anesthesia Flashcards
- general anesthesia via vaporizer and carrier gas
- when inhaled partial pressure of gas = blood and goes through body
- dose is percent end-tidal agent and MAC is end-tidal level of gas needed to prevent movment to noxious stimulate in 50% of patients
inhaled anesthesia
3 cardiac effects of inhaled agents
decreases 3 things: contractility, SVR and MAP
- ischemia in pt with fixed stenotic lesions
- valvular heart disease
- cardiomyopathy
- congenital defects
these are implications of cardiac effects of what type of anesthesia?
inhaled agents
what MET level are you concerned about with a patient going into surgery?
less than 4 METs
3 signs of CHF
JVD
L.E edema
crackles
4 pulm effects of inhaled agents
- bronchodilation
- decreased respiratory drive
- increased respiratory rate with decreased tidal volume
- atelectasis
- increased CO2 threshold to breathe– issue for OSA
decreased breath sounds suggests what 4 conditions might be at play?
atelectasis
infection– could also have crackles or rhonchi
COPD
pneumothorax
2 CNS effects of inhaled agents
- increased cerebral blood flow & ICP
- decreased cerebral metabolic demand
4 neuro labs/imaging to get
CT/MRI for mass effect
plasma levels of anticonvulsant meds
carotid US for detection of carotid dz
MRI for ischemic changes
fam h.o prolonged medication reactions is indicative of …
pseudocholinesterase deficiency
fam h.o high fevers, unexplained cardiac arrest is indicative of …
malignant hyperthermia
what is this condition? what 3 things can happen as it progresses?
- autosomal dom defect in ryanodine receptor that releases calclium
- hypersensitive to releasing stimuli & hyposensitive to inactivating signals
malignant hyperthermia
- acidosis, hyperK, arrhythmia
2 triggering agents of MH
- volatile anesthetic gasses– sevo-, iso-, des-flurane
- succinylcholine (nondepolarizing muscle relaxant)
2 things you see with MH
- increased: RR, CO2, HR, temp
- myoglobinuria
how is MH tx
- stop agent, give DANTROLENE 2.5mg/kg
- support: decrease temp, manage hyperK