ankylosing Spondylitis LP 5 Flashcards
what is ankylosing spondylitis?
progressive condition of the axial skeleton presenting as pain and stiffness in the spine leading to bony ankylosis of the sacroiliac and spinal joints
where on the axial skeleton does inflammation occur?
where ligaments insert onto bone rather then synovium
can ankylosing spondylitis lead to synovitis?
yes
who is more likely to have severe cases of spondylitis?
men
what is the most common type of spondylitis?
marie-stumpell type
what is the Marie stumpell ankylosing spondylitis?
begins in the sacroiliac and in the lumbar region to eventually progress up the spine
is muscle wasting and neurological symptoms common with Marie stumpell ankylosing spondylitis?
yes
muscle wasting can be prevented
which type of ankylosing spondylitis is rare?
bechterew type
what is bechterew ankylosing spondylitis?
begins in the cervical spine and spreads downwards
where are women more likely to develop ankylosing spondylitis first?
in the cervical spine
what causes ankylosing spondylitis?
idiopathic ( 30 times more common in those with a family history )
is ankylosing spondylitis autoimmune ?
yes
what genetic marker is seen in clients with ankylosing spondylitis?
HLA-B27
what’s the most common presentation of ankylosing spondylitis?
inflammation, periosteum and synovium of the SI joint or lumbar spine
what does ossification of the annuls fibrosis lead too?
bony ridges at the periphery of the intervertebral joints
