Anaphy Flashcards
Muscular System
Identify the property of muscle:
The ability of muscle to shorten forcefully, or contract
Contractility
Identify the property of muscle:
The capacity of muscle to respond to a stimulus
Excitability
Identify the property of muscle:
The ability to be stretched beyond its normal resting length and still be able to contract
Extensibility
Identify the property of muscle:
The ability of the muscle to recoil to its original resting length after it has been stretched
Elasticity
Identify the type of muscle:
- attached to bones
- striated; transverse bands
- voluntary controlled
Skeletal
Identify the property of muscle:
- located in the heart
- striated
-involuntary controlled
Cardiac
Identify the property of muscle:
- located in blood vessels, hollow organs
- non - striated; visceral
Smooth
Each skeletal muscle is surrounded by a connective tissue sheath called the
Epimysium
A skeletal muscle is subdivided into groups of muscle cells called
Fascicles
Each fascicle is surrounded by a connective tissue covering, termed the
Perimysium
Each skeletal muscle cell (fiber) is surrounded by a connective tissue
covering, termed the
Endomysium
- is a single cylindrical cell, with several nuclei located at
its periphery - range in length 1 cm to 30 cm and are generally 0.15mm in diameter
Muscle fiber
Another word for cell membrane that has many tubelike inward folds
Sarcolemma
In Sarcolemma this is the tubelike inward folds also known as transverse tubules
T tubules
The T tubules are associated with enlarged portions of smooth endoplasmic reticulum called the
Sarcoplasmic reticulum
The enlarged portions of of muscle fiber structure are called
Sarcoplasmic reticulum
T tubules connect the sarcolemma to the terminal cisternae to form a
Muscle triad
The sarcoplasmic reticulum has a relatively high concentration of ____ which plays a major role in muscle contraction
CA+2
- The cytoplasm of a muscle fiber is called the _____ which contains many bundles of protein filaments
Sarcoplasm
Bundles of protein filaments are called
Myofibrils
Myofibrils consist of the ____, -______, _______
Myofilaments, actin, and myosin
Is the basic structural and functional unit of a skeletal
muscle because it is the smallest portion of a skeletal muscle capable of contracting
Sarcomere
Form a network of protein fibers that both serve as an anchor for
actin myofilaments and separate one sarcomere from the next
Z disks
A sarcomere extends from one ____ to the next
Z disk
Light bands, consist only of actin, and are called _______ that extends
toward the center of the sarcomere to the ends of the myosin myofilaments
I bands
Dark staining bands are called ______, , that extend the length of the myosin myofilaments
A bands
Actin and myosin myofilaments overlap for some distance on both ends of the A band; this overlap causes the ______
contraction
Actin myofilaments are made up of three components: ______, ______, ______
Actin, troponin, and tropomyosin
This molecules have binding sites for Ca2+
Troponin
This filaments block the myosin myofilament binding sites on the actin myofilaments
Tropomyosin
They have ATP binding sites, ATPase and attachment spots for
actin
Myosin heads
The electrical charge difference across the cell membrane of an
unstimulated cell is called the
Resting membrane potential
The resting membrane potential is due to the inside of the membrane being ______ charged in comparison to the outside of the membrane
being _______ charged
negatively, positively
Are due to the membrane having gated channels
Action potentials
The resting membrane potential exists because of
- The concentration of K+ being higher on the inside of the cell membrane and the
concentration of Na+ being higher on the outside - The presence of many negatively charged molecules, such as proteins, inside the
cell that are too large to exit the cell - The presence of leak protein channels in the membrane that are more permeable to
K+ than it is to Na+
In order to maintain the resting membrane potential, the sodium potassium pump recreates the ion gradient by pumping _____ out of the cell and ___ into the cell
Na+, K+
To initiate a muscle contraction, the ______ must be changed to _______
resting membrane potential, action potential
This increase in positive charge inside the cell membrane is called
Depolarization
If the depolarization changes the membrane potential to a value called ___, an action potential is triggered
Threshold
Opening of gated K+ channels starts ______ of the cell membrane
Repolarization
Enumerate the steps of Action potential
- Resting membrane potential
- Depolarization
- Repolarization
A _____ neuron is a nerve cell stimulates muscle cells
Motor
is a synapse where a the fiber of a nerve connects with a muscle fiber
Neuromuscular
refers to the cell-to-cell junction between a nerve cell and
either another nerve cell or an effector cell, such as in a muscle or a gland
Synapse
is a group of muscle fibers that a motor neuron stimulates
Motor unit
is the end of a neuron cell axon fiber
Presynaptic terminal
is the space between the presynaptic terminal and
postsynaptic membrane
Synaptic cleft
is the muscle fiber membrane
Postsynaptic membrane
is a vesicle in the presynaptic terminal that stores
and releases neurotransmitter chemicals
Synaptic vesicle
are chemicals that stimulate or inhibit postsynaptic
cells
Neurotransmitters
is the neurotransmitter that stimulates skeletal muscles
Acetylcholine
Enumerate the steps of Muscle Contraction
- An action potential
travels down motor
neuron to presynaptic
terminal causing Ca2+
channels to open - Ca2+ causes synaptic
vesicles to release
acetylcholine into
synaptic cleft - Acetylcholine binds to
receptor sites on Na+
channels, Na+ channels
open, and Na+ rushes into
postsynaptic terminal
(depolarization) - Na+ causes sarcolemma
and t-tubules to increase
the permeability of
sarcoplasmic reticulum
which releases stored
calcium - Ca2+ binds to
troponin which is
attached to actin - Ca2+ binding to
troponin causes
tropomyosin to
move exposing
attachment sites for
myosin - Myosin heads bind to
actin - ATP is released from
myosin heads and heads
bend toward center of
sarcomere - Bending forces actin to
slide over myosin - Acetylcholinesterase
(enzyme breaks down
acetylcholine) is
released, Na+ channels
close, and muscle
contraction stops
- Energy for muscle contractions is supplied by this
- stored in myosin heads
- help form cross-bridge formation between myosin and actin
ATP
Will occur when a person dies and no ATP is available to release cross-bridges
Rigor mortis
Is a single contraction of a muscle fiber in response to a stimulus
Muscle twitch
Enumerate the 3 phases of muscle twitch
Latent phase, contraction phase, and relaxation phase
Muscle twitch phase:
is the time between the application of a stimulus and the beginning of contraction
Latent phase
Muscle twitch phase:
is the time during which the muscle contracts
Contraction phase
Muscle twitch phase:
is the time during which the
muscle relaxes
Relaxation phase
In ______, individual muscles contract more forcefully
Summation
is a sustained contraction that occurs when the frequency of
stimulation is so rapid that no relaxation occurs
Tetanus
is the stimulation of several motor units
Recruitment
Twitch fiber:
- contract slowly
- fatigue slowly
- have a considerable amount of myoglobin
- use aerobic respiration
- are dark in color
- used by long distance runners
Slow twitch fibers
Twitch fiber:
- contract quickly
- fatigue quickly
- use anaerobic respiration
- energy from glycogen
- light color
- used by sprinters
Fast twitch fibers
Energy comes from either ____with O2 or_____ without O2
aerobic, anaerobic
ATP is derived from 4 processes in skeletal muscle which are?
- Aerobic production of ATP during most exercise and normal conditions.
- Anaerobic production of ATP during intensive short-term work
- Conversion of a molecule called creatine phosphate to ATP
- Conversion of two ADP to one ATP and one AMP (adenosine monophosphate) during heavy
exercise
Mechanisms of fatigue include:
- Acidosis and ATP depletion due to either an increased ATP consumption or a decreased ATP production
- Oxidative stress, which is characterized by the buildup of excess reactive oxygen species (ROS; free
radicals) - Local inflammatory reactions
Type of muscle contraction:
Has an increase in muscle tension, but no change in length
Isometric contraction
Type of muscle contraction:
Has a change in muscle length with no change in tension
Isotonic contraction
Type of muscle contraction:
are isotonic contractions in which muscle tension increases as
the muscle shortens
Concentric contractions
Type of muscle contraction:
are isotonic contractions in which tension is maintained in a
muscle, but the opposing resistance causes the muscle to lengthen
Eccentric contractions
- Is the constant tension produced by body muscles over long
periods of time - is responsible for keeping the back and legs straight, the head in an upright position, and the abdomen from bulging
Muscle tone
Are non-striated small, spindle-shaped muscle cells,
usually with one nucleus per cell
Smooth muscle cells
- are long, striated, and branching, with usually only one
nucleus per cell - is striated as a result of the sarcomere arrangement
- contraction is autorhythmic
Cardiac Muscle
Cardiac muscle cells are connected to one another by specialized structures
that include desmosomes and gap junctions called
Intercalated disks
Connects skeletal muscle to bone
Tendon
Are broad, sheetlike tendons
Aponeuroses
is a band of connective tissue that holds down the tendons at each wrist and ankle
Retinaculum
Skeletal muscle attachments have an origin and an insertion, with the ____ being the attachment at the least mobile location
origin
The ______ is the end of the muscle attached to the bone undergoing the greatest movement
Insertion
The part of the muscle between the origin and the insertion is the
Belly
A group of muscles working together are called
Agonists
A muscle or group of muscles that oppose muscle actions are termed
Antagonists
A muscle that crosses on the anterior side of a joint produces
Flexion
A muscle that crosses on the posterior side of a joint produces
Extension
A muscle that crosses on the lateral side of a joint produces
Abduction
A muscle that crosses on the medial side of a joint produces
Adduction
Movement: touches tip of another finger
Opposition
Muscles are named according to:
- Location
- Size
- Shape
- Orientation of fascicles
- Origin and insertion
- Number of heads
- Function
Fan- shaped muscle that covers parts of the temporal, frontal, and parietal bones
Temporalis
Powerful muscle that covers lateral aspect of mandibular ramus
Masseter
Deep two=headed muscle that runs along internal surface of mandible and is largely concealed by that bone
Medial pterygoid
Deep two-headed muscle; lies superior to medial pterygoid muscle
Lateral pterygoid
Elevate ribs for inspiration
External intercostals
Depress ribs during forced expiration
Internal intercostals
Moves during quiet breathing
Diaphragm
- center of abdomen
- compresses abdomen
Rectus abdominis
- sides of abdomen
- compresses abdomen
External abdominal oblique
Compresses abdomen (2)
Internal abdominal oblique and Transverse abdominis
Integration and control systems (Special Senses)
Traditional smell, taste, sight, and hearing
Special Senses
Either large, complex sensory organs or localized clusters of receptors
Special sense receptors
The accessory structures of the eye include what?
extrinsic eye muscles, eyelids, conjunctiva, and lacrimal apparatus
Anteriorly the eyes are protected by the
Eyelids
The eyelids meet at the medial and lateral corners of the eye which are
Medial commisure and Lateral commisure
Projecting from the border of each eyelid are the
Eyelashes
Modified sebaceous glands associated with the eyelid edges are the
Tarsal glands
Modified sweat glands that lie between the eyelashes
Ciliary glands
A delicate membrane that lines the eyelid and covers part of the outer surface of the eyeball that secretes mucus
Conjunctiva
Inflammation of the conjunctiva results in reddened, irritated eyes
Conjunctivitis
Its infectious form caused by bacteria or viruses, is highly contagious
Pinkeye
Consist of the lacrimal gland and a number of ducts that drain lacrimal secretions into the nasal cavity
Lacrimal apparatus
Located above the lateral end of each eye that continually release a dilute salt solution onto the anterior surface of the eyeball through several small ducts
Lacrimal glands
The tears flush across the eyeball medially into the
lacrimal sac
After going through the lacrimal sac the eyeball will go into this which empties into the inferior meatus of the nasal cavity
Nasolacrimal duct
Enzyme that destroys bacteria
lysozyme
What muscle produce gross eye movements and make it possible for the eyes to follow a moving object
Extrinsic eye muscles
How many extrinsic eye muscle are attached to the outer surface of each eye.
6
The eyeball has walls that is composed of 3 ____ and its interior is filed with fluids called _____
tunics and humors
The outermost layer of the eye is called
fibrous layer
The fibrous layer consists of the protective ____ is seen anteriorly as the white of the eye
Sclera
The fibrous layer consists of the transparent ___ which is the central anterior portion “window” which light enters the eye
cornea
The middle layer of the eye
vascular layer
The most posterior part of the vascular layer that is a blood-rich nutritive tunic that contains a dark pigment
Choroid
Anterior part of the vascular layer with two smooth muscle structures
Ciliary body
Part of the vascular layer which is a suspensory ligament called the
ciliary zonule
Part of the vascular layer with pigment and a rounded opening through which light passes
iris and pupil
Innermost layer of the eye
Sensory layer
Part of the sensory layer which is the delicate two-layered ___ which extends anteriorly only to the ciliary body
retina
The transparent inner neutral layer of the retina contains millions of receptor cells, the rods, and cones, which are called
photoreceptors
Electrical signals pass from the photoreceptors via two neuron chain
Bipolar cells and Ganglion cells
The photoreceptor cells are distributed over the entire retina, except where the optic nerve leaves the eyeball; this site is called the. There are no photoreceptors here
optic disc
A tiny pit that contains only cones lateral to each blind spot. This is the area of greatest visual activity
Fovea centralis
Crystal-like structure that bends light rays so they focus on the retina
Lens
If light is not focused on the lens what eye problems may occur?
Myopia, hyperopia, or astigmatism
The anterior chamber which is similar to blood plasma. Is reabsorbed into the scleral venous sinus
Aqueous humor
The posterior chamber contains this gel-like fluid posterior to lens
Vitreous humor
Pathway of light through the eye
- Cornea
- aqueous humor
- pupil
- lens
- vitreous humor
- retina
The shape of the lens is adjusted during the process of
Accommodation
The site where medial fibers from each eye cross over to the opposite side of the brain
Optic chiasma
Pathway of nerve impulses from the retina steps
- optic nerve
- optic chiasma
- optic tract
- thalamus
- optic radiation
- visual cortex
- occipital lobe of brain
3 Eye reflexes
Eye reflexes include the photo pupillary reflex, accommodation pupillary reflex, and convergence
Respond to physical movement in order to detect a stimulus and send an impulse
Mechanoreceptors
The external ear includes: which is involved with sound transmission only
- Auricle
- External acoustic meatus
- Tympanic membrane
Part of the external ear that secretes waxy cerumen to protect the ear canal
Ceruminous glands
The middle ear cavity includes: which is involves with sound transmission only
- Ossicles
- Pharyngotympanic tube
Transmit and amplify vibratory motion from the eardrum to the oval window
Auditory ossicles
Allows pressure to be equalized on both sides of the eardrum
Pharyngotympanic tube
Internal ear consists of: which is involves in both hearing and equilibrium
- Bony labyrinth
- cochlea vestibule
- semicircular canals
Bony labyrinth contains _____; membrane labyrinth contains ______
Perilymph, Endolymph
In the cochlear duct, the spiral organ of Corti has hearing receptors called. They are anchored to the basilar membrane, and are embedded in a tectorial membrane
hair cells
Equilibrium receptors in inner ear that respond to head movements with respect to the pull of gravity
Vestibular apparatus
Report on head movements when body is not moving
Static equilibrium
Receptors in the vestibule are called
maculae
Are embedded on the surface of otolithic membrane which move in response to body movement with respect of pull of gravity
Otoliths
Report on rotational movements of the head
Dynamic equilibrium
Receptors in the ampullae of the semicircular canals are called
Crista ampullaris
The tufts of hair cells with hair embedded in gel cap in Crista
Cupula
Any degree of hearing loss
Deafness
Something interferes with transmission of sound waves
Conduction deafness
Fusion of the middle ear ossicles, resulting in conduction deafness
Otosclerosis
Something interferes with receptors or neural transmission of impulses to the brain
Sensorineural deafness
Result in nausea, dizziness, problems maintaining balance
Equilibrium problems
Results in progressive deafness and vertigo
Meiniere’s syndrome
Respond to dissolved chemicals
Chemoreceptors
Located in the superior aspect of each nasal cavity
Olfactory receptors
Closely linked to the limbic system; odors stimulate the recall of memories and arouse emotional responses
Olfactory pathways
Are located in the taste buds
Gustatory cells
True or False:
Special sense organs from early in embryonic development
True
Congenital eye problem resulting from unequal pulling by extrinsic eye muscles that result in crossed eyes
Strabismus
Most important congenital ear problem
Absence of the external acoustic meatus
Normal consequence of aging
Sensorineural deafness or presbycusis
Renal System (Urinary System)
Arteries and veins, arterioles and venules
Vascular System
Clear Part of the blood
Plasma
Obtained when blood is separated in the laboratory
Serum
Component of the blood without the plasma
Whole Blood
Composed of red cell, white cells, platelets, etc.
Blood
Function of the Kidney:
Remove waste and toxic substances in the blood (metabolic by-products of cells and substances)
Excretory Organs
Excretion of metabolic wastes:
Breakdown of creatine phosphate in muscle fibers
Creatinine
Excretion of metabolic wastes:
Breakdown of proteins
Urea
Excretion of metabolic wastes:
By product of proteins/ amino acids
Ammonia (NH3)
Excretion of metabolic wastes:
Breakdown of hemoglobin
Bilirubin
Excretion of metabolic wastes:
Breakdown of nucleic acid
Uric Acid
Function of the Kidney:
By control of extracellular fluid volume (Renin) and urine concentration (osmolality)
Regulator of blood volume and blood pressure
Function of the Kidney:
Glucose, sodium, potassium, chloride, bicarbonate, phosphate, calcium
Regulation of solutes and ions in the blood plasma
Function of the Kidney:
PH (acidity and alkalinity)
Regulator of the Body fluid PH
Function of the Kidney:
Cell synthesis (Erythropoietin)
Regulator of the red blood cell synthesis
Function of the Kidney:
final conversion of its active form 1,25 DIHYDROCHOLECALCIFEROL (Calcitriol)
Synthesis of Vitamin D
- known as renal in Latin
- bean shaped
- adipose tissues holds it in place
Kidney
Location of Kidney
- posterior location
- costovertebral angle
- 12h rib
- 1st 3 lumbar spine
Behind the peritoneum
Retroperitoneal
True or False:
The left kidney is lower than the right kidney
False: The right kidney is lower than the left kidney
Connective tissue (fibrous) that surrounds and protect the kidney
Renal Capsule
Medial indentation on each side of the kidney where vessels or nerves enter or exit
Hilum
Fat filled cavity which contains the blood vessels
Renal Sinus
Wide section of the urinary channel
Renal Pelvis
- Cup of a flower
- funnel shape branch of the renal pelvis
Calyx
Outer Renal Parenchyma
Cortex
Inner Renal Parenchyma
Medulla
Cone shaped sections of tissue lying mostly in the medulla
Renal Pyramids