Anatomy 1 Flashcards
3 types of joints
Fibrous (immobile)
Cartilaginous (a bit mobile)
Synovial (vey mobile)
Examples of fibrous joints
Periodontal ligaments Cranial sutures Interosseous membranes (e.g. btw radius and ulna)
In fibrous joints, the bones are connected by…
Fibrous connective tissue - composed of collagen fibres
2 types of cartilaginous joints
Primary (synchondrosis) - hyaline cartilage only
Secondary (symphysis) - hyaline + fibrocartilage
Examples of primary cartilaginous joints (synchondrosis)
epiphysial growth plate in growing long bones
First sternocostal joint
Examples of a symphysis
(secondary cartilaginous)
+ its make up
IV disc
pubic symphysis
bone - hyaline - fibrocartilage - hyaline - bone
Layers of articular/ hyaline cartilage
Articular surface
Superficial/tangential layer
Transitional layer
Bone
Superficial/tangential layer of hyaline cartilage - histology + function
Darker purple
Flattened chondrocytes - produce collagen and glycoproteins (e.g. lubricin)
Collagen fibre orientation = horizontal
Transitional layer of hyaline cartilage - histology and function
Lighter purple
Round chondrocytes - produce proteoglycans (e.g. aggrecan*)
Collagen fibre orientation = vertical
*really good at binding to water - healthy, young cartilage is >75% water which makes it incompressible (protects tissue)
Proteins to which oligosaccharide chains are attached
More of a protein than a carb
Glycoproteins
e.g. lubricin
Proteins that are heavily glycosylated (a protein core with one or more GAGs attached)
Tend to be more carb that protein
Proteoglycans
e.g. aggrecan
Long unbranched polysaccharides which are highly polar and so attract water (help with lubrication)
Glycosaminoglycans (GAGs)
e.g. hyaluronic acid
Characteristics of the synovium
Composed of synoviocytes - produce fluid
Rich capillary network*
No epithelial lining
*O2, CO2 and metabolites are directly exchanged btw blood and synovial fluid
Types of synoviocytes
Type A:
look like macrophages
Remove debris
Contribute to synovial fluid production
Type B:
Fibroblast like
Main producer of synovial fluid
Characteristics of synovial fluid
Viscous like
contains hyaluronic acid and lubricin molecules
Fluid component is from blood plasma
exists in joints in small volumes (~0.5ml in knee)
Has a rapid turnover (~2hours)
Functions of synovial fluid
Nutrition of cartilage + removal of waste products (as cartilage is avascular, aneural + alymphatic)
Lubrication (–> less friction –> less wear)
3 types of lubrication
Boundary:
glycoproteins bind to receptors on articular surfaces to form a thin film
Hydrodynamic (like aquaplaning):
surfaces kept apart by liquid pressure
Weeping:
fluid in the cartilage is squeezed out to increase fluid volume
The co-efficient of friction of a synovial joint (range)
0.002 - 0.02
low number = little friction
The anterior wall of the axilla is formed by the…
Pectoralis major + minor
Subclavius muscles
The posterior wall of the axilla is formed by the…
Subscapularis
Teres major
Latissimus dorsi
The medial wall of the axilla is formed by the…
Thoracic wall
Serratus anterior
The lateral wall of the axilla is formed by the…
Intertubercular groove of the humerus
At what anatomical point does the subclavian artery become the axillary artery?
Lateral border of the 1st rib
At what anatomical point does the axillary artery become the brachial artery?
Lower border of the teres major muscle
Erb’s point location
On the upper trunk
2-3cm above the clavicle on the posterior border of the sternocleidomastoid
Injury to the upper trunk causes…
name, presentation + causes
Erb’s palsy
“Waiter’s tip” appearance of upper limb (medially rotated with wrist flexed)
Causes: fall on the shoulder, birth injury
Which 3 muscles are affected in Erb’s palsy?
Deltoid
Biceps
Brachialis
Injury to the lower trunk causes…
name + muscles affected
Klumpke’s palsy
muscles affected: intrinsic muscles of hand & ulnar flexors of the wrist and fingers
Function of the median cubital vein
A large communicating vein
Shunts blood from the cephalic vein to the basilic vein
The cephalic vein arises from…
The lateral end of the dorsal venous arch
The basilic vein arises from…
the medial end of the dorsal venous arch
All lymphatic vessels from the upper limb drain into…
Axillary lymph nodes (difficult to see in the dissected cadaver)
5 groups of axillary lymph nodes…
Anterior/ pectoral group Posterior/ subscapular group Apical group Central group Lateral group