Anemia Flashcards
First step in microcytic anemia?
Trial of iron supplement to rule in/out IDA
What would indicate beta thalassemia trait on hemoglobin electrophoresis?
Elevated A2 hemoglobin
If two people with beta thalassemia trait have a kid, what are the chances that the baby will have beta thalassemia?
1 in 4
Hemoglobin cutoff for anemia in pregnancy?
<10.5
What medication do you not want to give to a patient with G6PD deficiency?
Nitrofurantoin, sulfonamides, antimalarial agents
Most common cause of anemia in pregnancy
IDA
Severe anemia in pregnancy
<7
Risk factors for hemoglobinpathies
AA, SE Asian, Mediterranean
Ferritin level in IDA
Low (storage)
Therapy for beta thalassemia minor in pregnancy
Folic acid supplement
Sickle cell anemia mutation
Point mutation in beta globin chain - glutamic acid to valine
1 cause of macrocytic anemia in pregnancy
Folate deficiency (because B12 stores are large)
Anemia, jaundice, thrombocytopenia in pregnant woman
Consider HELLP syndrome
Treatment for HELLP syndrome
Delivery
Elevated hemoglobin F
alpha thalassemia