Anthracyclines Flashcards
1
Q
What are the anthracyclines?
A
- Doxorubicin
- Daunorubicin
- Epirubicin
- Idarubicin
- Mitoxantrone
2
Q
What are the mechanism of anthracyclines?
A
- DNA intercalation
- Free radical generation
- Inhibit topoisomerase IIA
3
Q
What is the max cumulative dose of doxorubicin?
A
550 mg/m2