ANAPHY P2 SKIN Flashcards

1
Q

functions of the integumentary system

A
  1. Regulates body temperature
  2. Stores blood
  3. Protects body from external
    environment
  4. Detects cutaneous sensations
  5. Excretes and absorbs substances
  6. Synthesizes VITAMIN D
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

• Composed of skin, hair, oil and sweat glands,
nails and sensory receptors

A

Integumentary system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Medical specialty
that deals with the structure, function and
disorders of the integumentary system

A

Dermatologist/Dermatology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

—-

● “—— MEMBRANE”

● Largest organ of body IN
WEIGHT

A

Cutaneous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

MEASUREMENTS: of skin

ADULTS: Skin covers
____meters and weighs _____
(???% of the total body weight)

A

2m^2 in length and 4-5kg in weight, 7%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Thickness of

eyelids
heels
Other body parts (ranges)

A

0.5mm
4mn
1-2mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Superficial
-??? portion
2 Parts

A

• Thinner portion
A. EPIDERMIS
B. DERMIS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

???
Storage depot for fat
and contains blood
vessels that supply the
skin
• Has ??? (sensation of pressure)

A

SUBCUTANEOUS

lamellated
corpuscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Part of subcutaneous

A. ???
(consists of ???
and ??? tissue)

Areolar tissue is ???, contains???, ??? and ??? the provide structural support and helps in the repair of tissue

Adipose tissue serve as a ????, ??? and cushioning of organs

A

A. HYPODERMIS
(consists of areolar
and adipose tissue)

Areolar tissue is highly vascular and contains fibroblasts, macrophages and mast cells

Adipose tissue serve as a energy reserve, insulation and cushioning of organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

EPIDERMIS
● Made up of???

4 principal types of cells

A

keratinized
stratified squamous epithelium

-Keratinocytes
-Melanocytes
-INTRAEPIDERMAL MACROPHAGES/-LANGERHANS
-TACTILE EPITHELIAL
CELLS/MERKEL DISC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Most abundant/common cells in epidermis
-Primary function- produce keratin
-protective protein that helps form the skins barrier shielding the body from environmental damage, such as pathogens, radiation and water loss
-Tough, gives protection to the skin

A

Keratinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Found in the ???? of the epidermis
-primary function: produce the pigment (?)
-accumulates in the keratinocytes of stratum (?) and stratum (?)

A

Melanocytes, basal layer, melanin, stratum basal & stratum spinosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Melanocytes
Brown to black (?) = increase in ??
Yellow to red (?) = decrease in ??

A

eumelanin, melanocytes
pheomelanin, melanocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Melanocytes
Brown to black (?) = increase in ??
Yellow to red (?) = decrease in ??

A

eumelanin, melanocytes
pheomelanin, melanocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

participate in immune
response, help other cells of the
immune system recognize an
invading microbe and destroy it.

A

INTRAEPIDERMAL
MACROPHAGES/LANGERHANS
CELLS -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

detect
touch sensations

A

TACTILE EPITHELIAL
CELLS/MERKEL DISC -

17
Q

PRINCIPAL LAYERS/STRATA OF
CELLS:

A

STRATUM BASALE
STRATUM SPINOSUM
STRATUM GRANULOSUM
STRATUM LUCIDUM
STRATUM CORNEUM

18
Q

Deepest layer
 Single row of ??? or ???
keratinocytes

Contains??? form the tough protein keratin
Contains ??? & ??

Protects deeper layer from injury??

Attach stratum basale to stratum spinosum? so therefore this layer contains?

Attach epidermis and dermis? so this layer contains

A

Stratum basale, cuboidal & columnar, KERATIN INTERMEDIATE
FILAMENTS

Merkel cells and melanocytes

Keratinocytes

Desmosomes
Hemidesmosomes

19
Q

 Superficial to stratum basale
 With coarse bundles of keratin in
intermediate filaments
 Cells shrink and pull apart
appearing like thornlike spines
 Provides strength and flexibility of
skin

??? act as a part of the immune system to scavenge foreign proteins that invade epidermis

A

Stratum spinosum , Langerhans cells

20
Q

 Middle of epidermis
 With ?-? layers of keratinocytes
undergoing ???

__________________________
- assembles
keratin intermediate filaments to keratin

___________________________
-fuses
plasma membrane and release lipid-rich
secretion

A

Stratum Granulosum, 3-5 layers undergoing apoptosis

Keratinohyalin
Lamellar/Lameliated granules

21
Q

 Present only in the thick skin (fingertips,
palms and soles
 ?-? layers of flattened, clear and dead
keratinocytes (with thick plasma
membranes)
 Provides an additional level of toughness
in this region of the skin

A

Stratum lucidum, 4-5 layers

22
Q

Cells are extremely thick, flat, plasma
membrane-enclosed packages of keratin
 Final product of the process of
keratinocytes
 Cells overlap one another like the scales
on the skin of a snake
_________ - constant exposure of skin to
friction (increased cell and keratin
production)

A

Stratum corneum, Callus

23
Q

Composition: dense irregular connective
tissue containing ??? and ??
● Has the ability to stretch
and recoil easily
● Blood vessels, nerves,
glands and hair follicle

???= collagen: strength and d roughness, ability to stretch

???= elastic fibers, flexibility and stretch (ability to return to its original shape)

A

Dermis, collagen & elastic
fibers

extensibility, elasticity

24
Q

Superficial region of dermis

—-small, nipple-shaped
structures that project into the
undersurface of the epidermis (with
capillary loops/blood vessels) this forms dermal ridges that form our fingerprints, palm prints and footprints

—-nerve endings sensitive to touch (warmth,
coolness, pain, tickling and itching)

A

Papillary region

Dermal papillae, Meissner corpuscle

25
Q

Deeper region of dermis
• Contains bundles of thick collagen fibers,
scattered fibroblasts and various
wandering cells.

• _______________: arranged in a netlike
manner (helps the skin resist stretching)
• _____________________________: provides
strength, extensibility, ability to stretch,
and elasticity.

A

Reticular region, Collagen fibers, collagen and elastic fibers

26
Q

Macrophages
??? reside in a specific tissue and remain relatively stationary

??? circulate in the bloodstream and migrate to various tissue in response to infection or injury

A

fixed, wandering (free)

27
Q

2 layers of the dermis

A

papillary and reticular region