Anemia Flashcards
microcytic anemia includes (general)
anemia of chronic disease iron deficiency sideroblastic anemia thalassemia lead poisoning
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Fe deficiency
Thalassemia
Lead poisoning
Normocytic anemia (general)
chronic disease
renal disease
infections
acute blood loss
Macrocytic (general)
B12 and folic acid deficiency
abnormal DNA synthesis
bleeding and blood loss –>
normocytic
renal problems (kidneys) –>
normocytic
Iron problems –>
microcytic
thalassemia –>
microcytic
B12 deficiency –>
macrocytic
abnormal DNA synthesis –>
macrocytic
if Fe levels are low –>
Fe deficiency anemia (microcytic)
is serum ferritin is normal or elevated –>
thalassemia or sideroblastic
if serum ferritin is normal, and total iron binding capacity it normal —>
lead poisoning (microcytic anemia)
causes of macrocytic anemia
deficiency of B12 def. of folic acid drugs affecting deoxyribonucleic acid (DNA synthesis) inherited disorders of DNA synthesis liver disease hypothyroidism and hypopituitarism accelerated erythropoiesis (recitculocyte levels) hypoblastic/aplastic anemia infiltrated bone marrow acute leukemia
All about normocytic anemia
1) anemia of chronic DX
2) has an endocrine etiology
3) acute blood loss
4) renal failure
5) hypersplenism
6) neonatal anemia
7) hemolysis
with an iron deficiency, you would expect your ferritin, iron, TIBC and transferrin levels to be
Fe - low
ferritin - low
TIBC -high
transferrin - high