Anemia_PHARM

Question 1

Iron dose and duration
Iron deficiency anemia

Answer 1

60-200mcg elemental iron/day
3-6 months

325mg iron tablet (65mg elemental iron)

Question 2

Vitamin C dosage
Prescribed with Iron

Answer 2

250-500mg vitamin C

Question 3

Vitamin B12 dose and duration
Vitamin B12 anemia

Answer 3

500-1000mcg/day Vitamin B12 (cyanocobalamin)
PO and IM

Question 4

When to choose IM vs. PO
Vitamin B12 anemia

Answer 4

IM
- Neurologic complications
- 1000mcg IM daily for 1-2 weeks
- 1000mcg PO daily

Question 5

laboratory diagnostics for pernicious anemia

Answer 5

• Serum Vitamin B12
• Serum folate (usually co-occur)
• MMA (methylmalanic acid) high in Vitamin B12 anemia
• Homocysteine (high in folate anemia)
• anti-intrinsic factor auto-antibody
• anti-parietal cell auto-antibodies
• H. pylori breath test

Question 6

Folate dosage, duration
Folic acid anemia

Answer 6

Folate

Prophylaxis, preganncy
400-600mcg/day

Deficiency
5000mcg/day for 4 months

Malabsorption
15000mcg/day

Question 7

Laboratory F/U anemia

Answer 7

2 weeks
- normal MMA and homocysteine (vitamin B12, folate)
- response MCV and hemoglobin (increase 20g/L)

8 weeks
- normal hemoglobin
- normal MCV

6 months
- neurological response Vitamin B12