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Board/First Aid > ANS Pharm > Flashcards

ANS Pharm Flashcards

1
Q

Muscarinic Receptors on the heart
on the CNS
everything else

A

Heart: M2, Gi
CNS: M1, Gq (and enterics)
Everything Else: M3, Gq

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2
Q

Bethanechol

A

Muscarinic Agonist

  • ileus
  • urinary retention
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3
Q

Methacholine

A

Muscarinic Agonist

-bronchial hyperreactivity

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4
Q

Pilocarpine

A

Muscarinic Agonist

  • glaucoma
  • xerostomia
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5
Q

Edrophonium

A

AChase inhibitor

-diagnose myasthenia gravis

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6
Q

Physostigmine

A

AChase inhibitor

  • glaucoma
  • atropine overdose
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7
Q

Neostigmine

A

AChase inhibitor

-ileus, urinary retention, myasthenia gravis

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8
Q

Donepazil/Tacrine

A

AChase inhibitor

-Alzheimer Disease

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9
Q

Pralidoxime

A

Regenerates AChase

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10
Q

Atropine

A

Muscarinic Antagonist

-SANS effects

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11
Q

Tropicamide

A

Muscarinic Antagonist

-topical pupil dilator

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12
Q

Ipratropium

A

Muscarinic Antagonist

-asthma and COPD

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13
Q

Scopolamine

A

Muscarinic Antagonist

-motion sickness

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14
Q

Benztropine/Trihexyphenidyl

A

Muscarinic Antagonist

-Parkinsonism

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15
Q

Location of D1 receptors

A

Renal Vessels

-vasodilation

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16
Q

Phenylephrine

A

Alpha-1 agonist

-nasal decongestant

17
Q

Methoxamine

A

Alpha-1 agonist

-paroxysmal atrial tachycardia

18
Q

Clonidine

A

Alpha-2 agonist

-moderate HTN

19
Q

Methyldopa

A

Alpha-2 agonist

-pregnancy HTN

20
Q

Isoproterenol

A

Beta agonist

-bronchospasm, heart block

21
Q

Dobutamine

A

Beta-1 agonist

-congestive heart failure

22
Q

Salmeterol

A

Beta-2 agonist

  • long term prophylaxis for asthma
  • tremors
23
Q

Albuterol

A

Beta-2 agonist

-asthma attack

24
Q

Ritodrine

A

Beta-2 agonist

-premature labor (decreased uterine tone)

25
Q

Oxybutynin

A

Muscarinic Antagonist

-reduce urinary urgency and bladder spasms (mainly in mild cystitis)

26
Q

Amphetamine

A

Induces central release of DA, NE, 5HT

-used in narcolepsy, ADHD

27
Q

Ephedrine

A

Nasal decongestant that releases stored catecholamines

28
Q

Phentolamine

A

Alpha Antagonist

-given to patients on MAOIs who eat tyramine containing food

29
Q

Phenoxybenzamine

toxicity

A

Alpha Antogonist

  • Pheochromocytoma (used to reduce catecholamine levels before surgery)
  • Tox: orthostatic hypotension, reflex tach
30
Q

Prazosin, Terazosin, Doxazosin

toxicity

A

Alpha-1 Blockers

  • HTN, urinary retention, BPH
  • Tox: 1st dose orthostatic hypotension, headaches, dizziness
31
Q

Mirtazapine

A

Alpha-2 blocker

-depression

32
Q

Name the Beta-1 antagonists (5)

A 
Acebultolol
Betaxolol
Esmolol
Atenolol
Metoprolol
33
Q

Name the 4 non-selective Beta blockers

A

Propranolol
Timolol
Nadolol
Pindolol

34
Q

Name the two partial beta agonists

A

Pindolol

Acebutolol

35
Q

Name the 2 beta blockers that also have alpha agonist activity

A

Carvedilol

Labetolol

Board/First Aid (6 decks)

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