Anesthesia care for Abdominal Procedures Flashcards

Describe anesthetic considerations, Identify appropriate management plans, Discuss alternative anesthetic techniques, Summarize anesthetic implications and management and Summarize the potential surgical anesthetic risks/complications for abdominal surgery.

1
Q

Name the Intraperitoneal Abdominal Organs

A
SDS JILT
S = Stomach
D = (Bulb of) Duodenum
S = Spleen
J = Jejunum
I = Ileum
L = Liver 
T = Transverse colon, and sigmoid colon
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2
Q

Name the Retroperitoneal Abdominal Organs

A
SAD PUCKER
S = Suprarenal (adrenal) glands.
A = Aorta/Inferior Vena Cava.
D = Duodenum (second and third segments)
P = Pancreas.
U = Ureters.
C = Colon (ascending and descending only)
K = Kidneys.
E = Esophagus.
R = Rectum (sigmoid)
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3
Q

What are the Functions of the Abdominal Wall?

A

-Form firm flexible wall keep viscera in abdominal cavity
-Protect viscera from injury & maintain integrity of wall
-Maintain anatomical position against gravity
-Assist in respiration, forceful ventilation
-Involved in any action increasing abdominal pressure (cough)
assist with respiration and control the expulsive efforts of urination, defecation, coughing, and parturition. They also work with the back muscles to flex and extend the trunk at the hips, rotate the trunk at the waist, and protect viscera by becoming rigid.

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4
Q

What are the 9 Layers of the Abdominal Wall?

A
  1. Skin
  2. Subcutaneous tissue
  3. Superficial fascia
  4. External oblique muscle
  5. Internal oblique muscle
  6. Transversus abdominis muscle
  7. Transversalis fascia
  8. Preperitoneal adipose & areolar tissue
  9. Peritoneum
    Nerves, blood vessels, and lymphatics are present throughout.
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5
Q

Describe the Superficial Fascia.

A
  • Fatty connective tissue
  • Above umbilicus is a single fascial sheet
  • Below umbilicus are 2 fascial sheets
  • Superficial vessels, lymph nodes & nerves in between
  • Important Features of Superficial Fascia:
  • Superficial fascia is most distinct in the lower part of the anterior abdominal wall, perineum, and the limbs.
  • Superficial fascia shows stratification (into two layers) in the lower part of anterior abdominal wall, perineum, and uppermost parts of thighs.
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6
Q

Describe & Name Flat Muscles of Abdominal Wall.

How many are there?

A

3 Flat Muscles of Abdominal Wall are:
External Oblique
Internal Oblique
Transversus Abdominis

These muscles are located laterally in the abdominal wall, stacked upon one another. Running in different directions & crossing each other strengthening the wall, and decreasing the risk of herniation.
Each flat muscle forms an aponeurosis (a broad, flat tendon) which covers the vertical rectus abdominis muscle. The aponeuroses of all the flat muscles become entwined in the midline, forming the linea alba.

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7
Q

What is the Linea Alba?

A

The white line (Latin: linea alba) is a fibrous structure that runs down the midline of the abdomen in humans and other vertebrates. In humans linea alba runs from the xiphoid process to the pubic symphysis.

It is formed by the fusion of the aponeuroses of the abdominal muscles & it separates the left and right rectus abdominis muscles. In muscular individuals its presence can be seen on the skin, forming the depression between the left and right halves of a “six pack”.

Because it consists of mostly connective tissue, and does not contain any primary nerves or blood vessels, a median incision through the linea alba is a common surgical approach.

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8
Q

Discuss the flat muscle: External Oblique.

A

Originates from Ribs 5-12
Inserts into Iliac Crest and pubic tubercle
Contralateral rotation torso.
Innervation: Thoracoabdominal nerves (T7-T11) and subcostal nerve (T12).

External oblique important functions:

  • major role in maintenance of abdominal tone.
  • It helps in completion of micturition, parturition and defecation & vomiting by compressing the abdominal contents.
  • assists in flexing and rotating the trunk.
  • assists in forced expiration.
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9
Q

Discuss the flat muscle: Internal Oblique:

A

Originates from Inguinal ligament, iliac crest and lumbodorsal fascia,
Inserts into ribs 10-12
Bilateral contraction compresses the abdomen, while unilateral contraction ipsilaterally rotates the torso.
Innervation: Thoracoabdominal nerves (T6-T11), subcostal nerve (T12) and branches of the lumbar plexus.

Internal Oblique important functions:

  • Supports the abdominal wall.
  • Assists in forced respiration.
  • Aids in raising pressure in the abdominal area.
  • Rotates and turns the trunk with help from other muscles.
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10
Q

Discuss the flat muscle: Transversus Abdominis:

A

Originates from Inguinal ligament, costal cartilages 7-12, the iliac crest and thoracolumbar fascia
Inserts into the conjoint tendon, xiphoid process, linea alba and the pubic crest.
Compression of abdominal contents.
Innervation: Thoracoabdominal nerves (T6-T11), subcostal nerve (T12) and branches of the lumbar plexus.

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11
Q

Vertical Muscles–Rectus Abdominis

A

The rectus abdominis is long, paired muscle, found either side of the midline in the abdominal wall. It is split into two by the linea alba.
At several places, the muscle is intersected by fibrous strips, known as tendinous intersections. The tendinous intersections and the linea alba give rise to the ‘six pack’ seen in individuals with a well-developed rectus abdominis.
Attachments: Originates from the crest of the pubis, before inserting into the xiphoid process of the sternum and the costal cartilage of ribs 5-7.
Functions: As well as assisting the flat muscles in compressing the abdominal viscera, the rectus abdominis also stabilizes the pelvis during walking, and depresses the ribs.
Innervation: Thoracoabdominal nerves (T7-T11).

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12
Q

Vertical muscles–Pyramidalis

A

This is a small triangular muscle, found superficially to the rectus abdominis. It is located inferiorly, with its base on the pubis bone, and the apex of the triangle attached to the linea alba.
Attachments: Originates from the pubic crest and pubic symphysis before inserting into the linea alba.
Functions: It acts to tense the linea alba.
Innervation: Subcostal nerve (T12).

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13
Q

What structures/organs are perfused by the inferior mesenteric artery (IMA)?

Perfusion of abdominal structures: IMA

A

The inferior mesenteric artery (IMA) supplies arterial blood to the organs of the hindgut – the distal 1/3 of the transverse colon, splenic flexure, descending colon, sigmoid colon and rectum.

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14
Q

What are 3 major branches from the IMA?

A

left colic artery,
sigmoid artery
superior rectal artery.

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15
Q

What structure does the IMA branch from?

A

The inferior mesenteric artery (IMA) is a major branch of the abdominal aorta.

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16
Q

What structures/organs are perfused by the superior mesenteric artery (SMA)?

A

The SMA supplies the intestine from the lower part of the duodenum through two-thirds of the transverse colon, as well as the pancreas.

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17
Q

What structure does the SMA branch from?

A

The superior mesenteric artery (SMA) arises from the anterior surface of the abdominal aorta, just inferior to the origin of the celiac trunk,

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18
Q

Perfusion abdominal structures: Superior Mesenteric Artery (SMA)

A

Branch: inferior pancreaticoduodenal artery
Supplies: head of the pancreas and to the ascending and inferior parts of the duodenum

Branch: intestinal arteries
Supplies: branches to ileum, branches to jejunum

Branch: ileocolic artery
Supplies: supplies last part of ileum, cecum, and appendix

Branch: right colic artery
Supplies: to ascending colon

Branch: middle colic artery
Supplies: to the transverse colon

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19
Q

What are the two systems responsible for venous drainage of abdominal structures?

A

Two venous systems drain abdominal structures:

Portal system transports venous blood to liver for processing via Portal Vein.

Systemic venous system returns deoxygenated blood to right atrium of the heart via the Inferior Vena Cava (IVC).

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20
Q

What are the Portal Veins (PV) functions?

A
Carries venous blood to liver for processing.
Portal Vein (PV) drains spleen, pancreas, gallbladder, abdominal part of GI tract.
Portal Vein is formed by the union of the splenic vein & the superior mesenteric vein, posterior to the neck of the pancreas, at the level of L2.
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21
Q

What Tributaries does the Portal Vein receive?

A

PV receives additional tributaries from: R&L Gastric, Cystic (Gb), Para-umbilical

Immediately before entering the liver, the portal vein divides into R&L branches which then enter the parenchyma of the liver separately.

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22
Q

What is the Role of the Inferior Vena Cava (IVC)?

A

Systemic venous system returns blood to right atrium of the heart.
Transports de-oxygenated blood to Right Atrium
The Inferior Vena Cava—Posterior Abdominal Wall (anterior Vertebral Column & Right of Aorta) responsible for venous drainage of all structures below the diaphragm. IVC receives tributaries from common iliac, lumbar, renal (drains kidneys-left adrenal-left testes/ovaries), right suprarenal, right testicular/ovarian, inferior phrenic & hepatic veins

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23
Q

Explain Langer’s lines:

A

Ideally an incision should provide easy access to desired structures, be aesthetically pleasing & heal quickly w minimal scarring.
Also known as skin cleavage or tension lines.
Considered to affect scarring and outcome, Langers Lines are suggestions for incisional sites.

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24
Q

What is the Clinical Relevance of the Vertical Abdominal Incision– Median?

A

Median
An incision that is made through the linea alba. It can be extended the whole length of the abdomen, by curving around the umbilicus. The linea alba is poorly vascularized, so blood loss is minimal, and major nerves are avoided. All can be used in any procedure that requires access to the abdominal cavity.

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25
Q

What is the Clinical Relevance of the Vertical Abdominal Incision– Paramedian?

A

Paramedian
Similar to the median incision, but is performed laterally to the linea alba, providing access to more lateral structures (kidney, spleen and adrenals). This method ligates the blood and nerve supply to muscles medial to the incision, resulting in their atrophy.

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26
Q

What is the Clinical Relevance of the Transverse Abdominal Incision– Suprapubic (Pfannenstiel)?

A

Suprapubic (Pfannenstiel)
are made 5cm superior to the pubis symphysis.
used when access to the pelvic organs is needed.
care must be taken not the perforate the bladder as the fascia thins around the bladder area.

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27
Q

What is the Clinical Relevance of the Transverse Abdominal Incision– Subcostal?

A

Subcostal
starts inferior to the xiphoid process, and extends inferior parallel to the costal margin.
mainly used on the right side to operate on the gall bladder and on the left to operate on the spleen.

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28
Q

What is the Clinical Relevance of the Transverse Abdominal Incision– McBurney?

A

McBurney
a ‘grid iron’ incision (consists of two perpendicular lines, splitting the fibres of the muscles without cutting them) – this allows for excellent healing.
performed at McBurney’s point (1/3 of the distance between the ASIS {anterior superior iliac spine and the umbilicus).
mostly used in appendectomies.

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29
Q

What is the Clinical Relevance of the Transverse Abdominal Incision– Transverse?

A

Transverse
made just inferior and laterally to the umbilicus.
commonly used (causes least damage to the nerve supply to the abdominal muscles, and heals well).
The incised rectus abdominis heals producing a new tendinous intersection.
Used in operations on the colon, duodenum and pancreas.

30
Q

What are anesthetic considerations in abdominal surgery?

A
*Procedure Type 
   Open, Laparoscopic, Laparoscopic Robotic
   Surgical Risk Stratification (Very low to Very high)
*Pre-operative Evaluation 
*Patient Risks (ASA/PMH) 
*Nutritional /Fluid Status (ERAS)
*Bowel Prep/Vomiting/Diarrhea
*Blood Loss (estimated/allowable)
31
Q

Describe some Benefits of Open Abdominal Surgical Technique.

A
(Most Cases) Better Visualization
Easy Access 
Reduces Case Duration
Improved Tactile Sensation
Reduces complications caused with laparoscopic/robotic procedures
32
Q

Disadvantages of Open Abdominal Surgical Technique. Include:

A
Larger Incision
More Pain (subjective/in many cases)
Longer Recovery Period
Increased Costs
Higher Risks of Complications (bleeding, infection)
33
Q

What are some Advantages of Laparoscopic Surgical Technique?

A

Minimally Invasive
Less Pain
Reduced Blood Loss

34
Q

What are some Disadvantages of Laparoscopic Surgical Technique?

A
  • Trocar Placement Injury
  • Instrument manipulation injury
  • Pneumoperitoneum
  • Gas Embolism
  • Positioning
  • Subcutaneous Emphysema
35
Q

Describe The Pneumoperitoneum:

A
  • Allows view of structures
  • Room for instrument manipulation
  • Create artificial pneumoperitoneum
  • Initial entry may lead to injury
  • Entry technique (open vs closed)
  • Entrained Gas is carbon dioxide (CO2)
36
Q

The Mechanical Effects of Peritoneal Insufflation Include:

A
  • Impaired ventilation
  • Perfusion of compressed alveoli causes shunt with –Impaired oxygenation and CO2 elimination.
  • Pulmonary compliance has been observed to be reduced by 43%
  • Trendelenburg position has been shown to increase the effects of pneumoperitoneum on pulmonary mechanics.
37
Q

Pulmonary Function Changes Associated With Pneumoperitoneum:

A
  • Positive inspiratory pressure (PIP) ↑
  • Intrathoracic pressure ↑
  • Pulmonary compliance dV/dP ↓
  • Vital capacity ↓
  • Functional residual capacity ↓
38
Q

What are some of the Complications r/t creation of Pneumoperitoneum?

A
  • Injury upon insertion (bowel, bladder, uterus,visceral injuries, vascular (inferior vena cava, aorta, and iliac arteries & veins)
  • Unilateral or bilateral pneumothorax
  • Pneumomediastinum
  • Pneumopericardium
  • Air Embolism
  • Bradycardia
  • Retroperitoneal hematomas (may not see)
39
Q

What causes bradycardia during Laparoscopic Insufflation?

Insufflation after Significant Bradycardia:

A
  • Vagal-mediated cardiovascular reflex.
  • Rapid peritoneum distension w insufflation
  • Gas embolism

Reducing to Low Flow & Limiting intra-abdominal pressure (IAP) below 12-15 mmHg during insufflation is known to be effective to prevent pathophysiological changes of pneumoperitoneum (low flow & low pressure).

40
Q

Treatment for bradycardia during Laparoscopic (+/-) Robotic Surgical Procedures:

A
  • Stop Insufflation (Deflate pneumoperitoneum by removing trocar)
  • Treat bradycardia with Atropine as needed
41
Q

Anesthetic Management for Laparoscopic Surgery

A

Local, regional, and general anesthetic techniques.
Local anesthesia with sedation, low pressure, 1 port quick diagnostic case.
GA most common.
Regional: Need high (T4) sensory levels patient may feel discomfort 2* high block.
LMA controversial (no general consensus exists to date).

42
Q

Postoperative Concerns for Laparoscopic Surgery

A

PONV as high as 72% incidence
surgical wound dehiscence, aspiration, and unanticipated hospital admission.
total intravenous anesthesia (TIVA) & anti-emetics reduce PONV <10%.
Pain

43
Q

What are the 3 Components of Pain with Laparoscopic Surgery?

A

Pain r/t 3 components
1. incisional pain (parietal pain).
2. deep intra-abdominal pain (visceral pain).
3. shoulder pain, which is believed to be referred visceral pain.
Also: CO2 insufflation irritates phrenic nerve.

44
Q

Describe Laparoscopy & Gas embolism:

What is the Incidence of SIGNIFICANT Gas Embolism? Mortality?

A

A direct entrainment of air and/or other medical gases, such as carbon dioxide, into the arterial or venous system.
Significant gas embolism is rare, having a reported incidence of 0.001% to 0.59% and an associated mortality rate of up to 28.5%.

45
Q

Laparoscopy & Gas embolism:

A

Massive and/or fatal gas embolisms have been reported during all types of laparoscopic procedures including laparoscopic cholecystectomy, liver resection, and hysterectomy.
It can occur any time there are open vessels that have an intravascular pressure that is below intra-abdominal pressure or with the erroneous placement of a Veress needle or trocar directly into the lumen of an intra-abdominal vessel.
Studies that have evaluated methods of increasing CVP, such as the use of PEEP, in order to decrease the pressure gradient across vessels have not shown them to be effective in reducing the incidence of gas embolism.

46
Q

Describe Minor Gas Embolisms:

Incidence?

Symptoms of Large Volumes of Intravascular gas?

A

Studies & TEE monitoring of pulmonary artery pressure have shown that the actual incidence of gas embolism during laparoscopic procedures is between 65% and 100%.
The majority of these embolisms, although minor, were still associated with respiratory and hemodynamic changes that usually resolved spontaneously.
Intravascular insufflation of large volumes of gas can travel to the right side of the heart where they enter the pulmonary circulation and lodge in the pulmonary outflow tract, causing increased pulmonary artery pressure, right ventricular failure, decreased pulmonary venous return with subsequent decreased left ventricular preload, decreased cardiac output, asystole, and cardiovascular collapse.

47
Q

Describe Helium Insufflation for Abdominal Laparoscopic (+/-) Robotic Procedures:

A

Other gases such as helium have been utilized for peritoneal insufflation in order to avoid the negative side effects of CO2 insufflation including CO2 accumulation, hypercarbia, acidosis, and sympathetic nervous system stimulation, particularly in patients with preexisting impairment in respiratory function (COPD, infancy). Although helium pneumoperitoneum is associated with a greater degree of cardiopulmonary stability, there appears to be a higher incidence of subcutaneous emphysema and life-threatening gas embolism even with entrainment of small volumes.

48
Q

What are the S&S of Significant Gas Embolism in the Anesthetized Patient?

A
  • An acute Decrease or loss of end-tidal partial pressure of carbon dioxide (PETCO2), an Increase in end-tidal nitrogen,
  • which is accompanied by Hypotension and/or
  • Hypoxia (cannot be explained by deep anesthesia or hypovolemia).
  • Dysrhythmias,
  • Severe Hemodynamic instability, and
  • Cardiovascular collapse can occur when large volumes of gas are entrained, especially in patients with impaired cardiovascular function and minimal cardiac reserve.
49
Q

How is a Gas Embolism Diagnosed?

A

Diagnosis of gas embolism depends upon recognition of the physiologic manifestations of gas emboli and/or visual detection of gas emboli in the right side of the heart and pulmonary outflow tract.
Transesophageal echocardiography is the most sensitive diagnostic technique for the detection of gas emboli & can identify emboli as small as 0.02 mL/kg.
TEE technology is rarely used because these volumes of air are well tolerated and usually not associated with hemodynamic changes. Changes in Doppler sounds and increases in pulmonary artery pressures will occur with volumes of 0.5 mL/kg of gas. Unfortunately, when the “classic mill wheel murmur” is audible, gas volumes of 2 mL/kg or more have been entrained, and significant hemodynamic instability is present manifesting in tachycardia, hypotension, cardiac dysrhythmias, cyanosis, and electrocardiogram (ECG) changes indicative of right-sided heart strain.

50
Q

Management of Gas Embolis:

A

Management:
-Halting the insufflation of gas
eliminating nitrous oxide (N2O) (prevent expansion)
-Releasing the pneumoperitoneum
-Flooding the field with normal saline (halt gas entrainment)
-Placing the patient in left lateral decubitus position (Durant maneuver)
-Aspirating the gas through a central venous catheter if in place,
-Supporting the hemodynamics with volume & pressors as required
{Low CVP increases the risk of venous gas embolism; therefore adequate hydration should be provided for the patient undergoing laparoscopy. However, the decision to obtain central venous access during laparoscopic procedures is guided by the complexity of the surgical procedure and presenting comorbidities of the patient, rather than as a means of managing perioperative gas embolism.}

51
Q

Management of Subcutaneous Emphysema

A

• Decrease intra-abdominal pressure, if possible terminate pneumoperitoneum
• Discontinue nitrous oxide because it can increase subcutaneous emphysema volume
• Place on 100% FiO2
• Evaluate for a pneumothorax
• Increase minute ventilation to treat hypercarbia
• Evaluate ETCO2 and PaCO2
• Assess chest wall and lung compliance
• Assess airway to rule out compression prior to extubation
ETCO2, End-tidal CO2; FiO2, fraction of inspired oxygen; PaCO2, partial pressure of arterial CO2.

52
Q

What is the Multimodal Pain Management Approach after Laparoscopic Surgery?

A

Multimodal approach opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and local anesthetics.
The multimodal approach has been found to improve patient satisfaction, decrease opioid requirements, and decrease the incidence of postoperative complications including PONV and unplanned hospital admission.

53
Q

Describe NSAIDs use in Multimodal Pain Management:

A

NSAIDs have proven to be of value in managing postoperative laparoscopic pain. Several types of NSAIDs have been used including the cyclooxygenase-2 (COX-2) inhibitor celecoxib, ketorolac, and acetaminophen, and their efficacy has been repeatedly studied. NSAIDS synergistically lead to decreased opioid use.

54
Q

Describe Glucocorticoids use in Multimodal Pain Management:

A

Glucocorticoids also have been used successfully for the management of post-laparoscopy pain. In addition to possessing antiemetic properties, glucocorticoids have anti-inflammatory and analgesic properties good for visceral pain.

55
Q

Describe Local Anesthetics use in Multimodal Pain Management:

A
  • The effectiveness of peripherally administered local anesthetics in the management of postoperative laparoscopy pain remains mixed.
  • Infiltration of surgical incisions at the end of procedures was effective in the management of postoperative pain.
  • Intravenous lidocaine infusions were shown to be useful for rescue therapy.
  • Studies of intraperitoneal local anesthesia injection showed that the technique improved overall pain scores but questioned the clinical significance of the treatment effect.
  • Ultrasound-guided transversus abdominus plane (TAP) sheath block, are also proving to be effective in the management of post-laparoscopy pain by blocking the terminal branches of the lower intercostal nerves in a T8 to L1 dermatomal distribution.
56
Q

Describe NMDA Antagonists use in Multimodal Pain Management:

Discussed in Class
Reference: Wick, Grant & Wu

A
N-Methyl-D-Aspartate Antagonists
The N-methyl-D-aspartate (NMDA) class of glutamate receptor are involved with nociceptive processing &amp; 
development of chronic pain. The inhibition of NMDA receptors during the perioperative period is desirable because these agents provide a nonopioid mechanism
of analgesia. Clinically availableNMDA antagonists include ketamine hydrochloride, magnesium sulfate, dextromethorphan hydrobromide (found in cough syrup), and methadone. Ketamine traditionally has been used intraoperatively by anesthesiologists as an anesthetic; however,it can be given postoperatively in subanesthetic doses as an infusion and has been shown to decrease IV PCA morphine use, PONV. Magnesium also can be administered in the perioperative period as an infusion,and pooled data from studies indicate that perioperative magnesium infusion is associated with a decrease in postoperative pain and opioid consumption without clinical toxic effects caused by toxic serum levels of magnesium. A recent meta-analysis indicated that the perioperative use of dextromethorphan was associated with a reduction of postoperative opioid consumption at 24 to 48 hours and pain scores at 1, 4 to 6, and 24 hours. Methadone should not be routinely used postoperatively and typically should be used only in consultation with a pain specialist.
57
Q

Describe Multimodal Pain Management Analgesic Principles:

(Discussed in Class)
Reference: Wick EC, Grant MC, Wu CL. Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and TechniquesA Review. JAMA Surg. 2017;152(7):691–697. doi:10.1001/jamasurg.2017.0898

A

A standardized, regimen is an essential and central component of all ERAS pathways but is also important in the context of the current opioid epidemic. Multimodal analgesia is based on the premise that the concurrent use of primarily nonopioid analgesics
can have additive, if not synergistic, effects that produce superior analgesia while decreasing opioid use and opioid-related side effects. Minimization of opioid use and side effects is a key component of almost any standardized analgesic ERAS pathway, with the multimodal regimen consisting mostly of nonopioid analgesics and techniques

58
Q

Describe Acetaminophen use in Multimodal Pain Management:

Discussed in Class
Reference: Wick, Grant & Wu

A

Like NSAIDs, acetaminophen (given either IV or PO) should be administered on a scheduled rather than on an as needed basis.When added to opioids, acetaminophen produces superior analgesia and an opioid-sparing effect associated with a decrease in some opioid-related adverse events, such as PONV and sedation. Acetaminophen should be concurrently administered with NSAIDs on a scheduled basis (assuming no contraindications) because the administration of both agents will result in an additive, if not synergistic analgesic, effect. The maximum dosage of acetaminophen for a normal-sized adult is commonly quoted at 4 g/d, although the manufacturer of Tylenol in the United States has dropped the maximum daily dose to 3 g/d (see https://www.tylenol.com/safety-dosing /usage/dosage-foradults).
Acetaminophen is hepatically cleared and thus should be
avoided for patients with liver insufficiency

59
Q

Describe Gabapentin use in Multimodal Pain Management:

Discussed in Class
Reference: Wick, Grant & Wu

A

Gabapentanoids (gabapentin and pregabalin) were originally designed as anticonvulsants but have been used for the treatment of chronic neuropathic pain. Meta-analyses indicate that a single dose of gabapentin or pregabalin administered preoperatively is associated
with a decrease in postoperative pain and opioid consumption at 24 hours but an increase in postoperative sedation, dizziness,and visual
disturbances. Gabapentin and pregabalin are
commonly administered during the postoperative period for many ERAS pathways, although the optimal dosing regimen and duration of administration is unclear. Gabapentanoids are renally excreted; thus, the dose should be decreased in patients with renal dysfunction.

60
Q

Summarize Local anesthesia with sedation for Laparoscopic Procedures

A
  • Has been done successfully but rare
  • Challenge of patient needs/understanding
  • Require Cooperative patient
  • Not for large open abdominal procedures
  • Short duration/low flow single port laparoscopy
  • Shorter hospital stay w reduced hospital & anesthesia costs
  • Faster recovery, decreased PONV, fewer hemodynamic changes
61
Q

Summarize General Anesthesia Technique for Laparoscopic Procedures

A

Most common for abdominal procedures
+/- paralysis depending on intra abdominal status
May combine w regional for post-op pain management
Secured airway ETT (LMA has been used-mixed reviews)
Multi-modal Pain Management

62
Q

Summarize Regional Anesthesia Technique for Laparoscopic Procedures

A

Require high block (T-4) for Upper abdominal (T-9) Lower abdominal
Patient may not tolerate high block required (feel short of breath) or feel discomfort from insufflation
May use combined spinal epidural block
Reduced stress response
Early ambulation
Lower incidence of DVT
Used in conjunction with GA for post-op pain management

63
Q

History of Robotic Surgery

A

1980’s NASA developed technology for 3-D space taking concept of virtual reality to engineers for human interface technology to develop extremely dexterous telemanipulator for anastomosis (nerve & vascular) providing surgeons the sense that the surgical field was directly in front of them even when at a distance.
The Laparoscopic Cholecystectomy began in France and quickly became widespread (challenges—no sense of touch, not 3-D, impaired dexterity 2* fulcrum effect {no articulation}).
Earliest robot 1992 FDA approval took time. Military use for remote surgical technologies in battlefield
1997 1st robotic surgery performed, the FDA approved the da Vinci System in 2000.
In 2014 alone, an estimated 570,000 robotic procedures were performed worldwide, the majority of which were hysterectomies and prostatectomies.

64
Q

What are some Considerations during Robotic Surgery?

A

Improved patient outcomes, including decreased length of stay, faster recovery, reduced perioperative blood loss, and reduced postoperative pain.
Fixed robotic arms and attached surgical instruments to the patient –potential for constant compression, (face & chest). Add padding between robotic arms/instruments and patient.
Extreme surgical positions during robotic procedures require vigilance if patients shift/move from gravity. Secure Patients on the operating room table to prevent inadvertent movement & creation of pressure points. Essential that position be assessed at regular intervals (at least every 15 minutes) throughout the procedure or when changes in the position of the patient, robot, or operating room table occur.
(1) prolonged surgical times (w new robotic surgeon)
(2) spatial restrictions associated with use of the robot
(3) inability to alter patient position after docking of the robot
physiologic changes associated with extreme positioning
(4) risk of postoperative visual loss (POVL)
(5) physiologic consequences associated with the creation of pneumoperitoneum (see Chapter 34); and
(6) implementation of Enhanced Recovery after Surgery (ERAS) protocols.

65
Q

What are some Cardiovascular Changes associated with Steep Trendelenburg Positioning?

A
Cardiovascular Changes
•Increased:
•Mean arterial Pressure (MAP)
•Central Venous Pressure (CVP)
•Pulmonary Capillary Wedge Pressure (PCWP)
•Systemic Vascular Resistance (SVR)
•Unchanged:
•Heart rate (HR)
•Stroke Volume (SV)
•Mixed Venous Oxygen Saturation
66
Q

What are some Respiratory Changes associated with Steep Trendelenburg Positioning?

A
Respiratory Changes
•Increased:
•Airway Resistance
•Peak pressure
•Plateau pressure
•End-tidal carbon dioxide (ETCO2)
•Upper airway edema
•Decreased:
•Lung compliance
•Vital capacity (VC)
•Forced Expiratory Volume in 1 second (FEV1)
67
Q

What are some Cerebrovascular Changes associated with Steep Trendelenburg Positioning?

A
Cerebrovascular Changes:
•Increased:
•Intracranial pressure
•Hydrostatic pressure gradient
•Cerebral vascular resistance
•Decreased:
•Cerebral venous drainage
•Unchanged:
•Regional cerebral oxygenation
•Cerebral perfusion pressure
68
Q

Describe Postoperative Visual Loss (POVL) surrounding Robotic and Steep Trendelenburg Positioning.

A

Rare but devastating complication following surgery. It’s been documented after cardiac, spine, head and neck procedures, and, most recently, robotic surgical procedures performed in steep Trendelenburg.
The major causes of POVL include anterior ischemic optic neuropathy (AION), posterior ischemic optic neuropathy (PION), central retinal artery occlusion (CRAO), and cortical blindness.
A large multicenter case-control study conducted by the Postoperative Visual Loss Study Group in 2012 concluded that male gender, obesity, prolonged anesthetic duration, greater estimated blood loss, and a lower percentage of colloid in non-blood replacement were independent risk factors for the development of POVL. Because prolonged surgical time in positions associated with venous congestion and rising intraocular pressures are common in robotic surgery, it has been postulated that similar risk factors would be seen in this surgical population. Although the reported incidence of POVL in robotic surgery is currently low, it is recommended that efforts to reduce the degree of venous congestion and interstitial edema in the head during robotic procedures should be implemented.

69
Q

Describe POVL as Related to Visual System Types of Injuries:

AION

PION

CRAO

A

AION is caused by occlusion or hypo-perfusion of the anterior optic nerve and is most common following cardiac, major vascular, and spine procedures.
PION results from infarction of the optic nerve posterior to the lamina cribrosa, usually as a result of elevated venous pressures, increased intraocular pressures, and interstitial edema, which compromise blood flow to the eye, as seen in prone and steep Trendelenburg positions.
AION and PION present with sudden onset of painless visual loss and visual field deficits, and are usually discovered upon emergence from anesthesia.
CRAO and cortical blindness are usually associated with procedures in which there is a high likelihood of high embolic load, severe hypotension, or direct global compression.

70
Q

Describe Strategies for Prevention of POVL.

A

Minimizing surgical time
Minimizing estimated blood loss
Decreasing venous congestion
The American Society of Anesthesiologists (ASA) and the Anesthesia Patient Safety Foundation (APSF) recommend consideration of
staged surgical procedures to reduce operative time,
keeping the head at or above the level of the heart when possible,
and including colloid in nonblood replacement strategies.
In addition, they highly encourage the anesthesia care provider to include a discussion of risk factors associated with POVL and the current understanding of interventions available to reduce the risk as part of the informed consent process in high-risk patients.

71
Q

What is Enhanced Recovery After Surgery (ERAS)

A

Goal of ERAS: improve surgical outcomes and allow patients to return to normal activity as quickly as possible.
Management pathways have been developed to facilitate this process. The ERAS program is an international, multimodal approach to perioperative care that aims to achieve early recovery following major surgery. It was first designed for application in patients undergoing gastrointestinal procedures, but has been applied across surgical specialties including gynecology, general surgery, orthopedics, and nephrology.

72
Q

Review ERAS protocol use for Abdominal Surgeries.

A

The ERAS protocol is a multidisciplinary, evidence-based list of recommendations for the care of patients during the preoperative, intraoperative, and postoperative periods in an attempt to modify the stress response to surgery so as to improve surgical outcomes. The protocol is comprised of approximately 20 elements that have been shown to decrease hospitalization and perioperative complications
Preoperative guidelines focus on prevention of the catabolic state associated with long periods of fasting and fluid restriction.
Intraoperative and postoperative recommendations are designed to fast-track patients in order to promote early ambulation and feeding following surgery.
ERAS studies have demonstrated a significant decrease in stress response, length of stay, a reduction in major perioperative complications, and similar rates of readmission in patients receiving ERAS-based versus conventional care.