Anino Acid Absorption

Question 1

What are the end products of protein digestion ?

Answer 1

Free amino acids, dipeptides, tripeptides and oligopeptides

Question 2

Free amino acids are absorbed from the __ and ___ while oligopeptides are absorbed from the __ and ___

Answer 2

1) ileum and distal jejunum
2) duodenum and proximal jejunum

Question 3

__ are the least rapidly absorbed Amino acids

Answer 3

Dicarboxylic amino acids

Question 4

__ is the mechanism by which amino acids are absorbed

Answer 4

Ion gradient hypothesis (a.k.a sodium dependent carrier mediated process)

Question 5

Y-glutamyl cycle (mesiner’s cycle) involves…

Answer 5

The transfer of glutamyl group from glutathione and the subsequent regeneration of glutathione

Question 6

___ is the key enzyme of the Y-glutamyl cycle

Answer 6

Y-glutamyl transpeptidase

Question 7

The second reaction (release of 5-oxo-proline) of meister’s cycle is catalyzed by

Answer 7

Y-glutamyl cyclotransferase

Question 8

What is the third reaction of meister’s cycle ?

Answer 8

5-oxoproline is converted to glutamate by 5-oxo-prolinase in the presence of ATP

Question 9

L-glutamyl-cysteine combines with glycine to regenerate glutathione in a reaction catalyzed by __

Answer 9

Glutathione synthetase