Anthracyclines Flashcards

1
Q

What are the anthracyclines?

A
  • Doxorubicin
  • Daunorubicin
  • Epirubicin
  • Idarubicin
  • Mitoxantrone
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2
Q

What are the mechanism of anthracyclines?

A
  • DNA intercalation
  • Free radical generation
  • Inhibit topoisomerase IIA
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3
Q

What is the max cumulative dose of doxorubicin?

A

550 mg/m2

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