Antepartum haemorrhage Flashcards

1
Q

Definition of antepartum haemorrhage

A

Bleeding from or into the genital tract during pregnancy that occurs AFTER the point of fatal viability (ie. after 24 weeks)

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2
Q

Causes of antepartum haemorrhage

A

Painless
- Placenta previa*
- Vasa previa
- Lower genital tract tumour/trauma/infection

Painful
- Placental abruption*
- Uterine rupture

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3
Q

What is associated with antepartum haemorrhage?

A

Postpartum haemorrhage

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4
Q

Definition of placenta previa

A

Implantation of placenta overlying completely/partially or proximate to the internal cervical os, at the lower uterine segment after viability

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5
Q

Risk factors of placenta previa

A
  1. Previous caesarean section
  2. Maternal age (extremes of ages)
  3. Prior abortion
  4. Multiparity (2-4)
    - High risk if 5 or more
    - Due to a change in shape and size of uterus = More space for placenta to implant in the LUS
  5. Smoking
  6. Previous placental abruption/ placenta praevia/ uterine surgery
  7. Use of assisted reproductive technologies
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6
Q

Signs & symptoms of placenta previa

A
  1. PAINLESS VAGINAL BLEEDING***
    - usually in 3rd trimester
    - can be recurrent
    - a/w irritable uterus (ie uterine contractions) or onset of labour
  2. Malpresentation: transverse or breech
  3. Presenting part high - deviated from midline
  4. Asymptomatic
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7
Q

Diagnosis for placenta previa

A

Transvaginal U/S
- If low-lying placenta is diagnosed in FA scan, repeat scan is done at 32 and 36 weeks for confirmation

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8
Q

Complications of placenta previa

A

Maternal
- Mortality & morbidity
- Post partum haemorrhage
- Placenta accreta/percreta
- Caesarian complications -> high bleeding risk
- Blood transfusion
- Recurrence

Fetal
- Mortality & morbidity
- Pre-term delivery
- IUGR

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9
Q

Physical examinations for APH

A

Assess maternal and fetal well-being and determine the cause of APH

Maternal well-being:
Regular vitals assessment TRO hypovolemic shock
Presence of HTN warrants excluding pre-eclampsia

Fetal well-being:
Continuous CTG monitoring to trace foetal heart beat for signs of fetal distress

Abdomen:
SFH
Palpate for contractions and woody hard uterus for placenta abruptio
Determine fetal lie and presentation

Bedside U/S:
Exclude placenta and vasa previa, retroplacental haemorrhage and confirm fetal presentation

Speculum examination:
Amount of blood in vagina, presence of active bleeding, appearance of cervix to assess dilatation

Vaginal examination:
I will NOT perform a vaginal exam if placenta and vasa previa have NOT been excluded

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10
Q

Expected PE findings for placental previa

A

Non-tender uterus
Transverse lie or breech malposition
Presenting part high

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11
Q

Investigations for APH

A

Bloods
1. FBC
- Hb for anemia and platelets for thrombocytopenia
2. GXM (at least 4 units)
- Blood transfusion, anti-D immunoglobulin if RH-neg
3. DIC screen (PT/PTT, INR, Plt, Fibrinogen, D-dimers)
- Prolongation of PT/PTT and fibrinogen
- Fibrinogen < 2 is diagnostic of DIC in pregnancy
4. RP, LFT
- Pre-op bloods

*With every episode of bleed in APH, Rhesus -ve woman needs Kleihauer Betke test + Prophylactic RhoGAM (Anti-D Ig)

Imaging
TVUS
- Confirm location of placenta if unbooked case of placenta previa
- Retroplacental haemorrhage
- Confirm fetal presentation

Foetal
Continuous cardiotocography monitoring to trace foetal heart beat for signs of fetal distress

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12
Q

Management of ACUTE placenta previa

A

Emergent management
1. Activate obstetric code –consultant obstetrician, anesthetist, senior midwife and neonatologist
2. ABCs
3. Continuous maternal vital signs monitoring, Continuous cardiotocography monitoring to trace foetal heart beat for signs of fetal distress
4. Keep NBM
5. IDC for hourly I/O charting
6. Pad charting
7. Insert large bore IV line: give IV fluids - crystalloids and colloids as needed
8. Draw blood to send off for investigations
9. Call blood bank for packed red cell and blood product transfusion
10. Monitor bleeding
- If ongoing bleed, get informed consent and prep for CAESAREAN section
- If bleed settles and CTG normal, observe patient in labour ward (McAfee regimen) and aim to delay to term (37 weeks)
-> IM dexamethasone for fetal lung maturity if preterm and delivery not immediately required
11. Postpartum haemorrhage prophylaxis post delivery

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13
Q

Management of ‘placenta previa’
(Antenatal - low lying placenta)

A
  1. No intervention required
    - Most placenta would ‘migrate’ upwards as lower uterine segment forms (it does not actually move upwards bc it is stuck to the wall, it is just that the LUS grows longer in a sense)
  2. Advice given:
    - Admit with any antepartum haemorrhage
    - Avoid sexual intercourse
  3. Avoid digital cervical examination
    - Can still do speculum exam to assess cervical dilatation or lower genital tract cause of APH
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14
Q

Indications for immediate delivery (APH)

A

APH after 37 weeks
Major haemorrhage preterm posing threat to mother or fetus

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15
Q

Management of STABLE placenta previa

A

Expectant management following McAfee regimen to delay delivery until term (37 weeks)
1. Stay in fully equipped maternity unit from time of initial diagnosis till delivery
2. Regular maternal vital signs monitoring, regular cardiotocography monitoring to trace foetal heart beat for signs of fetal distress
3. Complete bedrest
4. Stool softeners + high fiber diets to prevent constipation and straining
5. Periodic assessment of maternal Hct
- Prophylactic transfusions to maintain maternal Hct >30% in anticipation of future blood loss
6. Ferrous gluconate + Vit C to improve intestinal Fe absorption
7. Pad chart - Monitor bleed
8. IM dexamethasone for fetal lung maturity if preterm and delivery not immediately required
9.Kleihauer-Betke test and prophylactic Anti-D Ig for Rh -ve women
- Only if they bled
- Readministration not needed if delivery or rebleeding occurs within 3 weeks
10. Serial U/S every 2-4 weeks to assess placental location, fetal growth, AFI
11. Tocolytics if contraction are present but delivery is not needed (mother + fetus safe)
12. Aim to deliver at 37 weeks GA
13. Delivery via elective lower segment caesarean section

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16
Q

Choice of delivery in placenta previa

A

Caesarean section!!! (Elective > emergent)
- Placenta praevia major
- Continued vaginal bleeding
- Abnormal lie

Timing
~38-39 weeks
- Earlier if bleeding doesn’t settle during expectant management

Preparation
- GXM 2 units of blood

17
Q

For placenta previa: If there is bleeding during caesarian section, where is the source of the bleed?

A

Atonic lower segment and venous sinuses bleed
- Failure of uterus to contract adequately following delivery -> NO compression of blood vessels and slowing of blood flow

Placenta densely adherent (accreta/percreta)

18
Q

For placenta previa: If there is bleeding during caesarian section, how to manage the bleed?

A
  • DRUGS: oxytocics, prostaglandin analogues
  • Bimanual compression, packing
  • Oversewing bleeding sinuses with atraumatic sutures, B-Lynch suture, uterine/internal iliac artery ligation
  • Caesarean hysterectomy
19
Q

What is Kleihauer-Betke Test and when is it indicated?

A

Indicated when mother is Rh -ve and has APH!!!

  • Blood test collected from mom to quantify the amount of fetal blood found in the maternal circulation
  • Used to assess the severity of fetomaternal hemorrhage (FMH)
  • Use to assess dose of prophylactic anti-D immunoglobulin for pregnant Rh-negative moms
  • Based on the principle that fetal hemoglobin is more resistant to acid elution than adult hemoglobin
  • > 5 ml of fetal blood in maternal circulation can be detected
20
Q

Pertinent history taking points for APH

A
  • Initiation factors – trauma, coitus Amount and nature of bleed
  • Associated abdominal pain or uterine contractions
  • Hx of ruptured membranes or previous PV bleeds (APH/threatened abortion)
  • Confirmed gestational age
  • Information of placental site/fetus from previous scans**
21
Q

Grading of placenta previa

A

Placenta previa minor (low-lying placenta)
Grade I: Placental edge within 2-3cm of internal cervical os
Grade II: Placental edge reaches cervical os but does not cover it

Placenta previa major
Grade III: Placenta covers part of cervical os
Grade IV: Completely covers cervical os

22
Q

When can NVD (instead of c-sec) be considered in placenta previa?

A

If placental edge >2.5cm away from os, can still try NVD
- Ensure that pt has never bled before