Anapleorotic Reactions Flashcards
Describe how pyruvate carboxylase is used in the body
- liver, kidney
- activated by AcCoA
- important for FA synthesis
- gluconeogenetic and anaplerotic
What does pyruvate carboxylase convert?
pyruvate –> oxaloacetate
What are the co factors involved in pyruvate carboxylase?
CO2 consumed
ATP –> ADP + Pi
Describe how PEP carboxykinase is used in the body
- heart, muscle
- glucogenetic and anaplerotic
What does PEP carboxykinase convert?
PEP –> oxaloacetate
What are the co factors involved in PEP carboxykinase?
CO2 consumed
GDP –> GTP
Describe how PEP carboxylase is used in the body
- higher plants, yeast, bacteria
- activated by Frc 1,6, bisP
- anaplerotic
What does PEP carboxylase convert?
PEP –> oxaloacetate
What are the co factors in solved in PEP carboxylase?
CO2 consumed
Pi released
Describe how malic enzyme is used in the body
- widely distributed in euks and proks
- importnat for FA synthesis
- anaplerotic
What does malic enzyme convert?
pyruvate –> malate
What are the co factors involved in malic enzyme?
CO2 consumed
NADPH + H+ –> NADP+