Anatomy of the kidney Flashcards

1
Q

What sheath surrounds the kidney?

A

Renal capsule

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2
Q

What are the two major layers of the kidney

A

Renal cortex

Renal medulla

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3
Q

What is contained in the renal cortex?

A

Blood vessels, lymph and connective tissue

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4
Q

What is contained in the renal medulla?

A

Nephrons

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5
Q

What superstructure is found in the renal medulla?

A

Pyramids

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6
Q

How many pyramids do each kidney have?

A

~12

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7
Q

How many nephrons are found in a pyramid?

A

~50,000

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8
Q

What does the medulla look like?

A

Striated

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9
Q

What gives the medulla its striated appearance?

A

Nephrons

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10
Q

What does the renal medulla drain into?

A

Minor calyx

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11
Q

What do minor calyx drain into?

A

Major calyx

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12
Q

What do major calyx drain into?

A

Renal pelvis

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13
Q

What does the renal pelvis drain into?

A

Ureter

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14
Q

What occurs where the renal pelvis changes to the ureter?

A

Narrowing of pelviureteric junction

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15
Q

Name 9 major parts of the nephron

A
Glomerular
Bowman's capsule
Afferent arteriole
Efferent arteriole
Proximal tubule
Loop of Henle
Distal tubule
Collecting duct
Peritubular capillaries
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16
Q

Describe the blood flow round the nephron

A
Afferent arteriole
Glomerulus
Efferent arteriole
Peritubular capillaries
Vein
17
Q

Describe the flow of fluid once it had been filtered

A
Bowman's capsule
Proximal tubule
Loop of Henle
Distal tubule
Collecting duct
18
Q

What happens at the glomerulus?

A

Blood is filtered into the Bowman’s capsule

19
Q

Describe the route of the proximal tubule with regards to the arterioles

A

Passes between afferent and efferent

20
Q

What is found at the junction between the afferent and efferent arterioles and the proximal tubule?

A

Juxtaglomerular apparatus

21
Q

What two types of nephron do we have?

A

Juxtamedullary

Cortical

22
Q

What is the difference between juxtamedullary and cortical nephrons?

A

Juxtamedullary have longer loops of Henle

23
Q

Do we have more juxtamedullary or cortical nephrons?

A

Cortical (80%)

24
Q

Is the afferent or efferent arteriole bigger?

A

Afferent

25
Q

What forms the inner layer of the Bowman’s capsule?

A

Podocytes

26
Q

What separates podocytes from endothelium?

A

Thick basement membrane

27
Q

What special cells are found in the juxtaglomerular apparatus?

A

Granular cells

Macula densa

28
Q

How long is a nephron?

A

45-65mm

29
Q

What do cells of the proximal tubule have on their surface?

A

Many microvilli for reabsorption

30
Q

How can you tell a proximal tubule on histology?

A

Junction between lumen and cells looks fuzzy

31
Q

Do cells of the distal tubule have microvilli?

A

Not really

32
Q

Where is the proximal tubule found?

A

In the cortex between the glomerulus and corticomedullary junction

33
Q

Where is the loop of Henle found?

A

Medulla

34
Q

Where is the distal tubule found?

A

In the cortex between the medullary cortical junction and the collecting tubule.