Anatomy of the kidney Flashcards

1
Q

What sheath surrounds the kidney?

A

Renal capsule

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2
Q

What are the two major layers of the kidney

A

Renal cortex

Renal medulla

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3
Q

What is contained in the renal cortex?

A

Blood vessels, lymph and connective tissue

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4
Q

What is contained in the renal medulla?

A

Nephrons

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5
Q

What superstructure is found in the renal medulla?

A

Pyramids

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6
Q

How many pyramids do each kidney have?

A

~12

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7
Q

How many nephrons are found in a pyramid?

A

~50,000

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8
Q

What does the medulla look like?

A

Striated

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9
Q

What gives the medulla its striated appearance?

A

Nephrons

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10
Q

What does the renal medulla drain into?

A

Minor calyx

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11
Q

What do minor calyx drain into?

A

Major calyx

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12
Q

What do major calyx drain into?

A

Renal pelvis

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13
Q

What does the renal pelvis drain into?

A

Ureter

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14
Q

What occurs where the renal pelvis changes to the ureter?

A

Narrowing of pelviureteric junction

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15
Q

Name 9 major parts of the nephron

A
Glomerular
Bowman's capsule
Afferent arteriole
Efferent arteriole
Proximal tubule
Loop of Henle
Distal tubule
Collecting duct
Peritubular capillaries
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16
Q

Describe the blood flow round the nephron

A
Afferent arteriole
Glomerulus
Efferent arteriole
Peritubular capillaries
Vein
17
Q

Describe the flow of fluid once it had been filtered

A
Bowman's capsule
Proximal tubule
Loop of Henle
Distal tubule
Collecting duct
18
Q

What happens at the glomerulus?

A

Blood is filtered into the Bowman’s capsule

19
Q

Describe the route of the proximal tubule with regards to the arterioles

A

Passes between afferent and efferent

20
Q

What is found at the junction between the afferent and efferent arterioles and the proximal tubule?

A

Juxtaglomerular apparatus

21
Q

What two types of nephron do we have?

A

Juxtamedullary

Cortical

22
Q

What is the difference between juxtamedullary and cortical nephrons?

A

Juxtamedullary have longer loops of Henle

23
Q

Do we have more juxtamedullary or cortical nephrons?

A

Cortical (80%)

24
Q

Is the afferent or efferent arteriole bigger?

25
What forms the inner layer of the Bowman's capsule?
Podocytes
26
What separates podocytes from endothelium?
Thick basement membrane
27
What special cells are found in the juxtaglomerular apparatus?
Granular cells | Macula densa
28
How long is a nephron?
45-65mm
29
What do cells of the proximal tubule have on their surface?
Many microvilli for reabsorption
30
How can you tell a proximal tubule on histology?
Junction between lumen and cells looks fuzzy
31
Do cells of the distal tubule have microvilli?
Not really
32
Where is the proximal tubule found?
In the cortex between the glomerulus and corticomedullary junction
33
Where is the loop of Henle found?
Medulla
34
Where is the distal tubule found?
In the cortex between the medullary cortical junction and the collecting tubule.