ANS drugs - cholinergics Flashcards
1
Q
cholinergic agonists
A
-stimulate the parasympathetic nervous system
-mimic the parasympathetic neurotransmitter-acetylcholine
-
2
Q
cholinergic drugs indications
A
- MG
- urinary retention
- glaucoma
- n/v
- Alzheimer’s
3
Q
muscarinic receptors
A
stimulate smooth muscle and slow the HR
4
Q
nicotinic receptors
A
affect the skeletal muscles
5
Q
cholinergic agonists effects
A
- stimulate bladder & GI tone
- miosis
- increase neuromuscular transmission
- decrease HR & BP
- increase salivary, GI, and bronchial glandular secretions (wet)
6
Q
cholinergic drug names
A
- prostigmine (neostigmine)
- bethanechol (urecholine)
- reglan (metoclopramide)
- donepezil (aricept)
- endrophonium (tonsilon)
- pyridostigmine (mestinon)
7
Q
prostigmine (neostigmine)
A
MG
8
Q
bethanechol (urecholine)
A
stimulate bladder to release urine
9
Q
donepezil (aricept)
A
- used for Alzheimers
- causes insomnia, but qday only
10
Q
endrophonium (tonsilon)
A
diagnostic for MG
11
Q
pyridostigmine (mestinon)
A
MG
12
Q
cholinergic crisis
A
- salivation
- lacrimation
- urination
- defacation
- antidote=atropine sulfate
13
Q
anticholinergic drugs
A
- inhibit the action of acteylcholine by occupying acetylcholine receptors
- have opposite response of cholinergic drugs
14
Q
anticholinergic indications
A
- GI/GU disorders
- Parkinson’s
- motion sickness
- assist in preventing s/e of other drugs
15
Q
anticholinergic names
A
- Atropine
- oxybutynin (ditropan)
- scopolamine (transferm-scop)
- trihexyphenidyl (artane)
- benztropine (cogentin)
