ANAPHY P4 SKIN WITH PARTS Flashcards
Basal cells of the epidermis surrounding the wound would break contact with the basement membrane.
what step of epidermal wound healing is this
Step 1
Cells enlarge and migrate across the wound.
what step?
2
Cells migrate as a sheet until advancing sides of opposite sides of the wound meet.
what step of epidermal wound healing
3
Epidermal cells meet, they stop migrating called the CONTACT INHIBITION.
what step is this
Step 4
Migration of the epidermal cells stops completely when each is finally in contact with other epidermal cells on all sides.
Just get it
Stimulates
basal cells to divide and replace the one that
have been moved into the wound.
Epidermal growth factor
● Injury extends to the dermis to the subcutaneous
layer
● Healing process is more complexed because it is
deeper
Deep wound healing
● Blood clots forms in the
wound and loosely unites
the wound edges.
S? Deep wound healing
- Inflammatory
● Neutrophils and monocytes
develops into macrophages
that phagocytize microbes
and mesenchymal cells and
then develops to
FIBROBLASTS
S? deep
1 Inflammatory
● Clot becomes scab
● Epithelial cells migrate
beneath the scab to build a
bridge wound
● Fibroblasts migrate,
damage BV regrows
● Formation of
GRANULATION TISSUE.
What is scab made of?
S?Deep
Step 2 Migratory
Fibrin + Blood component
● Extensive growth of
epithelial cells beneath the
scab
● Continued growth of BV
step?
step 3 proliferative
● Scabs sloughs off once the
epidermis has been
restored to its normal
thickness.
● Collagen fibers become
more organized, fibroblasts
decrease in number, and
blood vessels are restored
to normal.
Step? Deep?
Step 4 Maturation
scar tissue formation
fibrosis
too much
scar tissue is formed during deep
wound healing that a RAISED
SCAR forms.
hyperthropic scar
extends beyond the boundaries
into normal surrounding tissues.
Keloid/Cheloid scar
