ANAPHY M6 2 Flashcards
“Cutaneous membrane”
Largest organ of the body in weight
SKIN
superficial, thinner portion, composed of epithelial tissue, avascular
Develops from ectoderm
EPIDERMIS
deeper, thicker connective tissue portion, vascular
Develops from mesoderm
DERMIS
Keratinized stratified squamous epithelium
EPIDERMIS
produce the protein keratin & lamellar granules
KERATINOCYTES
pigment producing cells
MELANOCYTES
composed of a single row of cuboidal or columnar keratinocytes & stem cells to continually produce new keratinocytes “stratum germanativum”
Melanocytes and tactile epithelial cells
STRATUM BASALE
consists of numerous keratinocytes (8–10 layers)
Coarser keratin
provides both strength and flexibility to the skin
STRATUM SPINOSUM
flattened keratinocytes that are undergoing apoptosis (3-5 layers)
lamellar granules fuse with the plasma membrane and release a lipid-rich secretion — acts as a water-repellent sealant
transition between metabolically active strata and the dead cells
STRATUM GRANULOSUM
present only in the thick skin (palms, soles, palmar surface of the digits, plantar surface of toes)
flattened clear, dead keratinocytes that contain large amounts of keratin and thickened plasma membranes (4-6 layers)
STRATUM LUCIDUM
25 to 30 layers of extremely flattened dead keratinocytes
final product of the differentiation process of the keratinocytes
protect deeper layers from injury and microbial invasion
STRATUM CORNEUM
abnormal thickening due to repeated friction
Callus
dense irregular connective tissue containing collagen and elastic fibers— great tensile strength (resists pulling or stretching forces)
Cells present: fibroblasts, macrophages, few adipocytes, Blood vessels, nerves, glands, and hair follicles (epithelial invaginations of the epidermis) are embedded in the dermal layer
dermis
consists of areolar connective tissue with thin collagen and fine elastic fibers; dermal ridges that house blood capillaries, tactile corpuscles, and free nerve endings
PAPILLARY DERMIS
consists of dense irregular connective tissue with bundles of thick collagen and coarse elastic fibers; adipose cells, hair follicles, nerves, sebaceous glands, and sudoriferous glands
RETICULAR DERMIS