Andrology/Infertility Flashcards

1
Q

Which surgical operation is advised for the treatment of a 50-year-old man with Peyronie’s disease, short penis, a 75° dorsal curvature an IIER-5 score of 24 (out of 25)?

A. Nesbit’s corporoplasty
B. Penile prosthesis implantation
C. Plaque excision/incision and grafting
D. Nesbit’s corporoplasty + 1 or more plications

A

C. Plaque excision/incision and grafting

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2
Q

A semen analysis from a 34-year-old man shows a volume 4mL, pH 7.3, sperm count 40,000,000/mL, round cell count 5%, fructose 280 mg/L. Physical examination shows a left grade 2 varicocele. What is the most likely conclusion from these data?

A. Oligoasthenospermia
B. This semen analysis is normal
C. Bilateral obstruction of the vasa deferentia
D. Chronic infection of prostate and seminal vesicles

A

B. This semen analysis is normal

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3
Q

Chronic oral vardenafil therapy provided to diabetic animals over a 6-weeks treatment period demonstrated:

A. Increased expression of eNOS
B. Increased fibrosis within the penile biopsies
C. Tachyphylaxis with reduced efficacy over time
D. Protein alterations in a dose-dependent fashion

A

A. Increased expression of eNOS

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4
Q

Androgen deficiency is more common in:

A. Obese men
B. Men with LUTS
C. Men from higher social class
D. Patients with prostate cancer

A

A. Obese men

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5
Q

The most frequent complication of intra-cavernous injection of prostagladin E1 in patients with erectile dysfunction is:

A. Pain
B. Haematoma
C. Penile fibrosis
D. Prolonged erection

A

A. Pain

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6
Q

A 30-year-old man with a history of chronic sinusitis, bronchihectasis and situs inversus, presents with a semen analysis showing a normal sperm count but markedly reduced sperm motility. Which is the most likely diagnosis?

A. Noonan syndrome
B. Kallman syndrome
C. Kartagener syndrome
D. Klinefelter syndrome

A

C. Kartagener syndrome

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7
Q

Which PDE5 inhibitor has the highest affinity for PDE5?

A. Tadalafil
B. Vardenafil
C. Sildenafil
D. Apomorphine

A

B. Vardenafil

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8
Q

What should be done in patients with erectile dysfunction who do not respond to PDE5 inhibitors?

A. Additional counselling regarding drug dose and usage
B. Switching to second-line therapy
C. Offering vacuum devices
D. Prescribing combination therapy

A

A. Additional counselling regarding drug dose and usage

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9
Q

The right definition of infertility is the inability of sexually active couples who are not using contraception to achieve spontaneous pregnancy within:

A. 6 months
B. One year
C. 18 months
D. Two years

A

B. One year

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10
Q

Congenital bilateral absence of the vas deferens is associated with:

A. Von Hippel-Lindau Syndrome
B. Bourneville syndrome
C. Cystic fibrosis
D. Birt-Hogg-Dubé syndrome

A

C. Cystic fibrosis

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11
Q

Which of the following neurotransmitters is involved in penile detumescence?

A. Acetylcholine
B. Vasoactive intestinal polypeptide
C. Norepinephrine
D. Dopamine

A

C. Norepinephrine

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12
Q

Congenital penile curvature is most frequently:

A. Lateral
B. Ventral
C. Dorsal
D. Both lateral and dorsal

A

B. Ventral

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13
Q

Subclinical varicocele is:

A. Not palpable or visible at rest or during Valsava manoeuvre, but visible on Doppler ultrasound
B. Not palpable or visible at rest but during Valsava manoeuvre
C. Palpable at rest, but not visible
D. Palpable and visible but without clinical manifestation

A

A. Not palpable or visible at rest or during Valsava manoeuvre, but visible on Doppler ultrasound

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14
Q

Which is correct about Peyronie disease?

A. It does not commonly coincide with ED
B. It should be operated in the active phase as early as possible
C. The treatment with grafts should not be used if >60 degree deviation or hourglass deformity
D. Plication is a good treatment alternative in patients with <60 degree deviation

A

D. Plication is a good treatment alternative in patients with <60 degree deviation

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15
Q

A cause of primary hypogonadism is:

A. Pituitary adenoma
B. Hyperprolactinemia
C. Kallmann syndrome
D. Klinefelter syndrome 47, XXY

A

D. Klinefelter syndrome 47, XXY

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16
Q

For the diagnosis of male hypogonadism, testosterone is recommended to be measured in the:

A. Morning before 11.00 hours, preferably in the fasting state
B. Morning before 11.00 hours, preferably after breakfast
C. Afternoon after 15.00 hours, preferably in the fasting state
D. Afternoon after 15.00 hours, preferably after lunch

A

A. Morning before 11.00 hours, preferably in the fasting state

17
Q

In which anatomical site is most often the cause for obstructive azoospermia?

A. Ejaculatory duct
B. Vas deferens
C. Epididymis
D. Inside testis

A

C. Epididymis

18
Q

Which medication used for the treatment of erectile dysfunction has the highest Tmax (time-to-maximum plasma concentration value)?

A. Sildenafil
B. Tadalafil
C. Vardenafil
D. Avanafil

A

B. Tadalafil

19
Q

High-flow priapism:

A. Is an emergency and must be treated immediately
B. Does not disturb sexual intercourse
C. Is commonly caused by blunt perineal trauma
D. Is usually the cause of an intermittent priapism

A

C. Is commonly caused by blunt perineal trauma

20
Q

Testosterone levels follow a circadian rhythm, when is the highest peak?

A. Morning
B. Afternoon
C. Evening
D. Night

A

A. Morning

21
Q

Priapism is defined as a persistent penile erection that continues for more than:

A. 2 hours
B. 4 hours
C. 6 hours
D. 10 hours

A

B. 4 hours

22
Q

What is the recurrence rate after high ligation for a varicocele?

A. 0-5%
B. 5-10%
C. 10-20%
D. 20-40%

A

D. 20-40%

23
Q

According to the EAU guidelines spontaneous resolution in Peyronie disease occurs in about:

A. 10%
B. 20%
C. 30%
D. 40%

A

A. 10%

24
Q

A 35-year-old man complains of premature ejaculation. He has no problem with arousal, rigitdity or penetration but achieves orgasm after 5 minutes. Which treatment is recommended?

A. Daily SSRI
B. Dapoxetine on demand
C. No treatment
D, Topical lidacain-prilocaine cream

A

C. No treatment