inhibitors

Question 11

Leukotriene pathway inhibitors drugs ?

Answer 11

• LTD-4 antagonistis : Montelukast, Zafirlukast.

- 5-Lipoxygenase inhibitors : Zileuton.

Question 12

Mast cell stabilizers / degranulation inhibitors drugs ?

Answer 12

• Disodium Cromoglycate / Cromolyne sodique.
• Nedocromil sodique.
• Ketotifen (H-1 antagonist).

Question 13

What are newer approaches in Rx asthma ?

Answer 13

• Anti IgE monoclonal antibodies : Omalizumab.

- Ca channel blockers : Nifedipine, Verapamil.

Question 14

How are specific Ca channel blockers able to help in asthma ?

Answer 14

Verapamil &Nifidepine are two Ca channel blockers that prove they efficacity in preventing bronchoconstriction caused by exercise, triggers, histamine.