ANS Flashcards

1
Q

Botulinum toxin

A

Inhibits release of acetylcholine from presynaptic neuron by inhibiting calcium channel

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2
Q

Which type of botulinum toxin is used as drugs

A

Type A toxin»»type B

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3
Q

Type A botulinum toxin e.g.

A

Onabotulinum toxin A(botox),
Abobotulinum toxin A(dysport),
Incobotulinum toxin A

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4
Q

Antagonist of Nn receptors

A

Ganglionic blockers
E.g- hexamethoneum
Trimethaphan

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5
Q

Nm receptors antagonist

A

Non depolarising muscle relaxant (NDMR)
E.g - tubo curare
Atra curium
Ve curonium

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6
Q

Predominant muscarinic receptor in brain

A

M1

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7
Q

Drug for alzheimer and why

A

Cholinergic drugs—> inc. Ach —-> acts on hippocampus
Ach–> inc. memory and cognition

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8
Q

Cholinergic or anti cholinergic drugs in parkinson’s disease,why

A

Anti cholinergic drugs.

Ach —> acts on basal ganglia –>
dec. Dopamine

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9
Q

M1 receptor agonist

A

OXOTREMORINE (inc. HCl)

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10
Q

M1 receptor antagonist

A

PIREN ZEPINE,
TELEN ZEPINE,

dec. HCl , therefore given in PEPTIC ULCER

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11
Q

Which muscarinic receptor antagonist are given in PEPTIC ULCER and why

A

M1 receptor antagonist,
PIREN ZEPINE
TELEN ZEPINE,

dec. HCl

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12
Q

M2 receptor is located in

A

Heart

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13
Q

M2 receptor agonist

A

METH CHOLINE

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14
Q

M3 receptor function

A

Vasodilation - blood vessels
Contraction -smooth muscle

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15
Q

M3 receptor agonist

A

BETHAN ECOL
inc. smooth muscle contraction

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16
Q

M3 receptor antagonist

A

SOLE FENA CIN,
DARE FENA CIN,

relaxes smooth muscle

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17
Q

Direct acting cholinergic drugs - esters e.g.

A

chol in all

A- Acetylcholine
B- BETHANE CHOL
C- CARBA CHOL
M- METHA CHOLINE

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18
Q

Specific Aplha 1 agonist

A

PHENYL EPHRINE

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19
Q

Specific Aplha 2 agonist

A

COLNIDINE

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20
Q

Specific Aplha 1 antagonist

A

PRA ZO SIN

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21
Q

Specific Aplha 2 antagonist

A

YO HIM BINE

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22
Q

Non specific Alpha agonist

A

EPINEPHRINE,
NOR EPINEPHRINE

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23
Q

Non specific Alpha antagonist

A

PHENOXY BENZAMINE,
PHENYO LAMINE

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24
Q

Specific beta 1 agonist

A

DO BUTAMINE

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25
Q

Specific beta 1 antagonist

A

ATENO LOL
METO PRO LOL

26
Q

Specific beta 2 agonist

A

SAL BUTA MOL,
RITO DRINE

27
Q

Specific beta 2 antagonist

A

BUTAX AMINE

28
Q

Specific beta 3 agonist

A

MIRA BEGRON

29
Q

Non specific beta agonist

A

ISO PRENA LIN

30
Q

Non specific beta antagonist

A

PRO PRANO LOL

31
Q

DOC cardiogenic shock

A

Nor epinephrine ,
Dopamine

32
Q

DOC in vasodilatory shock

A

Nor epinephrine ,
Dopamine

33
Q

Epinephrine acts on which sympathetic receptors

A

Alpha 1, Alpha 2,
Beta 1, Beta 3

34
Q

Epinephrine is used in

A

ABCD
A- Anaphylaxis
B- Brittle asthma
C- Cardiac Arrest
D- During/along with local anaesthetic

35
Q

Epinephrine acts on which sympathetic receptors

A

Alpha 1,2,
Beta 1,2,3

36
Q

Dopamine acts on which sympathetic receptors

A

D1-D2,
Alpha 1 2
Beta 1-3

37
Q

DOC in oliguria/acute renal failure

A

DOPAMINE (Low dose 1-2 micro g/kg/min.
coz acts on D1

38
Q

Phenylephrine

A

1- selective Alpha 1 agonist
2-DOC in hypotension in spinal anesthesia
3- DOC in hypotension in aortic dissection

39
Q

MIDODRINE

A

DOC in postural hypotension

40
Q

DOC in postural hypotension

A

MI DO DRINE

41
Q

DOC in hypotension in spinal anesthesia

A

PHENYL EPHRINE

42
Q

DOC in hypotension in aortic dissection

A

PHENYL EPHRINE

43
Q

Topical nasal drops

A

OXY META ZOLINE,
XYLO META ZOLINE,
NAPHA ZOLINE,

PHENYLEPHRINE

44
Q

Oral nasal decongestants

A

Phenylephrine
Ephedrine
Pseudophedrine

45
Q

Tocolytics/ uterine relaxant drugs

A

RITO DRINE
ISO XEU PRINE

46
Q

Drug used in treatment of overactive bladder

A

MIRA BE GRON,
Beta 3 agonist

47
Q

DOC in narcolepsy

A

MODA FINIL,

TIPRO LISANT,
SOLRI AM FETOL,

48
Q

DOC in obstructive sleep apnea

49
Q

DOC in adhd

A

METHYL PHENI DATE

50
Q

Drug used to increase attention span

A

METHYL PHENI DATE

51
Q

DOC in hypotension in pregnancy

52
Q

Alpha 2a agonist

A

CD TAG
C- Clonidine
D- Dex mede to midine
T- Ti zani dine
A- Alpha methyl dopa
G- Guanfacine,Guanbenz

53
Q

DOC in:
1- pregnancy induced hypertension
2- chronic htn in pregnancy

A

1- Labetalol
2- Alpha methyl dopa

54
Q

Non selective Alpha blockers,non competative + irreversible blockers

A

PHEN OXY BENZAMINE

55
Q

Non selective Alpha blockers, competative+ reversible blockers

A

PHEN TO LAMINE
TOLA ZO LINE
CHLOR PRO MAZINE
ERGO TAMINE

56
Q

DOC in pheochromocytoma

A

PHENOXY BENZAMINE
(non selective Alpha blockers)

57
Q

Alpha 1 A blockers

A

Prazosin,
Terazosin,
Doxazosin,
Alfuzosin,
(all ends with zosin)

58
Q

DOC in postural hypotension

A

MI DO DRINE

59
Q

BPH +HTN

60
Q

DOC for glaucoma

A

PGF2 alpha