Anthelmintic Resistance

Question 1

What are the main nematodes causing PGE in sheep in UK? (5)

Answer 1

Telodorsagia (Ostertagia) circumcincta, Trichostrongylus spp., Nematodirus battus, Haemonchus contortus, Cooperia spp.

Question 2

What is the main nematode causing PGE in cattle in UK?

Answer 2

Ostertagia ostertagi - dictyocaulus viviparus (lungworm) also important.

Question 3

What are the most important horse worms in the UK? How can they be divided?

Answer 3

The strongyles ‘red worms’ - divided into Large (strongylus vulgaris, equinus, Tridontophorus spp.) and small (Cyathostomins etc.)

Question 4

What is anthelmintic resistance?

Answer 4

When a parasite can tolerate doses of anthelmintics that are usually lethal.

Question 5

What relevant anthelmintic resistance is there in Sheep nematodes?

Answer 5

Multiple resistance. BZ resistance widespread, triple resistance telodorsagia. Lots of triple resistance in NZ, AUS.

Question 6

What relevant anthelmintic resistance is there in Cattle nematodes?

Answer 6

Potentially ML resistant Cooperia spp. - Alot less common than in sheep, mainly underdosing problem.

Question 7

What relevant anthelmintic resistance is there in horses?

Answer 7

BZ resistance now widespread in cyathostomins. Resistance to pyrantel and ML uncommon

Question 8

When doing a faecal egg count reduction test, when is resistance indicated?

Answer 8

If the treatment does not reduce FEC by >95%.

Question 9

Make sure you know SCOPS and COWS guidelines!

Answer 9

Important :)