Angina And Peripheral Vascular Diseases Flashcards

1
Q

What are the symptoms of stable angina

A

No pain at rest
Pain with certain level of exertion - can be worse with cold weather/emotions
Pain relieved by rest

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2
Q

What are the signs of stable angina

A
Often none
Occasionally hyperdynamic circulation:
Anaemia
Hyperthyroidism
Hypovolemia
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3
Q

What investigations should be carried out in patients with angina

A

ECG - resting and during exercise
Angiography
Echocardiography
Radioisotope studies

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4
Q

What is angiography

A

Using a dye to look at the patency of arteries

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5
Q

What is echocardiography

A

Using ultrasound to look at function of heart valves and ventricles

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6
Q

What are radioisotope studies used for and why are they useful

A

Looks at the proportion of blood ejected from the left ventricle CNS
Useful to see how much residual function is present

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7
Q

Why is an ECG during exercise useful

A

Test ischaemia of the heart in real time
Allows changes to bee seen and stopped at the reversible stage
ST depression increases as ischaemia increases

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7
Q

In what ways can angina be treated

A

Reduce oxygen demands of the heart

Increase oxygen delivery to the tissues

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8
Q

How can the oxygen demands of the heart be reduced

A
Reduce afterload (blood pressure)
Reduce preload (venous filling pressure)
Correct mechanical issues such as failing heart valves or septal defects
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9
Q

How can oxygen delivery to the tissues be increased

A

Dilate blocked or narrowed vessels - angioplasty

Bypass blocked or narrowed vessels - Coronary Artery Bypass Graftine (CABG)

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10
Q

Describe non-drug therapy in angina

A

Explanation of illness - patient may require understanding of what triggers their angina and can manage their lifestyle to avoid these situations
Modify risk factors - stop smoking, graded exercise programme, improve diet and control cholesterol

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11
Q

Which drugs can be used to treat angina

A

Aspirin - reduce MI risk
Treat hypertension - Diuretics, Ca2+ blockers, ACE inhibitors and beta blockers
Emergency treatment - GTN spray
Long term prevention - Isosorbide mononitrate

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12
Q

What surgical therapies can be carried out on patients with angina

A

CAGB

Angioplasty and Stent

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13
Q

Describe a Coronary Artery Bypass Graft

A

Veins taken from leg and reversed to prevent occlusion of blood flow by the valves
Internal mammary artery diverted to the coronary artery supply
Only possible if blockage is close to origin of the artery

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14
Q

Describe angioplasty and stunting

A

Cannula put in femoral artery in leg or radial or brachial in arm then passed through vascular system to the narrowing
Balloon is blown up which squashes the plaque then stent will click into position
When balloon is removed, the stent if left holding open the artery

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15
Q

What prevents platelet adhesion to a stent

A

Chemicals coating the stent to inhibit platelet adhesion

Patient is usually on 2 anti-platelet drugs

16
Q

What is peripheral vascular disease

A

Angina of the tissues - usually in the lower limb

Atheroma formed in femoral or popliteal vessels

17
Q

What are the symptoms of PVD

A

Pain on exercise - claudication

Pain relieved with rest - claudication distance

18
Q

What are the signs of PVD

A

Poor wound healing due to reduced oxygen delivery

May lead to tissue necrosis and gangrene