Anatomy And Physiology Flashcards
Superior
Top
Inferior
Below
Anterior/ ventral
Front
Posterior/dorsal
Back
Caudad
Tail
Medial
Away from side
Cephalad
Head
Lateral
Side
Distal
Away from point of origin
Proximal
Close to point of origin
Visceral
Internal organs
Parietal
Toward wall
- away from outer wall
Deep
Inside of part
-away from surface
Superficial
Toward surface of part
-away from inside
Medullary
Inner region, medulla
Cortical
And utter region, cortex
Adduction
Toward
Abduction
Away from
Afferent
Movement the toward center
Circumduction
Drawing an imaginary circle
Efferent
Movement away from center
Eversion
Turn outward
Extension
Movement of limb into straight position
Flexion
Movement limb bent
Inversion
Turn inward
Plantar flexion
Point toe downward
Prone
Lying straight on ones frontside, face down
Supine
Lying straight on ones back, face up
A, an
Without, absence
Ab
Away from
Ad, af, ap, as, at
Toward, in direction of
Ana
Excessive
Bi
2, life
Bin
2 by 2
Brady
Slow
Dia
Through, complete
Dipl
Double, twin
Dys
Bad, difficult, painful
Endo
Within
Epi
On
Eti
Cause
Eu
Good, normal, easy, well
Ex, exo
Outside, outward
Hemi
Syn, sym
Hyper
Excessive, increase
Hypo
Deficient, decrease
Inter
Between, amount
Intra
Within, inside
Meta
Change, after, beyond
Neo
New
Nulli
None
Pan
All, total
Para
Beside, beyond, around
Per
Through
Peri
Surrounding
Poly
Many
Post
After
Pre
Before
Sub
Under, less, below
Super, supra
Above, excessive
Syn, sym
Together, join
Ectasis
Stretching out, dilation, expansion
Ectomy
Surgical removal
Emia
Blood condition
Emesis
Vomiting
Gen
Agent that causes or produces
Genesis
Origin, cause
Genic
Producing, causing, originating
Gram
An instrument for recording, picture, record
Graphy
Process of producing a picture
Ia
Diseased, abnormal condition
Iasis, esis
Condition
iatry
Physician, treatment
ical, ial, ic, ior
Pertaining to
ictal
Seizure, attack
Lysis
Loosening, dissolution, separating
megaly
Enlargement
meter
Instrument to measure
Metry
Measurement
Necrosis
Tissue death
Odynea
Pain
Oid
Resembling
Ologist
specialist
ology
The study of
oma
Tumor
Opia
Vision
Opsy
To view
Ory, ose, ous
Pertaining to
Osis
Abnormal condition
Ostomy
Surgically created opening
Otomy
Surgical incision
Oxia
Oxygen
Paresis
Slight paralyzed
Pathy
Disease
Penia
Abnormal reduction in number
Pepsia
Digestion
Pexy
Surgical fixation, suspension
Phagia
Eating, swallowing
Phobia
Abnormal fear, aversion to
Phonia
Sound, voice
Physis
Growth
Plasia
Formation
Plasm
Formative material of cell
Plasty
Surgical repair
Plegia
Paralysis
Pnea
Breathing
Poiesis
Formation
Ptosis
Drooping, sagging, prolapse
Rrhage, rrhagia
Bleeding, bursting forth
Rraphy
Surgical suturing
Rrhea
Flow, discharge
Rrhexis
Rupture
Sarcoma
Malignant tumor
Schisis
Split, fracture
Scope
Visual exam with instrument
Scopy
Visual examination
Sis
State of
Spasm
Sudden involuntary muscle contraction
Stasis
Control, maintenance at constant level
Stenosis
Abnormal tightening, narrowing
Tome
Instrument used to cut
Tripsy
Surgical crushing
Trophy
Development
Thorax
Chest
Uria
Urine, urination
Carcin
Cancer
Chrom
Color
Cyan
Blue
Cyt
Cell
Erythr
Red
Gno
Knowledge
Hist
Tissue
Kary
Nucleus
Lei
Smooth
Leuk
White
Lip
Fat
Melan
Black
Neur
Nerve
Onc
Tumor
Organ
Organ
Path
Disease
Rhabd
Rod shape or striated
Sarc
Flesh, connective tissue
Somat
Body
Viscer
Internal organs
Xanth
Yellow
Atom
Smallest chemical unit of matter
Molecule
Combination of 2 or more atoms, to make the smallest unit of substance.
Element or compound. Can be substance.
Water molecule made up of 2 hydrogen atoms and 1 oxygen atom
Cell
Basic unit of life, building block for tissue, organs
Mitosis
Division of 1 cell into 2 identical cells
Meiosis
Division of sex cell for organism, sexually produced
Active transport
Movement of molecule from area of high concentration to low.
Made possible because adenosine triphosphate:high energy compound
Diffusion
Passive movement of dissolved particles by membrane from high concentration to low.
More common transport mechanism
Filteration
Use of mechanical pressure to diffuse liquid through membranes.
Form of passive transport
Osmosis
Type of diffusion, movement of water or other substance in solution pass semipermeable membrane.
Membrane allow some substance to pass through.
Form of passive transport
Passive transport
No cellular energy required to move water and dissolve substance
Phagocytosis
Ingest and digest substance by phagocytosis cell.
Require cellular energy
Tissue
Group of cells perform specific functions
Organ
Organ is body structure made up of a group of tissue, serve a common purpose or function
Epithelial tissue
- skin, tube ducts, some glands, lining of cavity
- protects, absorb, secretes, excretes
Connective tissue
- bone, cartilage, tendon, muscle, sheaths, cardiac
- support, connect, other tissue and structure
Muscle
- striated, smooth, cardiac
- movement, contracts, shortens
Nerve
- Neurons in cells throughout body
- actively transmits impulse through networks
Systems
Group of organs work together to perform specific function
Homeostasis
Equilibrium, maintenance a balance of internal body. Maintain in healthy state
Smallest bone of body
Ear bones
-malleus, incus, stapes
Spine column
-cervical: C1-C7, curve inward —atlas:C1, move head up/down —axis: C2, move head side to side -thoracic: T1-T12, curve outward -lumbar: L1-L5, curve inward -sacral: 5 fused vertebrae, curve outward -coccyx: 4 fused vertebrae
Thorax
Rib cage
- sternum: breastbone
- xiphoid process: small, flat, blade like bone tip at bottom
- ribs: 12 pairs
Humerus
Upper arm, largest arm bone
Radius
Lower arm, thumb side
Ulna
Lower arm, little finger side
Carpals
Wrist bones
Metacarpals
Hand bones, palm
Phalanges
Fingers and thumb bones
Femur
Thigh bone
-largest, longest, strongest bone
Greater trochanter
Knob at top of femur
Patella
Kneecap
Tibia
Shin bone
-largest lower leg bone
Fibula
Lower leg, lateral side of leg
Tarsal
Ankle bone
Calcaneus
Heel bone, largest of tarsal
Metatarsals
Foot bone
Phalanges
Toe bones
Scapula
Shoulder blade, upper back bone
Clavicle
Collarbone, anterior shoulder bone
ilium
Winged shape portion of pelvic
ischium
Inferior portion of hip, sit support
Pubis
Anterior Union f hip
Sacrum
Posterior wall of pelvis
5 fused bones
Coccyx
Tail bone
-4 fused small vertebrae and ligament
Synarthrosis
Immovable.
2 bones separated only by membrane
Amphiarthrosis
Slightly movable.
Fibrocartilaginous disk joined by joint capsule, contain synovial fluid for lubrications
Enarthrosis
Ball and socket.
Joint allow wide range of motion: flexion, extension, abduction, adduction, rotation, circumduction
Condyloid
Joint allows all form of angular movement except axial skeletal rotation
Arthrodia
Gliding
-joint permit single bony surface to slide on another, simple motion only
Ginglymus
Hinge
-joint only has single forward and backward motion: flexion and extension
Trichoid
Pivot
- joint allow rotation of bone
- C1, C2
Saddle
Opposing surface reciprocally concavoconvex movement: flexion, extension, abduction, adduction, circumduction
Bursa
Fibrous sac, acts as cushion to ease movement
Condyle
Large round knob, usually fits with another bone
Crest
Ridge on bone
Foramen
Hole in bone serving as passageway for vessels, nerves
Fossa
Depression or groove in bone
Periosteum
Thick fibrous membrane covers bone surface, except articulated cartilage
Process
Prominent projection on bone
Synovial fluid
Lubrication fluid for joints, bursae, tendons.
Make smooth movement of joints
Arthrocentesis
Puncture performed to remove fluid for pressure pain relief or analysis
Arthroscopy
Procedure to view internal structure of joint, providing surgical access
Laminectomy with spinal fusion
Procedure to stabilize vertebra by remove part of it
Traction and reduction
Procedure performed to realign bone
Xray
Radiograph of bone to examine for breaks or density
Cleft palate
Congenital deformity occurs when palatine bones improperly close
Closed fractures
Simple, do not break skin
Green stick fracture
Incomplete
Spiral
Twist break of bone
Compound
Open, complete break through skin
Comminuted
Bone shattered to 3 or more fragments
Impacted
Broken ends forced into one another
Gout
Pain in great toe and other body joints
-condition v build u of crystallize uric acid result from high purine metabolism and other symptoms
Kyphosis
Abnormal outward curvature, hunchback
Lordosis
Abnormal inward curvature of spine, swayback
Osteoarthritis
Inflammation of joints
Osteomalacia
Softening and deformation of bone, cause by vitamin D deficiency
- loss of calcium, phosphorus
- rickets in children
Osteoporosis
Bone mass reduction. Bone become thin, porous, easily fracture
Osteitis deformans
Paget disease
-abnormal weakened bone formation cause by excessive breakage of bone tissue
Phantom pain
Feeling of sensation in absent, amputated limb
Rheumatoid arthritis
Autoimmune disease, cause painful and swelling joints,result in deformities
Scoliosis
Lateral, sideward curvature
Spondylosis
Inflammation of 1 or more vertebrae
Sprain
Injury to joint (wrist, knee, ankle) result in stretch or torn ligament
Cost
Rib
Arthr
Joint
Ankyl
Crooked, stiff, bent
Chondr
Cartilages
Kinesi
Movement or motion
Lamin
Laminate
-thin, flat plate or layer
Smooth muscle
Visceral
- involuntary
- within walls of hollow organs
- contraction cause movement (peristalsis)
Skeletal
Voluntary
- attach to bones
- striated
Cardiac
Involuntary
- walls of heart
- all cells work together for rhythmic cell pulse
- striated
Tendons
Connective
-attach to muscles to periosteum of bone
Ligaments
Attach bone to bone
Biceps
Upper arm bender or flexor
Deltoid
Upper shoulder and arm
Gluteus medius
Buttock
-upper outer quadrant (injection at dorsogluteal or ventrogluteal site)
Masseter
Principal muscle in mastication
Pectoralis major
Chest
Triceps
Upper arm
-straightener or extensor
Vastus latealis
Upper outer thigh (common for infant injections)
Aponeurosis
Broad covering sheet of fibrous connective tissue that binds muscle to muscle or muscle to bone
Gnoiometry
Measure joints movement and angle
Manipulation
Procedure examines range of motion
-used in physical therapy
Atrophy
Muscle wasting result from lack of use
Bursitis
Inflammation of bursa
Cramp
Painful involuntary contraction by skeletal muscle
Epicondylitis
Inflammation of forearm tendons
Fibromyalgia syndrome
Debilitating chronic condition characterized by specific or widespread muscle, bone, joint pain, fatigue and other symptoms
Muscular dystrophy
Genetic disease characterized by wasting of skeletal muscles
Myasthenia gravis
Autoimmune neuromuscular disease cause by abnormal transmission of nerve impulse, result in muscle fiber atrophy or shrinkage, inhibits normal movement, extreme muscles weakness
Sprain
Injury of ligaments around joint are torn but not severed
Tendonitis
Inflammation of tendons
Bursa
Sac, cavity
Fibr
Fibrous connective tissue
Ten, tend, tendin
Tendon
My, myos
Muscle
Heart
- located within pericardium
- outer layer of sac: parietal pericardium
- inner membrane: visceral pericardium
- 4 chambers: 2 atria, 2 ventricles
- blood passes through hollow heart muscle
Interventricular septum
Wall of tissue divides heart in half vertically
Aortic semilunar valve
Valve opens to allow oxygen rich blood to flow out of left ventricle into aorta, carry blood throughout body
Mitrial valve
Bicuspid
-close opening between left atrium and left ventricle to prevent back flow
Pulmonary semilunar valve
Valve opens to allow poor oxygen blood to flow out of right ventricle and into pulmonary arteries
-carry blood to lungs
Tricuspid valve
Close opening between right atrium and right ventricle to prevent back flow
Arteries
- transport blood away from heart
- have thickest muscled vessel walls
- rich with oxygen saturation
Coronary artery
Supply blood needed for cardiac muscle to function
Aorta
Carry oxygen rich blood from left ventricle of heart
-largest and thickest wall artery of body
Carotid artery
Located on either side of neck
- carries blood upward to head
- common pulse site
Brachial artery
Located inside elbow
- carry blood from axillary artery to radial and ulnar arteries
- used for blood pressure readings
Radial artery
Located on thumb side of wrist
- carry blood to hands
- commonly used pulse site
Femoral artery
Located inner upper thigh
- carry blood from inguinal ligament, branches, then terminates at popliteal artery
- used for pulse site
Arterioles
Downsized arteries, have thinner walls of muscle
-connect arteries to capillaries
Veins
- contains many valves to prevent blood back flow
- transport blood to heart
- poor oxygen saturation, except pulmonary vein
- pulmonary vein enters atrium on left side of heart with oxygen rich blood from lungs
Vena cava
Vein receives blood from upper (superior vena cava) and lower (inferior vena cava) branches and transport to right atrium
Median cubical, cephalic, basilic veins
- Drain blood from forearm and hand
- most common sites for venipuncture, most common is median cubical vein, 2nd cephalic, 3rd basilic
- all located in antecubital fossa
Venules
Small, thin veins connect larger veins to capillaries
Capillaries
- 1 cell layer thick
- allow for exchange of nutrients and waste products through body
Blood
- type of connective tissue made of cellular components and plasma
- transport waste and nutrients products from body tissue
- blood cellular component consist of RBC, WBC, and platelets
- plasma liquid portion
- formed in red bone marrow
Red blood cells
RBC
- biconcave cells
- no nucleus
- contains hemoglobin
- live 120 days, carry oxygen and carbon dioxide
- average count 5 million per cubic millimeter
Platelets
- thrombocytes,
- cell fragments help blood clot
- average count 200,000 per cubic millimeter
White blood cells
-5 types fight invading pathogens
Arteriogram
Test is X-ray of arteries
Blood pressure reading
Diagnostic measurement performed to determine force of blood against artery walls
Electrocardiogram
Printed tracing of cardiac rhythm
Stress test
Measure heart activity during physical activity
Pulse pressure
Measurement used by finding difference between systolic and diastolic BP readings
Anemia
Abnormal low hemoglobin, RBC in blood stream
Angina pectoris
Severe chest pain cause by low oxygen supply to heart muscle
May result from stress or activity
Aneurysm
Outpouching of weakened blood vessel wall, may cause trauma or may be genetic
Arteriosclerosis
Hardening, thickening, loss of elasticity in artery wall
-most common: atherosclerosis
Atherosclerosis
Disease of arteries cause by calcium and cholesterol plaque buildup on artery wall
-restrict blood flow
Bradycardia
Slow cardiac rhythm, less than 60 bpm
Congestive heart failure
Weakening of heart ability to pump blood effectively to meet body needs.
Cause pulmonary edema
Claudication
Circulation problem of arms, legs points to vascular disease
-symptoms: limp and calf pain while walking, subside at rest
Heart block
Heart electrical conduction from sinatrial node to atrioventricular node is interrupted
Hemophilia
Occur when blood has inability to coagulate properly.
Patient lacking essential clotting factors
Hypertension
High blood pressure: greater than 140/90
Ischemia
Temporary drop in blood flow to organ or tissue
Leukemia
Uncontrolled leukocyte production invades blood cell-producing bone marrow.
Blood cancer
Murmur
Sound resulting from blood flow turbulence, narrowed or deformed valve
Myocardial infarction
Heart attack, result in lack of oxygen, some cardiac muscle necrosis occurs
Phlebitis
Painful inflammation of vein, cause by venous infection, thrombosis, or intravenous fluid irritation
Rheumatic heart disease
Damaged coronary valve resulting from rheumatic fever brought on by untreated streptococcal upper respiratory infection
Sickle cell anemia
Abnormal hemoglobin result in crescent shaped RBC. Readily stick to capillary walls. Hereditary.
Symptoms” anemia, pain cries, extremity numbness, swelling, fainting and fatigue
Tachycardia
Rapid cardiac rhythm, greater than 100 bpm
Thrombosis
Blood clot formation.
Piece of thrombus may break off and travel through blood vessels: embolus.
embolus may lodge in lungs: pulmonary embolism.
Or in brain result a stroke: cerebrovascular accident, transient ischemic attack
Varicose vein
Distended and twisted veins.
Found in superficial veins of legs, cause by long periods of standing over time.
May be seen as anal hemorrhoids
Angi
Vessels
Ather
Yellowish, fatty plaque
Cardi, coron
Heart
Isch
Deficiency, blockage
Phleb, ven
Vein
Sphygm
Pulse
Ech
Sound
Lymph
Is tissue formed from plasma.
Composed of water electrolytes, metabolizing cell waste and protein
Lymphocytes
- WBC formed in red bone marrow
- mature within spleen, liver, lymph nodes to trap and destroy microorganisms and fight against pathogens.
- nongranular
T cells
Mature in thymus and reside in lymph tissue (spleen) and blood.
Attack though cell to cell contact: phagocytosis (cell mediated immunity)
B cells
Mature in bone marrow and reside in lymph tissue (spleen) and blood.
B cells indirectly attack by secreting antibodies (antibodies mediated immunity)
Lymph node
- pea shape clusters of lymph tissue, filter microorganism from lymph as flows through lymph tissues
- large clusters location: axillary lymph nodes, inguinal lymph nodes, cervical lymph nodes
Lymph vessels
- form an extensive network, every organ has them
- lymph from right arm and right side of head drains into right lymphatic duct
- lymph flows from rest of the body drains into thoracic duct
Spleen
- largest lymphoid organ
- filters blood and serves as blood reservoir
- organ destroys old RBCs, has a role in erythropoiesis
Tonsil
- 3 pairs
- palatine: located at opening of oral cavity, usually removed in tonsillectomy
- pharyngeal (adenoids): located near opening of nasal cavity in upper pharynx, removed when interfere with breathing
- lingual: located back of tongue
Thymus
- mostly active in development of immune system during early life
- produce thymosin for maturation, function of T-cell lymphocytes
Allergy testing
Method used include: scratch test, patch test, intradermal test and radioallergosorbent test
Complete blood count
Test profile include: hemoglobin, hematocrit, RBC, WBC count
Enzyme-linked immunosorbent assay (ELISA)
Screening test for HIV antibodies presence performed on venous blood and oral fluid sample
-85% accurate due to cross-activity from other virus
Liver function
Test measure coagulation factors of prothrombin and fibrinogen
WBC differential
Blood test to determine percentage of different type of leukocytes present.
Change during infection, allergic response and certain disease
Western blot
Test specific to individual viruses and is performed to confirm diagnosis when positive result from ELISA for HIV is found
Allergies
Hypersensitive, result in inflammation may be delayed or immediate to substance not usually recognize as foreign
Autoimmune disorder
Immune system produce antibodies against its own cells.
Affect most body systems
Immunodeficiency disease
Congenital or acquired: immune system is incompetent or deficient
Severe combined immunodeficiency (SCID)
Congenital
Children succumb to minor infections
Acquired immunodeficiency syndrome
Most advance stage of infection with HIV virus.
Characterized by significant decrease in immunity evidence by low T-cells count
Systemic lupus erythematosus (SLE)
- Autoimmune disorder.
- Affects few or many organs, more woman then men
- actual cause is unknown, may be drugs or bacterial infection
- symptoms: body ache, weight loss, butterfly rash on face, sensitive to sunlight, nosebleed and seizures
Lymphoma
Benign or malignant tumors affecting lymphoid tissue`
Hodgkin lymphoma
Malignancy with enlarge spleen and lymphocytes (Reed-sternberg cells)
-occur in young men
Non-Hodgkin lymphoma
Alll lymphomas other than Hodgkin lymphoma
- may be fast or slow growing
- malignancy found throughout lymph tissue
- occur in older adult
Mononucleosis
Highly contagious viral infection
-kissing disease
From epstein-Barr virus, cytomegalovirus
-extreme fatigue, fever, sore throat, enlarge spleen and lymph tissue
Splenomegaly
Enlarge spleen associated with infectious disease
Lymph
Lymph
Spleno
Spleen
Thym
Thymus
Mouth
- Oral cavity, mechanical and chemical digestion starts
- act of mastication mix food with saliva to form bonus
- tongue has frenulum lingual: tissue anchors tongue to mouth floor
Pharynx
- throat
- pass formed bonus to esophagus
Esophagus
-food tube between pharynx and stomach
Epiglottis
Flap of tissue covers larynx (wind pipe) when swallowing, so bolus enters esophagus
Peristalsis
Involuntary rhythmic movement begins at esophagus, moves first bolus then chyme through digestive tract
Stomach
- Consist of following: esophageal sphincter, fundus, body, pylorus, pyloric sphincter
- Stomach wall composed of rugae folds to allow to expand
- mix food with gastric acid and digestive enzymes to form chyme
- secretes gastric hormones and intrinsic factor, assists in absorbing vitamin B12
Small intestine
- most absorption of nutrients take place here, by circular folds in wall with finger like projections (viili)
- longest portion: divided into 3 regions: duodenum, jejunum, ileum
Large intestines
- largest absorbs water and stores material until eliminated
- no digestion takes place here
Liver
- Produce bile and cholesterol
- store glycogen and vitamin B12, A, D, E, and K
- detox blood and aids metabolism
Gallbladder
Stores and secrete bile, aid in digestion and emulsifiers fats
Pancreas
-exocrine organ
—produce pancreatic juice for digestion
-endocrine gland
—secrete insulin into bloodstream
Colonoscopy, sigmoidoscopy, proctoscopy
Procedure perform to view parts of large intestine
Lower gastrointestinal series
Procedure use barium enema to enhance xrays of lower GI
Upper GI series
Procedure use barium swallow to enhance X-ray
Ultrasonography
Procedure use to produce image of gallbladder and bile duct
Anorexia
No appetite, aversion to food
-especially when condition caused by disease
Anorexia nervosa
- Voluntary starvation, excessive
- false perception of body image and fear of gaining weight
Appendicitis
Inflammation of appendix possible cause by blockage by feces, tumor or infection
-the McBurney point: site of tenderness associated with appendicitis
Botulism
Illness cause by toxin from clostridium botulinum usually from ingesting contaminated food
Cholelithiasis
Gallstone
- hard mineral deposit formed in gallbladder and bile ducts
- painful, vomiting and mild jaundice
Cirrhosis
End stage of liver disease, chronic liver cell destruction
Colitis
- Inflammation of colon
- affects only innermost lining, not deep tissues
Crohn disease
Chronic autoimmune inflammatory bowel disease, usually in ileum.
Penetrates every layer of tissue in affected area
Diverticula
Abnormal pouching of organ walls, usually colon
Hemorrhoids
Dilated, inflamed, varicose veins in rectum or anus
Hepatitis
Inflammation of liver: A, B, C, D, E, F, G, H
Hernia
Protrusion of organ through wall of containing cavity
Irritable bowel syndrome
Spastic colon.
Provoked by stress, gaseous food.
Characterize by bloating, constipation, diarrhea, cramping and abdominal pain
Ulcers
Lesions located in mucous membrane lining of organ
Construction by adhesion
Abnormal growing together of two surface normally separated
Flatus
Gas, expelled by anus
Gavage
Process of feeding by nasogastric tube
Ascites
Abnormal collection of fluid in peritoneal cavity
Intussusception
One part of small intestine slide into or over an adjacent part.
Sometimes found in infants or young children, rare
Vitamin K
Necessary for synthesis of prothrombin, and several other clotting factors
-large intestine produce vitamin K
Volvulus
Twist or kink of intestine
An
Anus
Cec
Cecum
Cheil
Lip
Chol
Gall, bile
Cholangi
Bile duct
Enter
Intestine, usually small intestine
Gastr
Stomach
Gingiv
Gum
Glass, lingu
Tongue
Hepat
Liver
Lapar
Abdomen
Celi
Abdominal cavity
Sial
Saliva
Stomat, or
Mouth
Skin
-largest organ, covers all body
Epidermis
Outermost skin surface, made up of single cell layer (strata)
- contains melanin
- prevents water loss by keratin
Melanin
Pigment gives skin its color. Produced by melanocytes
Dermis
-True skin
-middle layer contains:
—blood vessels, nerves, nerve endings, glands
Subcutaneous layer
-Innermost, fatty layer
-contains:
—adipose tissue and elastic fibers that adhere to dermis to muscle surfaces
—provides body with fuel, retain heat, cushion for inner tissues
Glands
-dermis layer contains them
Sweat glands
Produce and secrete sweat assist body temp regulation, rid of body waste
Sebaceous glands
Located near hair follicles, secrete oily sebum to lubricate skin and hair
Ceruminous glands
Found in ear, secrete cerumen (earwax)
Hair
- Mostly composed of keratin tissue
- found on most body surface
- center of hair shaft called medulla
Nails
-composed of hardened keratin (horny layer), located on tip of fingers and toes
Diascopy
Examine skin lesion, use flat glass plate held against skin
Lund-browner chart
Method to estimate percentage of body that has been burned, more accurate that rule of 9. Takes age and body proportion into consideration
Rule of 9
Quick method to estimate percentage of body has been burned. Not accurate in children
Surgical excision and biopsy
Performed for lesions, moles, and tissue for pathologic study
Sweat chloride test
Procedure detect cystic fibrosis by measuring salt content of sweat
Wood’s light
Florescent light used to diagnose particular skin conditions
Acne
Inflammation of sebaceous glands
Albinism
Genetic condition marked by absence of melanin in skin, hair and eyes
Alopecia
Absence or loss of hair to entire body or body area
Dermatitis
Inflammation of skin, cause itching and redness
Diaphoresis
Excessive sweating
Eczema
Continuous or returning form of dermatitis, abnormal reaction of body immune system
-cause itching, redness, cracking, oozing, blistering, or bleeding
Furuncle
Boil
Herpes
Painful, blister like sores cause by virus
- inadequate rest, poor nutrition, stress may increase outbreaks
- simplex 1: cold sore, fever blisters on lip, mouth, face. Very contagious, spread by saliva
- simplex 2: varis cause genital herpes, sexuall transmitted
Herpes zoster
Acute viral infection, singles
- caused by dormant varicella virus reactivated later in life
- painful skin eruptions follow route of inflamed nerves
Impetigo
Very contagious bacterial skin infection due to streptococcus or straphylococcus
Keloid
Benign growth occur in scar, result of skin injury
- excessive scar tissue made of collagen and fibrous tissue
- scar is raised and often disfiguring
Macule
- freckles
- Flat skin lesion, white/brown/red
Nevus
Raised, congenital spot on skin surface
-mole
Papule
Pimple
Pediculosis
Infestation of lice, usually on head
Scabies
Itchy skin, cause by mite burring under skin
Scleroderma
Condition cause skin to thicken and become rigid
Tinea
Fungal skin infection
- ringworm
- grow on skin, hair and nails
Tinea capitis
Found of scalp of children
Tinea cruris
Found on genital area
-jock itch
Tinea pedis
Between toes
-athlete’s foot
Urticaria
Hives
-raised wheals due to allergic reaction or stress
Vesicle
Fluid filled, blister like sac on skin
Cutane, derm, dermat
Skin
Hidr
Sweat
Kerat
Horny tissue, hard
Onych , ungu
Nail
Trich
Hair
Crypt
Hidden
Heter
Other
Myc
Fungus
Pachy
Thick
Rhytid
Wrinkles
Xer
Dry
Nose
- Lined with cilia and hair to clean air
- warms, cleans, moisturizes air
Sinuses
- Air space in bones of face
- lined with ciliated mucous membranes
- warms, cleans, moisturizes air
Mouth
- Takes in extra air when needed: during exercise or nasal passage blockage
- does not have any moisturizing capacity
- inhaled air takes available moisture, drying mouth
Pharynx
Throat
-serve as passageway for air and food from mouth go hyoid bone
Epiglottis
- consist of cartilage flap
- function as valve, covers larynx as swallow
Larynx
-contains glottis and vocal cords, located right below epiglottis
-consist of cartilage and muscle
-back up for epiglottis
—epiglottis moves to cover larynx, muscle of larynx squeeze shut
Trachea
Windpipe
- positioned anterior to esophagus within neck
- smooth muscle reinforced with rings of cartilage
- rings are c shaped with open end next to esophagus
- rings prevent trachea from collapsing
Bronchi
- two primary bronchi splits off from trachea, 1 to each lung
- bronchioles split off as smaller branches from bronchi
Alveoli
Air sacs at bronchiole ends
-1 cell thick
-exchange of gases occur
—oxygen enters surrounding blood capillaries
—carbon dioxide enters alveoli from surround blood capillaries
—-process known as external respiration
Lungs
Main respiratory organ
- in thoracic cavity, protected by bone (sternum, ribs, vertebrae) and by intercostal and diaphragm muscle
- left lung has 2 lobes
- right has 3 lobes
Pleura
Serous membrane lining lungs has surfactant to lower surface tensions
Thorax
Cavity contains the lung
Diaphragm
- Domed muscle separates thoracic and abdominal cavity
- on inhalation: it contracts, create room for inflation of lungs
- on exhalation: relaxes, assist lung compression
Cilia
Tiny hair like projections located on surface of lining of trachea, bronchi, inside nostrils
-filter incoming air to move mucus or particles out of respiratory tract
Expirations reserve volume
Extra air forcible exhaled after normal exhalation
External respiration
Exchange of oxygen and carbon dioxide in lungs and blood capillaries
Functional residual volume
Amount of air left in lungs after normal expiration
Inspiration captivity
Inspiration reserve volume
- maximum amount of air inspired after normal expiration
- measured by breathing in and out normally, then forcibly inhaling at end of tidal volume
Internal respiration
Exchange of oxygen and carbon monoxide between capillaries and tissue cells
Rales
Increased secretion in bronchi causing crackling breath sounds
Residual volume
Volume of air left in lungs after forced expiration
Tidal volume
Volume of air inspired and expired during a normal respiration
Total lung capacity
Total volume of air can be in lung at one time
Vital capacity
Maximum amount of air expired after maximum inspiration
-not forced
Wheeze
Squeaking, whistling breath sound cause by narrowing tracheobronchial airways
-occurs in asthma, bronchitis, other respiratory disorder
Bronchoscopy
Procedure provides an interior view of bronchial air passage
Chest X-ray
Radiological picture of lungs
Pulmonary function test
Group of test is used to measure various lung capacities
-amount and rate of air taken in and released
Acute respiratory distress syndrome
Acute respiratory failure
Sudden onset of lung dysfunction making breathing extremely difficult especially
-affects both lungs caused by trauma, sepsis, pneumonia or shock
Asthma
Affects bronchi and bronchioles
- airways become partially blocked by contraction of muscle walls
- narrowed airways cause by wheezing, chest tightness, severe dyspnea
- usually related to allergies, exercise or environmental agents
Atelectasis
Incomplete lung expansion
- absence of air in lungs and alveoli cause structure to collapse
- may be caused by cancer, asthma, or pneumonia
- sx: dyspnea and hypoxia
Bronchitis
Inflammation of bronchi
Acute bronchitis
Common complication of ordinary colds, usually secondary bacterial infection
-sx: fever, dyspnea, sneezing, yellow-green sputum and productive cough
Chronic bronchitis
Chronic obstructive pulmonary disease
- leads to lung damage, eventual respiratory failure and death
- sx: similar to acute bronchitis, but occur over long period and several times a year
Chronic obstructive pulmonary disease
Combo of asthma, chronic bronchitis and emphysema
- cause enlargement of lung alveoli
- condition progressive and obstructs air exchange in bronchi, alveoli and lungs
Croup
Acute virus affecting larynx, trachea, and bronchi with inflammation and spasm
- disease of early childhood and infants
- pronounced barking cough and hoarseness
Cystic fibrosis
Abnormally thick mucus secretion clogging lungs and pancreas, result in impaired breathing
-cause is genetic
Emphysema
Form of COPD, which enlargement and loss of alveoli and decrease elasticity of lungs lead to progressive loss of function
- cause by smoking, previous history of smoking
- sx: increase difficult, rapid, shallow breathing
Pertussis
Whooping cough
- contagious bacterial infection cause inflammation in upper respiratory system
- may be fatal to infants
- vaccine is available
Pleurisy
Inflammation of pleura cause sharp pain with each breath taken
-cause maybe injury beneath pleura or influenza
Pneumonia
Infection and inflammation of lung tissue
- pus and other liquid present in alveoli and bronchioles make it difficult for air to reach alveoli
- cause may be bacteria, fungi, virus, inhaled agents
- named causative agent
Pulmonary edema
Fluid accumulates in lungs from blood capillaries around alveoli, result from malfunction of heart
- associated with CHF
- sx: progressive dyspnea, nonproductive cough and cyanosis
Tuberculosis
Infection with mycobacterium tuberculosis cause nodule in lungs, damage to lung tissues, scarring and dyspnea
- will progress if not treated and be fatal
- sx: slight fever, fatigue, weight loss, unproductive cough, bloody pus filled phlegm
Lob
Lobe
Nas, rhin
Nose
Pneum, pneumat, pneumon
Lung, air
Pulmo
Lung
Muc
Mucus
Ox
Oxygen
Py
Pus
Spir
Breathe, breathing
Neurons
Nerve cell carry nerve impulse to and from and within CNS
-working cells of nervous system
Cell body
Holds nucleus of cell and other regular cell parts
- does not have centriole, cannot reproduce
- protected in brain, spinal cord and ganglion
Dendrites
Extension of cell, receives and carries signal to cell body
Axon
Cell part carries impulses from cell body to other neurons or body tissues
Myelin sheath
Lipid and protein -covers the axon of PNS cell -white matter on nerve cells -made of Schwann cells -gaps called nodes of Ranvier -CNS neurons do not have them, cannot be repaired —they are grey matter cells
Synapse
Gap between neurons and muscle tissue is designed so impulses can travel in a single unmyelinated fibers
-released neurotransmitter chemical assist or inhibits impulse transmission to cross the synapse to another cell
Peripheral nervous system
- consist of nerves and ganglia located outside CNS
- nerve consist of many neurons bundled together with blood vessels, wrap in connective tissue
Sensory neurons
Transmit impulses from rest of body to CNS
Motor neurons
Transmit impulses from CNS to muscle and glands
Interneurons
CNS neurons bridge between sensory and motor neurons
Somatic system
Sends behavior information to and from CNS to skeletal muscle
- afferent nerve: bring sensory information from different parts of body to CNS
- efferent nerves: bring motor information from CNS to skeletal muscles
Autonomic nervous system
Sends behaviors information from CNS to smooth muscles, cardiac muscles and glands
Sympathetic nervous system
Responsible for automatic reaction to stress
-fight or flight response
—heart rate increase, strength increase, bronchial tube dilate
Parasympathetic nervous system
Responsible for conservation/restoration of energy and elimination of waste
—heart rate decrease, bronchial tube constrict
Olfactory
I
Sense of smell
Optic
II
Vision
Oculomotor
III
Movement of eyeball, eyelids, regulate pupil size
Trochlear
IV
Movement of eyeball
Trigeminal
V
Sensation in head and face, chewing
Abducens
VI
Eyeball movement
Facial
VII
Taste, facial expression, secretion of tears and saliva
Acoustic
VIII
Hearing and balance
Glossopharyngeal
IX
Taste, swallowing, secretion of saliva
Vagus
X
Sensation in larynx, trachea, heart, stomach and other organs. Organ movements
Spinal accessory
XI
Movement of shoulders and head
Hypoglossal
XII
Tongue movement
Spinal nerve
31 pairs of spinal nerves
-extend from spinal cord, named for originating vertebrae
Cervical plexus
C1-C5
Nerve supply skin and muscles of neck
-major nerve emerging from plexus: phrenic nerve (controls diaphragm)
Brachial plexus
C5-C8, T1
Supply skin and muscle of shoulder, arms, forearm, wrist and hand
Lumbosacral plexus
T12, L1-L5, S1 to end
Supply skin and muscle of external genitalia, buttocks, lower ab wall, lower extremities
-major nerve emerging: sciatic nerve
Brain
Encephalon
- weigh 3 lbs
- divide into 4 major areas: cerebrum, diencephalon, brain stem, cerebellum
- protected by skull, meninges, cerebrospinal fluid
Cerebrum
-left and right hemispheres
-control center for sensory, motor and intellectual functions
-covered with cerebral cortex of gray matter 2-4 mm thick arrange in folds
-bulk composed of white matter
-contain 10-14 billions neurons and synapses
-2 halves not completely separate
—fissure between is bridged in center by band of white fibers: corpus callosum , serve as communication between sides
-left hemisphere for logic, complex mathematic, and language
-right hemisphere for creativity, music and art appreciation
-each hemisphere has 4 lobes: frontal, parietal, occipital and temporal
Frontal
Controls speech and voluntary muscle movement
Parietal
Process sensory information from skin and control depth perception, size, and shape
Temporal
Controls interpretation of sound and smell, personality, behavior, emotion and memory
Occipital
Interpret visual information
Diencephalon
- compose of gray matter
- contains thalamus, hypothalamus, pineal gland
- link between decision are made and body, which carries out those division
Cerebellum
- located below cerebral hemisphere, attached to posterior brain stem
- little brain
- maintain muscle tone, balance, posture and fine motor movements
Brain stem
Hindbrain
-consist of 3 parts: medulla oblongata, pons, midbrain
Medulla oblongata
Lowest part, channel communication between spinal cord and brain
Pons
Help regulate breathing
Midbrain
Nerve tissue connects the pons to lower part of cerebrum
-vision and hearing reflexes located here
Spinal cord
- made up of gray and white matter
- serves as pathway for impulses to travel to and from brain
- begins at medulla oblongata and extends to 2nd lumbar vertebra
- protected by skull and vertebrae
- enclosed in meninges: dura mater, arachnoid and pia mater
Dura mater
Meninges
Outermost layer
Arachnoid
Meninges, lacy spiderweb
Pia mater
Innermost layer of meninges
CSF
Made in ventricle of brain by masses of capillaries
- fluid in subarachnoid space: between arachnoid and pia mater
- is clear, colorless and watery
- functions to make meninges into fluid-filled cushion
Blood brain barrier
Mechanics of capillary walls of brain regulates materials in bloodstream are permitted to enter brain
-chemical excesses or deficiencies cause arteries to dilate or constricted until a balance is restored
Hypothalamus
- just below thalamus
- regulates emotional responses, body temp, hunger sensation, thirst sensation, sleep-wakefulness cycle, pituitary and endocrine system actions, autonomic nervous system: heart rate, by, respiratory rate and digestive action
Pineal gland
Part of endocrine system
-produce and secrete melatonin
-inactive during day, activates when darkness occurs
—control sleep-wake cycle
Plexuses
Networks
-spinal nerve fibers converge to form networks in PNS
Thalamus
- below cerebrum
- process impulse relayed to and from cerebrum and sense organ
Cerebral angiography
Imaging procedure use a contras medium to view blood vessels of brain
Computed tomography scan
Image procedure use series of X-ray to create cross-sectional 3D picture
Electroencephalogram
Test measure electrical activity of brain
Lumbar puncture
Extracts CSF below L3-L4 obtain RBC and WBC counts
Magnetic resonance imaging
Use magnetic field and radio waves, gives pictures of brain soft tissue
Myelogram
Uses radiopaque medium and X-ray to view interior of spinal cord
Patellar, babinski, Achilles, corneal reflex test
Test performed to evaluate motor neurons functions
X-ray
Skull and spine
-radiograph imaging used to diagnose injuries, tumors, spondylitis of vertebrae
Alzheimer’s disease
Frontal and temporal look nerve cells die, degenerative, dementia like disease impairs physical abilities, lessens intellect, result in gradual total memory loss
Bell palsy
Infection cause 1 sided facial paralysis
Affect cranial nerve VII
Caused by herpes simplex reactivation, most often resolves in 2 weeks to 2 months
Carpal tunnel syndrome
Pressure on wrist median nerve cause pain, numbness
-cause by repetitive motion over time
Cerebral palsy
Brain damage occur in utero or birth, cause mental retardation, seizure, spastic moves
CVA
Stroke
- sudden loss of neurological function cause by brain circulation block or vessel rupture
- loss of function depends on location of brain damage
Epilepsy
Condition of periodic seizures cause by malfunction of electrical activity of brain
Hydrocephalus
Excess CSF in brain cause elevated intracranial pressure and tissue death
Meningitis
Viral or bacteria infection of meninges covering of brain
Multiple sclerosis
Progressive, debilitating disease cause by gaps in white matter myelin sheath
-produce increasing weakness, tremors, and vision problems
Parkinson’s disease
Debilitating disease cause by abnormal low supply of dopamine
-increase in body tremors, involuntary movement and loss of balance
Sciatica
Inflammation of sciatic nerve
- sx: sharp pain alone nerve and branches
- pain regulates from butt to hip and thigh area
TIA
Sudden loss of specific neurological function, full recovery expected 24 hours
- serve as a warning of possible upcoming stroke
- cause by embolus to brain, that is resolved by body circulatory system
Seizure
Sudden surge of electrical brain activity commonly referred to electrical storm
-has effect on behavior, and overall feeling for short time
Petit mal
Seizure occurs in childhood
-has mental shutdown for 30 seconds
Grand mal
- occur at any age
- falls down unconscious, goes rigid, twitches or jerks rhythmically, slowly regains consciousness
- followed by deep sleep or confusion
- may be preceded as aura or warning
Focal seizure
Begin with uncontrollable twitching in single part of body, spreads surrounding structures and eventually full body
-patient conscious
Temporal lobe seizure
After brief aura, patient suddenly acts out of character for few minutes
-unconscious chewing motion may occur
Cerebell
Cerebellum
Cerebr
Cerebrum
Dur
Hard
Encephal
Brain
Radic, radicul, rhiz
Nerve root
Esthesi
Sensation, sensitivity, feeling
Phas
Speech
Poli
Gray matter
Psych, ment, phren
Mind
Anterior pituitary
- growth hormone
- prolactin
- thyroid-stimulating hormone
- adrenocorticotropic hormone
- follicle stimulating hormone
- luteinizing hormone
Growth hormone
Anterior pituitary
- target: bone, muscle, soft tissue
- function: stimulate tissue growth, decrease glucose
Prolactin
anterior pituitary gland
Target: mammary gland (breast)
Function: initiate milk production, promote milk gland production
Thyroid-stimulating hormone
Anterior pituitary gland
- target: thyroid gland
- function: growth, development, thyroid activity as metabolism regulator
Adrenocorticotropic hormone
Anterior pituitary
Target: adrenal gland (cortex)
Function: maintenance of gland, stimulate secretion of cortisol
Follicle stimulating hormoner
Anterior pituitary
- target: overian follicles, seminiferous tubule in testes
- function: women: stimulate development of ova and ovulation. Men: stimulate development and function of testes, production of sperm
Luteinizing hormone
Anterior pituitary gland
- target: overlies, testes—cell of Leydig
- function: development of corpus luteinizing, progesterone secretion, developer cell to make testosterone, stimulate secretion of testosterone
Posterior pituitary
- Antidiuretic hormone
- oxytocin
Antidiuretic hormone
Posterior pituitary
ADH, vasopressin
-target: kidney
-function: regulates water reabsorption within nephrons, determine urine concentration and volume
Oxytocin
Posterior pituitary
- target: uterus, breast
- function: stimulates birth contractions and cause milk ejection
Thyroid gland
- Thyroxine (t4)
- triiodothyronine (t3)
- calcitonin
Thyroxine
T4
Thyroid gland
-target: tissue cells
-function: increases metabolic rate
Triiodothyronine
Thyroid gland
T3
-target: tissue cells
-function: increase metabolic rate
Calcitonin
Thyroid gland
- target: bone
- function: inhibits bone loss, lower blood calcium concentration
Parathyroid gland
-parathyroid hormone
Parathyroid hormone
Parathyroid gland
Parathormone
-target: intestine, bones
-function: increase absorption of calcium into bloodstream, raises excretion of phosphates in urine
Adrenal cortex (outer)
- cortisol
- aldosterone
- androgens
Cortisol
Adrenal cortex gland
ACTH
-target: all cell except liver cells
-function: increase breakdown of protein into amino acids, breakdown of fat, assist in stress, raise blood glucose
Aldosterone
- adrenal cortex gland
- target: kidney
- function: regulate blood pH, stimulates reabsorption of sodium in nephrons
Androgens
Andrenal cortex
- target: gonads
- function: stimulates development of secondary sex characteristics (especially females)
Adrenal medulla
- epinephrine
- norepinephrine
Epinephrine
Adrenal medulla
- adrenaline
- target: smooth and cardiac muscle, blood vessels, liver cells
- function: raise heart rate, blood pressure, blood glucose levels
Norepinephrine
Adrenal medulla
- target: smooth, cardiac, striated muscles
- function: constrict blood vessels, raise blood pressure, reinforces sympathetic nervous system
Pancreas gland
- Glucagon
- insulin
Glucagon
Pancreas gland
- target: liver cells, fat cells
- function: promotes release of glucose into blood
Insulin
Pancreas gland
- target: all cells except brain
- function: promote use and storage of glucose in cells
Melatonin
Pineal gland
- target: pituitary, gonads
- function: regulate sexual development, timing of puberty
Thymosin
Thymus gland
- target: immune system
- function: stimulates T-cells production
Testosterone
Teste
- target: sperm cells
- function: stimulates sperm production, secondary sex characteristics
Estrogen
Ovaries
- target: breast, uterus
- function: stimulate breast growth, uterus, secondary sex characteristics
Progesterone
Ovaries
- target: uterine lining
- function: prepare uterus for pregnancy
Hypothalamus
- Regulates pituitary gland
- secretion control hormones secreted by pituitary
Metabolism
Sum total of all chemical processes take place in living organism
Pituitary gland
Referred to as master gland
Steroid
Hormone-like substance either pharmaceuticals produced or secreted by endocrine to relief inflammation due to allergic reaction, asthma, other condition
Anabolic steroids
- Male testosterone related
- used to increase muscle mass and strength
- mental side effects: violence, mood swings
- physical side effects: breast development in men, testicular shrinkage, changes in body chemistry, liver damage
Syndrome
Set of symptoms run occur together
Bone density xray
Radiographic image of hip bone
-measure degree of calcium loss`
CT scan
Cross-sectional radiographic scan
-cause of gland enlargement or loss of hormone production
Fasting plasma glucose test
Procedure determine patient normal blood glucose level
Glucose tolerance test
Timed test find effective rate of glucose absorption into cells
-performed during pregnancy check for gestational diabetes
Thyroid scan
Done by administering pharmaceutical radioactive iodine
- rates thyroid activity for metabolic regulation
- information about size, shape, location of any abnormalities
24 hour urine collection
Test for concentration, level of glucose, calcium, steroid, vitamin K and other substance
Acidosis
Abnormal accumulation of acid products of metabolism
-uncontrolled diabetes mellitus
Acromegaly
Abnormally high level of growth hormone in adults
-due to pituitary gland tumor
Addison disease
Caused by slowly destroyed adrenal cortex, lowering of adrenocorticotropic hormone
-result in weight loss, nausea, abdominal pain, bronzed skin, hypotension
Cretinism
Congenital condition of hypothyroidism in infants and children
-result in abnormally developed brain
Cushing syndrome
Caused by long-term exposure high levels of ACTH or adrenal gland tumor
-moon face, thin limbs, obese torso
Diabetes insipidus
Low level of antidiuretic hormone
-result in polydipsia, polyurethaning, dehydration, dry skin
Diabetes mellitus
Metabolic disorder
-deficient insulin production in pancreas, increased cell resistance to insulin
Type I diabetes
- Little or no insulin production
- insulin dependent diabetes mellitus
- onset before age 30 years
- hereditary, result form viral infection
Type 2 diabetes
- Insulin resistant
- non-insulin dependent diabetes mellitus
- adult onset
- result from obesity, pregnancy
- most common type
Goiter
Swollen neck due to enlarge thyroid
-result in iodine deficiency, condition cause under active or overactive thyroid
Graves’ disease
Form of hyperthyroidism (thyrotoxicosis)
- caused by destruction of thyroid gland
- evidence of high metabolic rate, exophthalmia and anxiety
Hashimoto disease
Chronic lymphocytic thyroiditis
- thyroid cells destroyed by body owns antibodies
- autoimmune
- condition of hypothyroidism
Hyperthyroidism
Overproduction, secretion of thyroid hormones increase metabolic rate
-result in weight loss, sweating, nervousness
Hypothyroidism
Under active thyroid
- cause deficiency in hormone secretion
- result in decrease metabolic rate, fatigue, depression, cold sensitivity
Myxedema
Severe type of hypothyroidism
- more common in women over 50
- cause obesity, thyroid removal, radiation to neck area
- sx: fatigue, abnormal low temp, hair loss, swelling: face, hands, feet
Parathyroid tetany
Muscle spasm, convulsion
- result from hypoparathyroidism
- disorder result low calcium levels in body
Seasonal affective disorder
Depressive mood disorder during winter months
-possible linked to increase melatonin production
Acr
Extremities, height
Calc
Calcium
Dips
Thirst
Kal
Potassium
Toxic
Poison
Blood circulation in kidney
- enters kidney by renal artery
- waste products are removed as circulates in nephrons within kidney
- per minute: heart pumps 1/5 (1200 mL) of body blood supply to kidney
Kidney
- located between 12T and 3L vertebrae, behind abdominal cavity
- secrete erythropoietin: acts to stimulate production of RBC
- bean shape
- center of kidney concave side: hilus, renal artery enter here, ureter and renal vein exit here
Hilus
Concave side of kidney
-renal artery enters here, ureter and renal vein exits here
Cortex
Outer portion of kidney
Medulla
Inner portion of kidney
- contain 12 renal pyramid
- each pyramid connects with calyx (duct), joins renal pelvis (urine reservoir)
Ureter
Collects produced urine, delivers to bladder
Nephrons
Kidney function units
- 3 functions: filtration, reabsorption and secretion
- about 1.25 millions per kidney
- each surrounded by blood capillaries
Glomerulus
Blood enters nephron here
Bowman’s capsule
Blood filtration takes place here
Proximal tubule
Reabsorption begins
-concentration or chemical content of urine is determine
Loop of Henle
Urine formation continues
Distal tubule
Last area of urine formation
Collecting duct
- Urine formation is completed
- urine passes to pyramids
- glucose and amino acids are reabsorbed into blood from nephron tubules: if excess in blood, renal threshold occurs, become part of urine content
Ureters
Slender tube extend from kidney hilus to lower surface of bladder
-urine propelled through ureters by peristalsis, flow through mucous flap into bladder
Bladder
- Hollow organ, reservoir of urine
- has mucus membrane lining of rugae cells: allow to stretch
- empty bladder is size of walnut
- 150-250 mL stimulate mictuiration (void of urine)
- urine exits bladder: internal sphincter, located urethra connects to bladder
Urethra
- Convey urine out of body
- 4 cm long in woman, 20 cm long in men
- in women: leads directly from bladder to urinary meatus
- in males: urethra passes through prostate before exiting urinary meatus
- has external sphincter (voluntary) signal urge to void
Renal threshold
Occurrence of certain substance found in urine, as a result of excessive amount found in blood
-normally reabsorbed into blood from nephron tubules
Urochrome
Pigment give urine its color
-ranges from straw to amber yellow depend on liquid consumed, disease and medication
Dialysis
Artificial filtration of waste material from circulating blood
Intravenous pyelogram
Xray use dye to evaluate structure and function of kidney
Routine urinalysis
Lab analysis of urine checks physical properties, specific gravity, basic chemistry
Urine culture
Identify any pathogen causing problem
- clean catch midstream specimen required
- incubated for 24 hours, bacteria developed identified and counted
- antibiotic are tested
Urinary catheterization
Removes or introduce fluid by inserting sterile tube through urethra, into bladder
Cystitis
Bladder inflammation due to bacterial infection
-e. Coli
Glomerulonephritis
Inflammation of glomeruli within kidney nephrons affect filtration and reabsorption
- loses ability to be selectively permeable
- occur as complication of streptococcal infection, renal disease, immune disorder or bacterial infection
- sx: drowsiness, coma, seizure, nausea, anemia, high blood
Hyperkalemia
Electrolyte balance disorder
-cause by high potassium levels
Polycystic kidney disease
Multiple cyst produced in kidney tubules
-lead to kidney failure
Pyelonephritis
Bacterial infection affect renal pelvis
- acute form: due to bladder infection move up ureters to kidney
- chronic form: repeated undetected urinary tract infection, periodically affect kidney
- kidney become less efficient, waste product accumulate in body
- kidney or bladder stone can be source of infection
- sx: fatigue, frequent urination, itchy skin, nausea
Renal calculi
Kidney stones of calcium, may block urinary flow
-more common in men
Renal failure
Gradual loss of renal function cause by repeated infection or other disease
-acute or chronic
Urinary incontinence
Inability to maintain control of urination
Wilma tumor
Forms outside of kidney and metastasize in blood stream, to liver, sometimes to brain.
- usually occur in children less than 5 years
- highest survival rate of all childhood cancer
- sx: weight loss, anorexia, vomiting, blood in urine
Azot
Urea, nitrogen
Cyst, vesic
Bladder, sac
Hydr
Water
Lith
Stone, calculus
Meat
Meatus
Nephr, ren
Kidney
Noct
Night
Olig
Scant, few
Pyel
Renal pelvis
Ovaries
2 glands manufacture ova and secrete estrogen, progesterone
Fallopian tube
- Tube curl around top of each ovary, connect top corners of uterus transport ova to uterus
- fertilization by sperm occur here
Uterus
- Hallow, muscular organ
- contains and nourishes developing embryo and fetus
- top called fundus
- upper 2/3 uterus
- lower 1/3 cervix
- inner wall: endometrium
Vagina
- Muscular tube leads from uterus to outside of body
- inner layer: rugae cell for expansion
- surround partially covered by thin membrane: hymen
- function: lower end of birth canal, receive male organ and sperm
- passageway to outside for menstrual flow
Vulva
External genitals
Mons pubis
Fatty tissue over pubic bone
Labia majora
Vulval lips
- 2 fold of gskin tissue, enclose and protect uethral and vaginal opening
- have hair on outside
Clitoris
Erectile tissue, covered by prepuce
Skene and bartholin glands
Urethral, vaginal glands
Secrete mucus and lubricating fluid
Breast
Mammary glands produce milk
Scrotum and testes
Testes suspended in sac of loose skin (scrotum)
- before birth testes move from ab cavity to scrotum
- testes make sperm
Epididymis
Tightly coiled tube, attached to side of each testis
- sperm mature and store here
- one end connects to testes, other end leads into vas deferens
Vas deferens
Tube move the sperm from epididymis to seminal vesicle
Seminal vesicles
Gland secrete fructose-rich fluid
-fluid mix with sperm passing through vas deferens
Ejaculatory duct
Merging vas deferens and seminal vesicles
-duct pass through middle of prostate, joins the urethra
Prostate gland
Donut like shape encircles ejaculatory duct
- secrete thin alkaline fluid added to semen, makes up 60%
- fluid protect sperm from acid as passes through urethra
Cowper or bulbourethral gland
Gland secrete alkaline fluid makes up 5% of semen
Urethra and penis
Urethra: 20 cm tube, extends from ejaculatory duct to tip of penis
Penis: organ for copulation and urination
-contains erectile tissue, become engorged with blood, stiffens when stimulated
-erection enable entry to female vagina
-penis glans is penis tip, slightly wider than rest
-prepuce (foreskin) extend over glan
Apgar scoring system
Initial test assess health of newborn
-five signs are checked and scored: heart rate, respiratory rate, muscle tone, reflex irritability and color
Braxton-hicks contraction
Uncoordinated and irregular contractions
-occur frequently last month, sometimes earlier before labor
Chadwick sign
Thickening of vagina, development of purplish color (vagina and cervix)
Embryo
Fertilized egg through 8 weeks of development
Fimbriae
Finger like projection on Fallopian tube, produce pulling action on ovum to draw into tubes after rupturing from ovary
Gestation
Period of pregnancy from fertilization to birth
Goodell sigh
Softening of cervix 5-6 weeks after fertilization
Menarche
Initial onset of female menses
-age 9-15 years old
Menopause
Cessation of menstruation
-48-50 years old
Menstruation
Menses
- shedding of endometrial lining due to non pregnancy
- approx every 28 days
Mitosis
Process describing 1 cell begin to multiply through division
Naegele rule
Formula calculate estimated date of confinement, estimated date of delivery
Perineum
Area of macule locate between anus and external genitals
-provide support for internal organs
Parturition
Process of labor and delivery
Placenta
Spongy structure on uterine wall during pregnancy, joined to fetus by umbilical cord
- exchange waste, nutrients and oxygen
- temp endocrine gland, secrete human chorionic gonadotrophin early in pregnancy
Quickening
Women initial awareness of movement of fetus
-occur between 18-20 weeks of pregnancy
Teratogen
Potent
- toxic substance able to cross placental membrane and harm embryo
- monster producing
Zygote
Fertilized egg cell produced when sperm head unites with nucleus of ovum
Amniocentesis
Needle insert into amniotic sac to remove fluid for analysis
Cesarean section
Surgical removal of fetus
-during delivery process difficult and hazardous, pose high risk for mother and fetus
Colposcopy
Visual exam by colposcope of vagina wall and cervix for abnormal cells
Dilation and curettage
Dilates cervix, scrape wall of uterus to remove tissue
Episiotomy
Clean surgical cut perineum done during labor
- muscle great deal of stress during delivery
- to prevent irregular or deep tearing
Hysterectomy
Removal of uterus,
-Fallopian tube, ovaries may be removed same time
Mammogram
Xray of breast
Tubal ligation
Sterilization accomplish by severing, knotting or blocking Fallopian tubes
Pap smear
Papanicolaou test
-takes cell scraping of cervix and vagina test for abnormal cell growth
Circumcision
Surgical removal of foreskin of penis
Prostate specific antigen test
Measure blood level of PSA protein release by prostate
-to indicate prostate cancer
Vasectomy
Removal or knotting of vas deferens for sterilization
Cystocele
Outpouching of bladder, protrudes into vagina, may cause urinary urgency
Eclampsia
Toxemia of pregnancy
Condition cause elevated BP, edema, protein in urine
-if left untreated, cause death
Ectopic pregnancy
Require surgery, fetus implanted outside uterus
Endometriosis
Presence of endometrial tissue outside uterus
Cause pain, cysts, tumors
Pelvic inflammatory disease
Widespread bacterial infection of reproductive organs
Placenta previa
Placenta attach to lower uterine wall, partially or fully block birth canal
Premenstrual syndrome
Characterized by symptoms of anxiety, bloating, irritability, headache and depression
Down syndrome
-mild or severe mental retardation of individual born with extra chromosome (number 21)
Fetal alcohol syndrome
Birth defect
-facial deformities, mental and neurologic developed damage cause by alcohol consumption during embryonic period of pregnancy
Phenylketonuria
Excess accumulation of phenylalanine occur when defective enzyme cannot metabolize substance
-can cause brain damage
Sudden infant death syndrome
Occur when autonomic respiratory system stops
Spina bifida
Birth defect expose spinal column, usually lumbar region
Benign prostatic hypertrophy
Enlargement of prostate, common in men over 50
Cryptorchidism
Failure of testes to descend into scrotum before birth
Epididymitis
Inflammation of epididymis, cause pain during urination, pain and swelling of scrotum
Hydrocele
Accumulation of fluid within teste
AIDS
Advance stage of infection of HIV virus
- decrease in immunity
- cure does not exist
Chlamydia
Genitourinary infection cause by chlamydia trachomatis
- most common sexual transmitted disease
- can cause women to develop PID
Condyloma
Wart growth locate on external genitalia, cause cervical cancer
Gonorrhea
Genital mucous membrane inflammation produce from exposure to neisseria gonorrhoeae
Herpes genitalis
Viral infection
- painful fluid filled vesicles on genitals
- can cause female cervical cancer
Syphilis
Multistage genitourinary infection by treponema pallidum
-1st stage: lesion (chancres) any organ and body part
Trichomoniasis
Genitourinary parasitic infection (trichomonas vaginalis), can result in vaginitis
Arche
1st, beginning
Colp, vagin
Vagina
Culd
Cul-de-sac
Episi, vulv
Vulva
Gynec, gyn
Woman
Hyster, metr, uter
Uterus
Mamm, mast
Breast
Men
Menstruation
Oophor
Ovary
Salping
Fallopian tubes
Andr
Male
Balan
Glans penis
Epididym
Epididymis
Orchid, orch, test
Testis
Vas
Vessel, duct
gustatory component
receptors for taste: on tongue and soft palate.
papillae: raised area on tongue detects 4 taste- sweet, salt, sour and bitter
olfactory components
smell receptors used in tasting, odor detection located in mucous lining of upper part of nose
vision components
- receptors for vision in retina
- eyelids, eyelashes, eyebrows and tears: protective structors clean and moisturize eye
- lacrimal gland: secrete tears and located outside upper edge of each eye
sclera
outer layer of eye
-white of the eye
cornea
outer layer of eye, windows
-transparent structure in front of eye help focus light to enter
iris
second layer of eye
- pigmented layer of muscles behind cornea
- in front of lens enables more or less light to enter in opening in center: known as pupil
retina
third layer of eye
- lines interior of eyeball
- made up of rods: detect gray tones
- cones: light and color
- greater concentration at back of eye interior
lens
interior of eye
- located behind cornea and iris
- enables eye to focus: process called accommodation
vitreous humor
interior of eye
- jelly-like substance fills chamber behind lens
- function: maintain shape of eye and support retina
outer ear
external auditory canal extends from pinna outward, inward, forward, downward into interior of skull to eardrum
pinna
auricle
-skin and cartilage make shape of outer ear
eardrum
auditory membrane vibrates as sound waves hit it
middle ear
tympanic cavity, connected to nasopharynx by eustachian tube
malleus, incus, stapes
ossicles
- in middle ear
- bones move and pass vibration from middle to inner ear
inner ear
labyrinth
vestibules
small chamber containing receptors for balance and position sense
semicircular canals
canals also contain receptors for balance and position sense
cochlea
stapes communicate with cochlea
- spiral shaped
- contains fluid sac and tubes, has neural cells for hearing
- sound waves start fluid moving within here, so hairs bend to carry nerve impulse to acoustic nerve, then to temporal lobe to interpret sound
accommodation
action of eye lens to change shape to bend light to focus it on retina
- allow eye to adjust for differences in light due to distance
- lens become convex or concave
- greater the bulge, more light enters
blind spot
optic disk
-region where optic nerve leaves eyeball, which does not contain rods and cones
eustachian tube
auditory tube
- begins in middle ear cavity within temporal bone
- area full of air
- connected to nasopharynx
- tube normally flatten and closed
- opens with yawning or swallowing
- purpose to equalize pressure on both side of tympanic membrane
audiometry
test emits measured sounds to evaluate hearing
electrocochleography
measure electrical activity in cochlea in response to sound to determine cochlea’s fluid pressure
refraction assessment
checks for necessary visual correction or glasses
tonometry
intraocular pressure test check for glaucoma
visual acuity test
known as snellen eye chart to measure distance vision, near vision, color vision using Ishihara methods for evaluation
amblyopia
lazy eye
- occurs when eye is not used
- may be result of misalignment by muscles that control eye movement
- eye gets progressively weaker, resulting in blurred vision
- eye appearing to turn inward or outward
astigmatism
uneven curvature of cornea result in vision distortion
cataract
cloudiness of eye lens result in vision degeneration, from aging
color blindness
inability to distinguish certain colors
- most common: red from green
- absense or deficiency of single type of cone
- red-green blindness more common in males
- present at birth, inherited
conjunctivitis
pink eye
- allergic reaction, bacteria or viral infection cause blood vessels to inflame
- turns eye white red/pink
- sx: itchy eye, swollen eyelids, watery or sticky discharge
exophtalmia
abnormal bulging of eye out of orbits, caused by hyperthyroidism
glaucoma
abnormally high pressure on optic nerve
-can cause blindness due to oxygen cannot reach rods and cones
hypermetropia
farsightedness
- result eye is too short from front to back
- light entering eye is focused behind the retina
iritis
inflammation of iris tissue
- cells from tissue may begin to flake off, float in aqueous humor
- -interfere with vision
- becomes red and painful
- untreated, may cause acute glaucoma
macular degeneration
progressive deterioration of macula cause loss of central vision
- occurs due to retina no longer receives adequate blood supply
- most common vision loss in US
meniere disease
increase of fluid in semicircular canal of ear
-result in sx of vertigo, nausea, progress hearing loss, tinnitus
myopia
nearsightedness
- eye globe is too long from cornea to retina
- light entering eye is focused in front of retina
night blindness
result from lack of vitamin A
otitis externa
inflammation or infection of external ear canal
- swimmers ear
- most common cause bacterial infection
otitis media
common middle ear infection in infants
- start at throat, travels up eustachian tube
- result of upper respiratory infection
otosclerosis
abnormal bone growth, immobilization of stapes leads to conductive hearing loss
- may be genetic
- more common in females
presbyopia
hardening of eye lens result in loss of lens flexibility
- from aging
- seeing object up close becomes more difficult
strabismus
crossed eyed
- poor alignment of eye muscles
- eye do not focus together
- 1 or both eyes turn inward or outward
- sx: blurred vision, poor depth perception
stye
eyelash follicle infection. Painful, red swelling develop in white center and bursts
vertigo
dizziness
blephar
eyelid
cor, core, pupil
pupil
corne, kerat
cornea
dacry, lacrim
tear, tear duct
ocul, ophthalm
eye
opt
vision
phot
light
ton
tension, pressure
acou, audi
hearing
aur, ot
ear
miring
tympanic membrane
tympan
eardrum, middle ear
Lymphocyte
WBC formed in red bone marrow
-mature within spleen, liver, and lymph node to trap and destroy microorganisms and fight against pathogens
T cells
Mature in thymus, reside in lymph tissue (spleen) and blood
-attack cell to cell contact: phagocytosis (cell-mediated immunity)
B cells
Mature in bone marrow, reside in lymph tissue (spleen) and blood
-indirectly attack by secreting antibodies (antibody-mediated immunity)
Lymph nodes
Pea-shaped cluster of lymph tissue, filter microorganisms from lymph as it flows through lymph vessels
-large cluster location: axillary lymph nodes, inguinal lymph nodes and cervical lymph nodes
Lymphatic vessels
- extensive network, every body organ has them
- lymph from right arm and right side of head drains to right lymphatic duct
- lymph from rest of body drains into thoracic duct
Spleen
- Largest lymphoid organ
- filters blood and serves as blood reservoir
- organ destroys old RBC, has role in eryhtropoiesis
Tonsils
3 pairs:
- palatine: located opening of oral cavity, removed in tonsillectomy
- pharyngeal (adenoids): located near opening of nasal cavity in upper pharynx, remove when interfere with breathing
- lingual: located back of tongue
Thymus
Mostly active in development of immune system during early life
-produce thymosin for maturation, function of T-cell lymphocyte
Allergy testing
Scratch test, patch test, intradermal test, radioallergosorbent test
Complete blood count
Test profile: hemoglobin, hematocrit, RBC, WBC count
Enzyme linked immunosorbent assay
ELISA
- test for HIV antibodies presence by venous blood, oral fluid sample
- 85% accurate due to cross-activity from other viruses
Liver function
Test measure coagulation factors of prothrombin and fibronogen
WBC differential
Blood test determine percentage of different type of leukocyte present during infection, allergies, certain disease
Western blot
Test specific to individual virus, perform to confirm diagnosis when positive ELISA for HIV found
Allergies
Hypersensitive, result in inflammation may be delayed or immediate, to substance not usually recognize as foreign
Autoimmune disorder
Immune system produce antibodies against own cells
-affects most body systems
Immunodeficiency disease
Congenital or acquired, immune system deficient or incompetent
Severe combined immunodeficiency
Congenital. Children succumb to minor infections
Acquired immunodeficiency syndrome
Most advance stage of infection with HIV virus
-significantly decrease immunity evidence by low T-cells
Systemic lupus erythematosus
Autoimmune disorder, known as lupus
- affect few or many organs systems
- more women than men
- actual cause unknown
- sx: body ache, weight loss, butterfly rash on face, sensitive to sunlight, nosebleed, seizures
Lymphoma
Benign or malignant tumors, affect lymphoid tissue
Hodgkin lymphoma
-malignant with enlarge spleen, lymphocyte known as reed-stern berg cells, occur in young men
Non-Hodgkin lymphoma
All lymphoma other than Hodgkin lymphoma
- may be fast or slow growing
- malignant found throughout lymph tissue
- occur in older adults
Mononucleosis
Mono
- highly contagious viral infection, kissing disease
- from Epstein-Barr virus or cytomegalovirus
- character by extreme fatigue, fever, sore throat, enlarge spleen and lymph tissue
Splenomegaly
Enlarge spleen associated with infectious disease
Maxilla bone
Facial
Upper jaw
Zygomatic bone
Facial bone
Arch of cheek, high portion (cheek bone)
Nasal bone
Facial
-upper part of nose bridge
Palatine bone
Facial
-hard palate of mouth, floor of nose
Duodenum
1st section of small intestine
- 10 inch long
- bile from gallbladder and pancreatic juice
- most digestion, absorption happen here
Jejunum
2nd section of small intestine
- 8 inch long
- some digestion, absorption
Ileum
Last section of small intestine
-12 feet long
Esophageal sphincter
Of stomach: prevent food backing up into esophagus
Fundus
Of stomach: upper portion
Body of stomach
Middle portion
Pylorus
Of stomach: lower end
Pyloric sphincter
Of stomach: regulates rate which partially digested food enters duodenum
Cecum
Of large intestine: blind pouch
- ileum ends, colon begins
- lower part of appendix
Colon
Large intestine
-waste forms, move through by peristalsis
—ascending: right side of ab
—transverse: middle portion
—descending: left side of abdomen
—sigmoid: S shape, connects colon to rectum
Rectum
Connect sigmoid to anus
Anus
Final portion of digestive trace
-feces are excreted here
First degree burn
Superficial burn
- just epidermis
- very little edema
Second degree burn
- partial thickness burn
- involve epidermis, part of dermis
- blistering, edema occurs
Basal cell carcinoma
- located in basal cell layer
- usually found on fair skin individuals
Squamous cell carcinoma
- involve squamous cell layer
- metastasize more quickly
Malignant melanoma
Skin cancer
- most serious type
- occur in melanocytes
- begin with change in mole
- metastasize quickly
Active natural immunity
Produce by body production of antibodies after exposure to disease causing organism
Active artificial immunity
- Acquired from immunization composed of dead/weakened organism
- inactivated toxin
- recombinant DNA
- body produce antibodies to become immune
Passive natural immunity
- Maternal antibodies produced outside of body
- passed on while breastfeeding
- in uterus
Passive artificial immunity
-acquired from immunization composed of antibodies/globulins to fight specific disease-causing organism readily, if exposed
Palatine tonsils
Locate at opening of oral cavity
-usually removed in tonsillectomy
Pharyngeal tonsils
Adenoids
- located opening of nasal cavity in upper pharynx
- pair removed if interfere with breathing
Lingual tonsils
Located at back of tongue
Frontal skull bone
cranium
-Forehead, eye sockets
Temporal bones
Cranium
-side around ear, lower jaw
Parietal bone
Cranium
-side above temporal, top of head
Occipital bone
Cranium
-back of head, skull base
Ethmoid
Cranium
-between nasal cavity, orbits
Sphenoid bone
Cranium
-support nasal cavity
Mandible bone
Facial bone
Lower jaw
Third degree burn
- full thickness burn
- involves all 3 layers
- pale, charred appearance with edema
Carcinoma
Skin cancer