Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MM > Androgenic/Cholinergic > Flashcards

Androgenic/Cholinergic Flashcards

1
Q

Bethanechol

A

Muscarinic agonist, used as stimulant of GI tract and bladder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Muscarine

A

Muscarinic agonist, derived from poisonous mushroom, treatment for glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Pilocarpine

A

Muscarinic agonist, used for treatment of xerostomia (dry mouth) and glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Nicotine

A

Nicotinic agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Neostigmine

A

Anticholinesterase, used to treat lack of tone in GI tract and bladder, stimulates GI tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Physotigmine

A

Anticholinesterase, Isolated from Calabar bean, can cross blood brain barrier, treat atropine overdose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Hexamethonium

A

Nicotinic antagonist, blocks open ionic change of the nicotinic receptor in autonomic ganglia, whichever system is the predominant tone (PNS vs. SNS) will be overridden by the less predominant system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Atropine

A

Muscarinic antagonist, treatment for bradycardia, anti cholinesterase overdose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Scopolamine

A

Muscarinic antagonist, treatment for motion sickness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Epinephrine

A

Non specific agonist, Binds α1, α2, β1, β2 receptors
Route: IM or SC (b/c PO ! GI degradation by COMT & MAO)
Effects: Vasoconstriction/↑BP, ↑HR, bronchodilation
Treats: anaphylaxis, hypotension, prevents sx blood loss w/
perioperative vasoconstriction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Norepinephrine

A

Non specific agonist, Binds α1, α2, β1 receptors
Effects: ~E, but more marked ↑diastolicBP, so BRR ! ↓HR
Treats: hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Phenylephrine

A

α agonist, Binds α1 receptor
Effect: Vasoconstriction/↑BP
Treats: Hypotension, nasal decongestion, pupillary dilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Clonidine

A

α agonist, Binds α2 receptor
Effect: SympNS inhibition (CNS preganglionic synapse & presynaptic
PM postganglionic synapse) ! ↓BP
Treats: hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Brimonidine

A

α agonist, Binds α2 receptor
Effect: ↓aqueous humor production
Treats: glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Isoproterenol

A

Non-specific β agonist, Binds β1, β2 receptors
OPPOSITE OF NE
Effects: net↓BP (so BRR ! ↑HR), bronchodilation, ↓GI motility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Metaproterenol

A

Binds β2 receptor
Treats: asthma
Effect: long-acting bronchodilation w/o cardiac side effects!

17
Q

Albuterol

A

Binds β2 receptor
Treats: asthma
Effect: long-acting bronchodilation w/o cardiac side effects!

18
Q

Salmeterol

A

Binds β2 receptor
Treats: COPD
Effect: long-acting bronchodilation w/o cardiac side effects!

19
Q

Terbutaline

A

Binds β2 receptor
Treats: asthma, premature labor (↓contractions)
Effect: long-acting bronchodilation w/o cardiac side effects!

20
Q

Phenoxybenzamine

A 
α blocker, blocks α1, α2 receptors 
Irreversible, non-competitive
Effects: vasodilation = ↓BP = BRR = ↑HR
Treats: pheochromocytoma
Co-admin w/ Epi: only Epi’s β1&2
effects will work = ↓BP (“epi reversal”)
21
Q

Phentolamine

A

α blocker, blocks α1, α2 receptors
Reversible, competitive
Effects: vasodilation = ↓BP = BRR = ↑HR, histamine release

22
Q

Prazosin

A

α blocker, blocks α1 receptors
Effects: vasodilation ! ↓BP w/o ΔHR
Treats: hypertension

23
Q

Yohimbine

A

α blocker, blocks α2 receptors
Reversible, competitive, opposite of Clonidine
Effects: SympNS activation = ↑BP & ↑HR (probably blocks α2)
Treats: hypotension

24
Q

Propanolol, Timolol, Pindolol

A

Non-specific first generation β blockers
Blocks β1, β2 receptors
Short-lived pharmacological effect b/c lipid-soluble, short T1/2, & 1st pass liver metabolism
Effects: ↓HR, ↓CF = ↓BP w/ long-term use
Side effect: Bronchoconstriction (bad for asthmatics!)
Treats: hypertension

25
Q

Acebutolol, Atenolol, Metoprolol

A 
Second generation β blockers 
Blocks β1 receptors
Longer-lived pharmacological effect
Effects: ↓HR, ↓CF = ↓BP but w/o bronchoconstriction
Treats: hypertension
26
Q

Carvediol

A

Third generation β blocker
Blocks α1, β1 receptors
Effects: ↓HR, ↓CF = ↓BP + vasodilation
Treats: heart failure

27
Q

Celiprolol

A 
Third generation β blocker 
Blocks β1 receptors
Effects: ↓HR, ↓CF = ↓BP + vasodilation
Partial β2 agonist = vasodilation
Treats: heart failure
28
Q

Nebivolol

A 
Third generation β blocker 
Blocks β1 receptors
Effects: ↓HR, ↓CF = ↓BP + vasodilation
Also causes release of NO by endothelial cells = vasodilation
Treats: heart failure

MM (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions