Aneuploidy

Question 1

What is non disjunction in anaphase 1&2

Answer 1

1- failure of homologous chromosome to seperate

2- failure of sister chromatids to separate

Question 2

Anaphase lag

Answer 2

Chromosomal loss via micronucleud
Daughter cell deficiency of chromosome

Question 3

Disomic and nullisomic gamete

Answer 3

Disomic- 2 chromatids in one gamete
Null- 0 chromatids
Normal monosomic - 1 chromatid

Question 4

1st & 2nd polar

Answer 4

1- affter meiosis 1
2- after meiosis 2 , after fertilization when sperm penetrates egg

Question 5

21:21 fusion

Answer 5

Roberstinian translocation of 2 , 21 chromosomes
At meiosis cant form normal gametes

Question 6

Reciprocal translocation segregation

Answer 6

2:2 segration / 2 chromosomes to 1 gamete
Normal, balanced or unbalanced

3:1 3 chr to 1 gamete

Always unbalanced