Anatomy (M1) Flashcards

1
Q

The bones of the thoracic cavity: Sternum

A
  • Head AKA Manubrium: at the top, it has the suprasternal notch at T2, at the bottom it has the sternal angle at T4.
  • Body
  • Tail AKA Xiphoid Process: ends at T9/T10.
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2
Q

Features of ribs

A
  • Ribs are attached to the sternum by costal cartilage.
  • The have an external and internal surface.
  • On the internal surface they have a costal groove: this is normally where a vein, artery and nerve run.
  • The head of the rib connects to the vertebrae of the spinal column. The head has two articular facets. One attaches to the demi facets of the numerically corresponding vertebra and the other with the vertebra above. This is a costavertebral joint.
  • The tubercle which is on the neck of the rib, attaches to the facet on thr transverse process of the vertebra. This is a costotransverse joint.
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3
Q

Typical vertebrae

A
  • The spinal column is made of vertebral bodies stacked on top of each other, with intercalated discs.
  • Spinous process face downwards: so you can’t bend backwards too much.
  • Transverse process stick out sideways.
  • Neural arch refers to everything apart from the vertebral body.
  • Vertebral Foramen the hole in the vertebral body.
  • Pedicle: the arch between the vertebral body and the transverse process.
  • Lamina: the arch between the transverse process and the spinous process.
  • Superior/ Inferior Articular Process: attach to vertebra above and below.
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4
Q

How is the upper and lower respiratory system divided?

A
  • By the sternal angle = T4
  • Above T4 = upper respiartory tract (the trachea, oral and nasal cavity).
  • Below T4 = trachea bifurcates into bronchi and alveoli.
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5
Q

Pleura

A
  • Pretend the lungs grew into a baloon.
  • If your pushed your fist completely into a semi-inflated balloon, then the part of the baloon in contact with your hand is the visceral pleura.
  • The inside of the baloon is the pleural cavity, and contains pleural fluid.
  • The outside of the baloon is the parietal pleura.
  • The pleura are made of mesothelium cells.
  • You have more parietal pleural than the lungs actually fill, unless you brathe in really forcefully. This is a costodiaphragmatic recess, and is a potentiall space for fluid to collect in injury, in the ribs 8-10.
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6
Q

Describe the conducting and respiratory airways

A
  • Sections of the respiratory tract which do not participate in gas exchange.
  1. Trachea
  2. Right and Left Bronchus
  3. Lobar Bronchi (for each lobe)
  4. Segmental Bronchi (parts of each lobe)
  5. Segmental bronchi divide 13 times until get Terminal Bronchioles.

Then in the respiratory conducting system, things keep divising and we give them fancy names:

  • Respiratory Bronchioles
  • Alveolar Ducts
  • Alveolar Sacs
  • Alveoli
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7
Q

The bones of the thoracic cavity:

Superior Thoracic Aperture

A

The superior thoracic aperture simply refers to the circle formed by the bones, at the top of the thoracic cavity. It is a circle made by the sternum, the 1st ribs and spinal vertebra.

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8
Q

The bones of the thoracic cavity: Ribs

A
  • You have 12 pairs of ribs
  • The first 7 are true ribs: they have their own individual costal catilage connecting them to the sternum.
  • Ribs 8, 9 and 10 are false, because they share the same costal catrilage connecting them to the sternum.
  • Ribs 11 and 12 are free floating. This means they are not connected to the sternum.
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9
Q

Describe the trachea

A
  • Bifurcates at T4.
  • Made of c-shaped rings of cartilage.
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10
Q

How many lobes does each lung have?

A
  • Right lung has three lobes.
  • Left lung has two.
  • Lobes are made when the visceral membrane is doubled and seperates them by invaginating them.
  • The lobe fissures can be seen on the anterior side of the lungs.
  • The left lung only has the oblique fissure, which slices the lungs from the middle of the back of the lungs, to the corner of the front of the lungs.
  • The right lung also has a horizontal fissure in the middle.
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11
Q

What does the hilum of the lungs allow in and out?

A
  • Bronchi in
  • Pulmonary artery in
  • Pulmonary vein out
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12
Q

What surface markings do each lung have on their posterior side?

A

Left Lung:

  • Cardiac Impression
  • Aortic Impression
  • Lingula

Right lung:

  • Cardiac Impression
  • Azygos Vein
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13
Q

The clinical relevance of pleura

A
  • Pneumothorax: more air in pleural cavity- collapsed lung.
  • Pleural Effusion: fluid in cavity
  • Haemothorax: blood in cavity
  • Chylothorax: lymph in cavity
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14
Q

Describe the cell types in the last part of the conducting airways

A
  • We have bronchioles and then terminal bronchioles at the end of the conducting airways.
  • Bronchioles are made of pseudostratified, simple columnar epithelium.
  • Terminal bronchioles are made of low columnar ciliated epithelia, and have less goblet cells.
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15
Q

What does lamina propria do?

A

A capillary in the conducting portion that warms air.

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16
Q

What are basal cells?

A

Rounded cells, near basal lamina, stem cells, mitotic.

17
Q

What do goblet celld do?

A

Mucus secretion

18
Q

Describe the histology of the bronchus

A
  • The lumen of the bronchus is folded (not a perfect circle) and is made of ciliated pseudostratified columnar epithelium.
  • The mucosa is seen as white blobs and contains goblet cells to secrete mucas.
  • Smooth muscle looks smooth.
  • Cartilage plate is darker than smooth muscle, and has little blobs in it.
  • There are serous glands too.
  • As branching continues through the bronchial tree, the cartilage decreases, and the amount of smooth muscle increases.
19
Q

Difference between bronchi and bronchioles?

A

The bronchi when too narrow to be supported by cartilage are known as bronchioles.

20
Q

Bronchus cell types?

A
  • Bronchus:
    • Pseudostratified, ciliated, columner epithelium
    • Mucosa layer
    • Thick lamina propria
    • Cartilage
    • Smooth muscle
    • Serous (fluid cells)
    • Goblet cells
    • Basal/ stem cells
21
Q

Segmental bronchi cell types?

A
  • Segemental Bronchi:
    • Tall columner epithelium
    • Thin lamina propria
    • Less cartilage
    • More smooth muscle
    • Less goblet cells
22
Q

Conducting bronchioles cell types?

A
  • Low columner epithelium or ciliated cuboidal cells
  • Clara cells
23
Q

Respiratory bronchioles cell types?

A
  • Ciliated cuboidal cells
  • Clara cells
  • Remember bronchioles have no goblet cells or cartilage
24
Q

Alveolar ducts and sacs cell types?

A
  • Squamous cells (T1/ flat and T2/ round pneumocyte)
  • No cilia
25
Q

Alveous cell types?

A
  • T1/ flat pneumocytes
  • T2/ rounds pneumocytes
  • Share basal lamina/ base with endothelial cells so thinner barrier for gas exchange.
  • Has no connective tissue.
26
Q

What is the pulmonary interstitum?

A

Tissue in the alveolar septum that is between two layers of alveolar epithelium and bounded by visceral pleura. The part of the lung between the epithelial and endothelial basement membrane.

  • Contains:
    • Capillaries
    • Lymphocytes
    • Mast cells
    • Connective tissue
    • Fibroblasts
    • Elastic fibres
    • Collagen fibres
27
Q

How does quiet and forced respiration happen?

A

Quiet Respiration: due to movements of thoracic wall, abdomen, but mostly diaphragm

Forced Respiration: accessory muscles of respiration and abdominal muscles assist

28
Q

Describe the articulation of the ribs with vertebrae and sternum to cause expansion of the thoracic cavity

A
  • Bucket handle movements make the thorax expand sideways (laterally). The rib shafts are pushed up., increasing volume.
  • Pump handle movements cause the sternum to move up and out, This makes the thorax longer, thereby increasing volume of the thorax.
29
Q

Respiratory Muscles

A
  • Diaphragm
  • Intercostal muscles:
    • External
    • Internal
    • Inner-most
  • Abdominal wall muscles:
    • Rectus abdominis
    • Transversus abdominis
    • Obliques
  • Accessory Respiratory Muscles
    • Sternocleidomastoids
    • Scalenes
    • Pectoralis minor
    • Quadratus lumborum
30
Q

Which muscles do we use in inspiration?

A

•Diaphragm

•External intercostals

•Accessory muscles:

Sternocleidomastoids

Scalenes

Pectoralis minor

Quadratus lumborum

31
Q

Which muscles do we use in expiration?

A
  • Internal intercostals
  • Abdominal muscles
32
Q

Describe the intercostal muscles

A
  • Intercostals serve to keep intercostal space rigid to prevent IC spaces being blown out during expiration or in during inspiration.
  • 60% slow-twitch fibres - high capacity for aerobic metabolism and endurance
  • The external intercostals are between ribs, so there are 11 pairs of them. Elevate ribs and keep inter-costal space rigid.
  • The internal intercostals are also 11 pairs. They are from the floor of the costal groove to rib above. They depress ribs and keep ICS rigid.
  • Innermost layer: continous subcostal and transverse thoracic.
33
Q
A
34
Q

The diaphragm

A
  • Contracts and flattens, which increases thoracic volume and draws air into the lungs.
  • Separates the thoracic and abdominal cavities
  • Increases intra-abdominal pressure, helping to expel vomit, faeces, and urine
  • Preventing acid reflux by exerting pressure on the oesophagus as it passes through the esophageal hiatus.
  • Dome-shaped skeletal muscle
  • Superiorly attatched to the central tendon and fibrous pericardium
  • Inferiorly attatched to the costal margin, lumbar vertabrae and posterier abdominal wall.
  • There is a right crus and a left crus which are used to tether the diaphragm for contraction.
  • There are three arcuate ligaments: Median (aorta) Medial (psoas major) Lateral (quadratus lumborum)
  • Has three openings:
    • The caval opening at T8 for the inferior vena cava and right phrenic nerve.
    • The oesophogeal hiatus at T10 for oesophogus and its blood vessels and the vagal trunks.
    • The aortic hiatus at T12 for the aorta, thoracic duct and azygous vein.
  • The diaphragm is innervated by the right (caval opening) and left phrenic nerve (through the diaphragm itself). The phrenic nerve is a nerve that originates in the neck (C3-C5) and passes down between the lung and heart to reach the diaphragm. It is important for breathing, as it passes motor information to the diaphragm and receives sensory information from it. A marginal part is innervated by spinal nerves T6-12 (sensory). Crura innervated by spinal nerves from T12.