Andrology/Infertility Flashcards
Which surgical operation is advised for the treatment of a 50-year-old man with Peyronie’s disease, short penis, a 75° dorsal curvature an IIER-5 score of 24 (out of 25)?
A. Nesbit’s corporoplasty
B. Penile prosthesis implantation
C. Plaque excision/incision and grafting
D. Nesbit’s corporoplasty + 1 or more plications
C. Plaque excision/incision and grafting
A semen analysis from a 34-year-old man shows a volume 4mL, pH 7.3, sperm count 40,000,000/mL, round cell count 5%, fructose 280 mg/L. Physical examination shows a left grade 2 varicocele. What is the most likely conclusion from these data?
A. Oligoasthenospermia
B. This semen analysis is normal
C. Bilateral obstruction of the vasa deferentia
D. Chronic infection of prostate and seminal vesicles
B. This semen analysis is normal
Chronic oral vardenafil therapy provided to diabetic animals over a 6-weeks treatment period demonstrated:
A. Increased expression of eNOS
B. Increased fibrosis within the penile biopsies
C. Tachyphylaxis with reduced efficacy over time
D. Protein alterations in a dose-dependent fashion
A. Increased expression of eNOS
Androgen deficiency is more common in:
A. Obese men
B. Men with LUTS
C. Men from higher social class
D. Patients with prostate cancer
A. Obese men
The most frequent complication of intra-cavernous injection of prostagladin E1 in patients with erectile dysfunction is:
A. Pain
B. Haematoma
C. Penile fibrosis
D. Prolonged erection
A. Pain
A 30-year-old man with a history of chronic sinusitis, bronchihectasis and situs inversus, presents with a semen analysis showing a normal sperm count but markedly reduced sperm motility. Which is the most likely diagnosis?
A. Noonan syndrome
B. Kallman syndrome
C. Kartagener syndrome
D. Klinefelter syndrome
C. Kartagener syndrome
Which PDE5 inhibitor has the highest affinity for PDE5?
A. Tadalafil
B. Vardenafil
C. Sildenafil
D. Apomorphine
B. Vardenafil
What should be done in patients with erectile dysfunction who do not respond to PDE5 inhibitors?
A. Additional counselling regarding drug dose and usage
B. Switching to second-line therapy
C. Offering vacuum devices
D. Prescribing combination therapy
A. Additional counselling regarding drug dose and usage
The right definition of infertility is the inability of sexually active couples who are not using contraception to achieve spontaneous pregnancy within:
A. 6 months
B. One year
C. 18 months
D. Two years
B. One year
Congenital bilateral absence of the vas deferens is associated with:
A. Von Hippel-Lindau Syndrome
B. Bourneville syndrome
C. Cystic fibrosis
D. Birt-Hogg-Dubé syndrome
C. Cystic fibrosis
Which of the following neurotransmitters is involved in penile detumescence?
A. Acetylcholine
B. Vasoactive intestinal polypeptide
C. Norepinephrine
D. Dopamine
C. Norepinephrine
Congenital penile curvature is most frequently:
A. Lateral
B. Ventral
C. Dorsal
D. Both lateral and dorsal
B. Ventral
Subclinical varicocele is:
A. Not palpable or visible at rest or during Valsava manoeuvre, but visible on Doppler ultrasound
B. Not palpable or visible at rest but during Valsava manoeuvre
C. Palpable at rest, but not visible
D. Palpable and visible but without clinical manifestation
A. Not palpable or visible at rest or during Valsava manoeuvre, but visible on Doppler ultrasound
Which is correct about Peyronie disease?
A. It does not commonly coincide with ED
B. It should be operated in the active phase as early as possible
C. The treatment with grafts should not be used if >60 degree deviation or hourglass deformity
D. Plication is a good treatment alternative in patients with <60 degree deviation
D. Plication is a good treatment alternative in patients with <60 degree deviation
A cause of primary hypogonadism is:
A. Pituitary adenoma
B. Hyperprolactinemia
C. Kallmann syndrome
D. Klinefelter syndrome 47, XXY
D. Klinefelter syndrome 47, XXY