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Pharm Test 2 > Anemia Info > Flashcards

Anemia Info Flashcards

0
Q

Side effects of Fe therapy

A

Painful injections
Oral causes GI upset
Fe deficiency causes Hypochromic, microcytic anemia

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1
Q

Anemia therapies

A

Iron
B9: Folic acid
B12
Epogen (Epoetin)

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2
Q

B9: Folic acid deficiency causes

A

Pregnancy, lactation, intestinal pathology preventing reabsorption (Crohns disease), alcoholism
Folate required for DNA synthesis
Causes mega lactic anemia

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3
Q

B12 deficiency

A

Pernicious anemia

Also causes megiblastic anemia, so often given with B9

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4
Q

Darbepotin (Aranesp) side effects

A

High risk for abuse!!

Stroke, tumor, thrombosis, HTN, death

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5
Q

Hydroxyurea MOA

A

Causes sicke cell hemoglobin to be diluted out due to production of fetal hemoglobin, particularly with epo alpha

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6
Q

Pentoxyfilline

A

Rheologic modifier: increased flexibility of RBC so don’t get stuck in capillaries
Future possibility of stroke, TIA, diabetic ulcers, etc

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Pharm Test 2 (19 decks)

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