Anti-Arrhythmic Drugs Flashcards by A B | Brainscape

Q

Class 1a & 1c

Main Target

A

Na+ channel blockers

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 1a & 1c

Main action

A

↓conduction rate,

↑refractory period

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 1a & 1c

side effects

A

Can block fast and slow response cells, K+ chan

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 1a & 1c

examples

A

a: quinidine, procainamine
c: flecainide

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 1b

Main Target

A

Na+ channel

blockers

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 1b

Main action

A

↓conduction rate

↑refractory period

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 1b

side effects

A

Can block Ca2+ channels (Class 4 action)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 1b

examples

A

Lidocaine

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 2: Beta blockers

Main Target

A

B-adrenergic receptor blockers

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 2: Beta blockers

Main action

A

Reduces pacing rate and prolongs

refractory period in SA/AV node

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 2: Beta blockers

side effects

A

Block Ca2+

-L, K+, If

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 2: Beta blockers

examples

A

Propranolol

Metoprolol

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 3

Main Target

A

K+ channel

blockers

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 3

Main action

A

Prolong phase 2, and thus refractory period by

↑ Na+ inactivation

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 3

side effects

A

Na+ blocking (amiodarone),

qB-blocking (sotalol)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Class 3

examples

A

Amiodarone

Ibutilide

Q

Class 4

Main Target

A

L-type Ca2+ channel blockers

Q

Class 4

Main action

A

Slows upstroke and depolarization

in nodal cells, and repolarization

Q

Class 4

side effects

A

Can block fast response as well. Slower

upstroke causes fewer K+ to open

Q

Class 4

examples

A

Verapamil

Diltiazem

Q

Adenosine

Main Target

A

A1 adenosine

receptor

Q

Adenosine

Main action

A

↑K+ current, ↓L-type Ca2+ and If

in SA and AV nodes

Q

Adenosine

side effects

A

Intended: causes heart to slow down for a

minute- good emergent

Q

Adenosine

examples

A

Unclassified:
Adenosine,
Digoxin
Isoproterenol