Anatomy H&N Flashcards
Describe the the thyroid gland:
Function: Largest endocrine gland (also encompasses the histologicaly and functionally distant parathyroid), producing thyroid hormones (T3 & T4, metabolism) and calcitonin (Ca and PO4 homeostasis).
Appearance: Described as butterfly shaped due to two lobes either side of the midline of the neck, joined by an isthmus. There is often a pyramid of gland directed superiorly from the left or right lobe.
Position/Size: Spans C5-T1. Lies inferior to the thyroid cartilage and is encapsulated by a fibrous capsule which fuses the gland to the cricoid cartilage.
Capsule is enclosed in a loose sheath formed by the pretracheal layer of the deep cervical fascia.
Lies deep to sternothyroid and sternohyoid muscles
Right and left lobes anterolateral to the larynx and trachea
In close contact with the small parathyroid glands which are posterior.
The fibrous thyroid capsule lies within?
The pre tracheal layer of the deep cervical fascia.
Which is more superficial, the sternohyoid or sternothyroid muscle?
The sternothyroid is deeper as it attaches to the inferior edge of the thyroid cartilage, the sternohyoid passing over on its way caudal to the sternum.
Microscopic description of the thyroid:
● Numerous lobules comprising individual follicles
● Supporting stroma and vasculature
● Follicles consists of single layer of cuboidal surface epithelium comprising thyroid follicular cells surrounding a central lumen containing colloid
● 10% of follicular epithelium contain parafollicular C cells, neural-crest derived containing granules of calcitonin
What makes calcitonin? Where
Parafolicular C cells make up 10% of the surface cuboidal cells surrounding colloid.
Follicular cells secrete? Stimulated by what and from where?
Follicular cells secrete thyroglobulin (contains iodine), T4 (storage and transport form), and T3 (active form)
Stimulated by TSH from anterior pituitary
Relations of the thyroid gland:
Relations
● Anterolaterally: sternothyroid, sternohyoid, superior belly of omohyoid and SCM
● Posterolaterally: carotid sheath and contents: common carotid, IJV, vagus nerve
● Medially: larynx and trachea, pharynx and oesophagus, recurrent and superior laryngeal nerves
● Posteriorly: parathyroid glands, vertebral bodies
Arterial supply to the thyroid
Arteries lie between the fibrous capsule and loose fascial sheath
1) Superior thyroid artery = anterior and superior
■ branch of external carotid
2) inferior thyroid artery = Posterior and inferior
■ branch of the thyrocervical trunk from 1st part of the subclavian artery
In 10% people isthmus is supplied by the Ima artery, a branch of brachiocephalic
Venous drainage of the thyroid:
The 2 paired (superior and middle thyroid veins) and 1 unpaired (Inferior thyroid vein) form a venous plexus.
The Sup and middle drain to the IJV, the inferior to the brachiocephalic trunk.
Any exam question about the lymphatic drainage of the thyroid should begin with:
Lymphatic vessels in the interlobar connective tissue and capsule.
Lymphatic drainage of the thyroid:
Lymphatic vessels in the interlobar connective tissue and capsule are multidirectional complex and extensive. Drains initially into peri-thyroid nodes, somewhat ipsilaterally drain to: Pre laryngeal (midline so bilaterally to) -> superior deep cervical nodes Pre tracheal (midline so bilaterally to) -> inferior deep cervical nodes ***** Para tracheal (lateral so drain ipsilaterally) -> Inferior deep cervical nodes, supraclavicular nodes and upper mediastinal nodes
Relations between structures in the carotid sheath:
IJV lateral to common carotid, vagus posteriorly.
Deep carotid nodes lie on the anterior lateral surface of the IJV.
Course of the Right common carotid
Right: Branches from the bifurcation brachiocephalic trunk behind the sternoclavicular joint. Ascends in the neck along with the other structures in the carotid sheath until it bifurcates into external and internal branches at the SUPERIOR BORDER of the Thyroid cartilage where the External leaves the sheath on its more anterior course.
Course of the Right common carotid
Left. Arises from the aortic arch immediately before the left subclavian artery, Travels 2cm superiorly in the superior mediastinum before entering the neck posterior to the Left sternoclavicular joint. Ascends in the neck along with the other structures in the carotid sheath until it bifurcates into external and internal branches at the SUPERIOR BORDER of the Thyroid cartilage where the External leaves the sheath on its more anterior course.
Where does the external carotid artery begin and end?
Begins at the bifurcation of the common carotid at the superior border of the thyroid cartilage.
End when divides into terminal branches = maxillary artery and superficial temporal behind neck of mandible.
Major Branches of the external carotid arteries:
1) (Almost immediately) Ascending laryngeal (gives off laryngeal branches)
2) Superior thyroid
3) Lingual
At the same level 4) & 5)
4) Facial artery, dips to medial side of angle of mandible to give off ascending palatine and tonsillar branches. Then rises superficial to the body turning superiorly to become the angular artery.
5) Occipital artery
6) Posterior auricular artery
The end at bifurcation into Terminal branches (post to neck of mandible:
Maxillary artery - to ptygopalantine fossa
Superficial temporal
The internal carotid begins at what vertebral level? and can be divided into how many segments:
A more complex division:
Begins at C4. 4 segments: Cervical (continues in sheath w/o branches) Petrous Cavernous Cerebral
Bouthillier's divisions (surgical and radiological use) are in to 7. In the scheme above (no cerebral): Cervical Petrous ** Lacerum Cavernous ** Clinoid ** Ophthalmic ** Communicating
Mnemonic for the internal carotid artery:
Conservative Politicians Love Compliant Cattle Over Complex arguments
Cervical Petrous Lacerum Cavernous Clinoid Ophthalmic Communicating artery.
The cervical segment of the internal carotid ends at (what is anterior):
Describe the 1st part of common carotid
C1 ends at carotid canal posterior to JV
Bulges after origin (the carotid sinus/bulb)
Course of cervical Internal carotid:
Ascends anterior to transverse processes of C1-3
Deep to parotid gland and internal jugular vein
Lateral to pharynx
Enters cranial cavity through carotid canal.
At the base of the skull what lies between the jugular vein and the internal carotid?
At the base of the skull the glossopharyngeal, vagus, accessory, and hypoglossal nerves lie between the artery and the internal jugular vein.
Describe C2 and C3 of the internal carotid:
Petrous (C2) Lacerum (C3)
○ Extends to foramen lacerum
○ Ascends in the carotid canal in petrous temporal bone
○ curves forwards and medially
○ then upwards and medially above foramen lacerum
○ Related posteriorly with cochlea and tympanic cavity
○ ***** superiorly with trigeminal ganglion
○ Surrounded by carotid plexus of nerves (sympathetic)
○ Branches: caroticotympanic and pterygoid
Describe C4 and C5 of internal Carotid
Cavernous (C4) + Clinoid (C5) = Cavernous segment
Curves layers of the dura mater forming the cavernous sinus (covered by the lining membrane of the sinus):
- First ascends toward the posterior clinoid process,
- Then passes forward by the side of the body of the sphenoid bone,
- again curves upward on the medial side of the anterior clinoid process, and
- perforates the dura mater forming the roof of the sinus. The curve in the cavernous segment is called the carotid siphon.
This portion of the artery is medial to abducent nerve (VI)
The crinoid segment is a tiny little bit with no branches betten the cavernous sinus and where the artery enter sub-arachnoid space/
Describe the ophthalmic segment of the internal carotid
○ After perforating dura medial to the anterior clinoid process
○ Curves backwards below optic nerve
○ Passes between optic and oculomotor nerves
○ Divides into anterior and middle cerebral arteries and join the Circle of Willis
○ Branches: ophthalmic, anterior cerebral, middle cerebral, posterior communicating, anterior choroid.