ANS and Hypothalamus Flashcards

1
Q

function of the ANS

the 2 efferent divisions

A

maintains homeostasis

(regulate digestive/urinary systems, visceral fx)

involuntary

Sympathetic (SNS) – “fight or flight”
Parasympathetic (PNS) – “rest and digest”

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2
Q

what are the three afferents that stimulate ANS responses

A
  1. General sensations – such as pain, temp., and touch
  2. Special senses – such as vision or hearing
  3. Visceral afferents – sensation from organs communicated via solitary nucleus tract and visceral afferent nucleus in SC
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3
Q

which type of muscle receives NO innervation from the ANS

A

Skeletal muscle receives no direct innervation from the ANS

The ANS does innervate smooth muscle, cardiac muscle, glands, and organs

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4
Q

preganglionic and postganglionic neurons for SNS

A

Preganglionic – lateral horn of T1 to L2/L3

Postganglionic:

  1. could send signal to sympathetic chains (release Ach)
  2. signal to specialized postganglionic neurons (closer to target organs also release Ach)
    * ** if an axon makes it all the way to the target organ, it will release NOREPINEPHRINE
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5
Q

preganglionic and postganglionic neurons for PNS

A

Preganglionic – CN nuclei 3, 7, 9, 10 and lateral horn of S2-S4

Postganglionic - close to target organs, release Ach along the way

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6
Q

which system uses only ACH as the neurotransmitter and which also uses epinephrine and norepinephrine

A

Parasympathetic – uses only ACH

Sympathetic – uses ACH, epinephrine, and norepinephrine

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7
Q

what is unusual regarding the adrena medulla in the SNS

A
Only has one afferent 
Does not have two chains 
Releases epinephrine when stimulated 
This, in turn, causes the fight or flight cascading release of hormones
(fight/flight in the kidney)
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8
Q

which three structures have only SNS and no PNS innervation

A
  1. Sweat glands
  2. Piloerector muscles
  3. Peripheral blood vessels in skin
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9
Q

CN nuclei containing PNS preganglionic neurons

A
Edinger Westphal nucleus 
- Located in the midbrain 
- Related to CN III
Lacrimal and superior 
salivatory nuclei 
- Located in the pons
- Related to CN VII
Inferior salivatory nucleus 
- Located in the medulla 
- Related to CN IX
Dorsal vagal nucleus 
- Located in the medulla 
- Related to CN X
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10
Q

what is referred pain and why do we get it

A

Pain felt at a site distant to the cause of pain
Has to do with visceral afferents
- caused by the convergence of somatosensory & visceral afferents on a single pain tract cell

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11
Q

what causes horner’s syndrome? what are the s/s

A

Cause: a lesion in the descending sympathetic innervation to the face
S/S:
- Pupillary constriction (myosis)
- Dry face (***no sweat), warm, and very red
- Ptosis
- PICA also affected (seen as part of lateral medullary/Wallenburg’s syndrome)

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12
Q

what causes autonomic dysreflexia? what are the s/s

A

Cause: lesion in upper thoracic or cervical spinal cord which interrupts asc pathways (SC and brain not communicating)
S/S:
- Severe hypertension
- **Sweating above the level of the lesion with flushing of the skin
- Pounding headache
- Blurred vision
- Nausea
- Bradycardia
- Pilomotor erections
Note: the above s/s may occur in unison or any combination, but may not all occur at once

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13
Q

what should a clinician do if they recognize autonomic dysreflexia

A

Remove stimulus if possible
Stop all activity
Place patient upright
Call 911

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14
Q

general organization of the hypothalamus

A

Regions of the hypothalamus are organized:
Anterior to posterior
Midline to lateral

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15
Q

nuclei/areas tied to the ANS

- anterior hypothalamus

A

Preoptic nuclei – thermoregulation

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16
Q

nuclei/areas tied to the ANS

- middle hypothalamus

A

Paraventricular – related to hormones such as oxytocin and vasopressin, also direct autonomic control including urination

Dorsomedial – feeding, drinking, and body weight regulation

17
Q

nuclei/areas tied to the ANS

- lateral hypothalamus

A

Various functions including arousal and food intake

18
Q

which hypothalamic and brainstem areas project to the spinal cord lateral horn and why is this important when there is a high thoracic or cervical SCI

A
  • both the hypothalamus and BS areas have descending inputs the ANS spinal cord
  • spinal cord injuries can disrupt that control
  • a SCI at this level would interrupt descending hypothalamic regulation, thus causing autonomic dysreflexia
19
Q

alpha and beta adrenergic receptors of norepinephrine

A

alpha: receive norepinephrine, EXCITES a target tissue EXCEPT in GI where they INHIBIT
beta: receive norepinephrine, they INHIBIT, EXCEPT in the heart it is EXCITED

20
Q

ANS reflexes (2)

A
  • baroreceptor reflex (BP)

- micturition (filling/emptying bladder)