Animal Patho 1 Flashcards
First PP
What is Pathology?
The study of characteristic, causes and effects of disease observed in the structure and function of the body
Gross Patho
what we see and visualize
Histopathology
tissues and under the microscope
Clinical pathology
give blood, pee in cup, tests
Etiology
Provides a precise cause of the disease
Bacteria> Lesion > Clinical Signs
Pathogenesis
The developmental process of a disease involves the sequence of events from initial cellular injury to the full manifestation of the disease, including identifying the causal agent, host response, and underlying disease processes.
Response to Disease
Cell Death
Necrosis
doesn’t matter which if cells organelles are affected cell will die
coagulation cell death
where the cell components collapse into an amorphous mass
Lytic Death
where there is an intake of water and the cells rupture.
What can Death of cells be caused by
Ischemia
Burns/trauma
Chemicals
Microorganisms- fungus
Toxins- poisin
Inflammation
Acute and Chronic
Complex progression of vascular changes
that develops in response to tissue injury
How does Inflammation Happen
Endothelium of the capillaries leak into the interstitial space- trying to dillute out the splinter in your fringer
Dilution, sequestration, and destruction of the causal agent- send white blood cells to eat it up
Plasma proteins include: albumin, fibrinogen, globulin
Blood Cells include: neutrophils, monocytes, mast cells, platelets, macrophages
what are the 3 levels of wound healing
Primary Intention
Secondary Intention
Tertiary Intention
What is Primary Intention Wound Healing- fresh wound or lacertian
Surgical wound- fresh clean, open up and then sew back togther
Laceration that is less than 6 hours old and not infected
Wound edges are brought together
Second Intention Healing
Wound is deeper or older, clean wound, delayed healing of skin
Tertiary Healing
Used for contaminated wound, something that gest smashed/ very contaminated
Suture surgically after clean (4-5) days
Granulation Tissue
In horses you have to make sure the granulation tissue does not extend over the wound edges. Trim them back to allow epithelialization
Granaltion tissue keeps going, skin cant grow over that, so you have to cut it off
What are Congenital defects
Genetic
Teratogenic agents- causes development of physical defects in embryo/fetus- could be medicine or plants
Need to know trauma, causes of Disease
Electrical
Solar /UV
Thermal (Heat or Cold)
Mechanical (Contusion, Abrasion, Laceration, Compression)
Neuropathies
