Anesthesia Flashcards
1
Q
What is noteworthy about etomidate?
A
Anesthetic with the least hemodynamic effect
2
Q
What is noteworthy about ketamine
A
Anesthetic with the least respiratory effect
3
Q
What are the three components of the general structure of local anesthetics
A
Lipophilic group, intermediate chain, ionizable group
4
Q
What are the derived attributes of the three components of the LA structure?
A
Lipophilic group: CNS distribution and duration
Intermediate chain: implications for PK and toxicity
Ionizable group: Interaction with sodium channels.
5
Q
What is the difference between ester and amide LA?
A
Ester formulations are associated with higher incidence of allergic reactions
