Anesthesia - Respiratory Patients Flashcards
acepromazine - respiratory effects
minimal to none
how do anesthetic agents affect the respiratory system
- hypoventilation
- V/Q mismatch from atelectasis + depression of HPV (leading to hypooxygenation)
- airway dilation
- decreased secretions
dexmedetomidine - respiratory effects
minimal BUT potentiates the effects of other drugs
benzodiazepines - respiratory effects
minimal to none
opioids - respiratory effects
respiratory depression
anticholinergics - respiratory effects
bronchodilation (increased dead space)
decreased/thickened secretions
induction agents - respiratory effects
hypoventilation
propofol > alfaxalone > ketamine, etomidate
may cause apnea
inhalants - respiratory effects
hypoventilation
decreased response to hypoxemia
bronchodilation
decreased mucociliary clearance
decreased RR
ventilation and oxygenation measures to monitor
- minute ventilation
- PCO2
- PO2
how to measure minute ventilation
MV = RR x TV
tidal volume - measured with Wright respirometer
normal minute ventilation, RR, and TV
MV: 150-250 mL/kg/min
RR: 15-20 bpm
TV: 10-20 mL/kg
what does PCO2 measure
adequacy of alveolar ventilation for the level of CO2 being produced by the body
how is PCO2 measured
- PaCO2 - gold standard
- capnography - best surrogate
- PvCO2 - acceptable surrogate
normal PaCO2 and when should hypoventilation be treated
40 mmHg
treatment should be considered when PaCO2 > 60 mmHg
what does PO2 measure
oxygenation