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FARMA DIGESTIVO > Antespasmódicos > Flashcards

Antespasmódicos Flashcards

1
Q

ANTIESPASMÓDICOS

Familias

A
  • BUTILHIOSCINA/TRIMEBUTINA
  • BROMURO DE PINAVERIO
  • ANTIESPASMÓDICOS/ TX COLÓN IRRITABLE: Clorhidrato de Lidamidina
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2
Q

BUTILHIOSCINA/TRIMEBUTINA
(buscapina)

MoA

A

Anticolinérgico intestinal → disminuye peristaltismo.

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3
Q

BUTILHIOSCINA/TRIMEBUTINA
(buscapina)

Indicaciones generales

A

Tx con espasmos gastrointestinales, biliares y genitourinarios.

Dolor por espasmos GI.

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4
Q

BUTILHIOSCINA/TRIMEBUTINA
(buscapina)

EA

A
  • Taquicardia
  • Sequedad de boca
  • Dishidrosis
  • Trastornos de la acomodación visual
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5
Q

BROMURO DE PINAVERIO

MoA

A

Antagonista de Ca → disminuye peristaltismo.

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6
Q

BROMURO DE PINAVERIO

Indicaciones generales

A

Tx sintomático de dolor tipo cólico
Colon irritable
Colitis
Espasmo intestinal

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7
Q

BROMURO DE PINAVERIO

EA

A
  • Diarrea
  • Náuseas
  • Disfagia
  • Prurito
  • Urticaria
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8
Q

ANTIESPASMÓDICOS/ TX COLÓN IRRITABLE

Fármaco

A

CLORHIDRATO DE LIDAMIDINA

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9
Q

ANTIESPASMÓDICOS/ TX COLÓN IRRITABLE

MoA

A

Estimula receptores 𝛼2 adrenérgicos (Gi):
i) efecto Ca antagonista ii) inhibe AC-AMPc iii) evita la liberación de Ca de depositos intracelulares.

Elimina hiperrreactividad mioenteral, regula motilidad, elimina espasmo.

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10
Q

ANTIESPASMÓDICOS/ TX COLÓN IRRITABLE

Indicaciones generales

A

Manejo de colón irritable, algunos tipos de diarrea, enteroespasmo.

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11
Q

ANTIESPASMÓDICOS/ TX COLÓN IRRITABLE

ADME

A

Absorción rápida en tubo GI.

Pico 1h.

Vida media 3-8h.

Eliminación renal

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12
Q

ANTIESPASMÓDICOS/ TX COLÓN IRRITABLE

EA

A
  • Náuseas
  • Cefalea
  • Constipación
  • Xerostomía
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FARMA DIGESTIVO (6 decks)

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