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Pharm > Analgesia > Flashcards

Analgesia Flashcards

0
Q

Fentanyl/Sublimaze/Duragesic

P-Dyn

A

Combines with brain receptor sites to produce analgesia
-Decreased pain perception (mu, kappa, delta)
Mostly Mu

Decreased emetic effect

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1
Q

Fentanyl/Sublimaze/Duragesic

Class

A

Opioid analgesic

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2
Q

Fentanyl/Sublimaze/Duragesic

Indications

A

Analgesia

Sedation for airway (combo with other agents)

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3
Q

Fentanyl/Sublimaze/Duragesic

Adverse/Side Effects

A

Triad (MBP)
Brady
Hypotension
N/V, constipation

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4
Q

Fentanyl/Sublimaze/Duragesic

Contraindications

A

Allergy
Head injury/CNS depression/ICP
Myasthenia gravis
MAO inhibitors within 14 days

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5
Q

Fentanyl/Sublimaze/Duragesic

Precautions

A

Old, respiratory, seizures, cardiac

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6
Q

Fentanyl/Sublimaze/Duragesic

Interactions

A

CNS depressants
Potentiated by benzos
MAO inhibitors precipitate HTN crisis

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7
Q

Fentanyl/Sublimaze/Duragesic

Dose

A

May dilute
25-200 mcg slow IV
50-100 mcg IM q 30-60 min PRN

1-2 mcg/kg slow IV/IM q 5-15 min PRN

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8
Q

Fentanyl/Sublimaze/Duragesic

Peds dose

A

1-2 mcg/kg slow IV q 5-15 min PRN

1-2 mcg/kg IM q 15-60 min PRN

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9
Q

Meperidine/Demerol

Class

A

Narcotic analgesic

Opioid

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10
Q

Meperidine/Demerol

P-Dyn

A

Analgesia (pain perception, catecholamine production)
Decreased myocardial O2 demand
Lacks hemodynamic morphine effects

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11
Q

Meperidine/Demerol

Indications

A

CP suggestive of AMI, unresponsive to nitrates

Mod/severe musculoskeletal pain

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12
Q

Meperidine/Demerol

A/S

A

Triad
Hypotension
N/V
Constipation

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13
Q

Meperidine/Demerol

Contraindications

A

MAOIs (Nardil, Parnate)
SSRI (Paxil,Prozac, Zoloft, Luvox)

Allergy
Hypovolemia, hypotension
Head injury, CNS depression, ICP
Abd pain

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14
Q

Meperidine/Demerol

Interactions

A

Increased effects with CNS depressants
Dilantin/Phenytoin blunts effects
Enhanced with lots of meds

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15
Q

Meperidine/Demerol

Dose

A

25-50 mg slow IV q 1 hr PRN

50-100 mg IM q3-4h PRN

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16
Q

Meperidine/Demerol

Peds Dose

A

1-2 mg/kg slow IV/IM

17
Q

Hydromorphone/Dilaudid

Class

A

Opioid analgesic

18
Q

Hydromorphone/Dilaudid

P-Dyn

A

Combines with Mu receptors in brain to produce analgesia

Decreases perception of pain

19
Q

Hydromorphone/Dilaudid

Indications

A

Mod/severe pain

Antitussive

20
Q

Hydromorphone/Dilaudid

A/S

A

Triad
Brady
Hypotension
N/V, constipation

21
Q

Hydromorphone/Dilaudid

Contraindications

A

Allergy
Head injury, CNS depression, ICP
Asthma

22
Q

Hydromorphone/Dilaudid

Precautions

A

7-10 x morphine

Old, resp, seizure disorders

23
Q

Hydromorphone/Dilaudid

Interactions

A

Increased with CNS depressants, TCAs, phenothiazines, benzos

24
Q

Hydromorphone/Dilaudid

Dose

A

1-2 mg slow q 6-8 hrs

25
Q

Toradol/Ketorolac Tromethamine

Class

A

NSAID

26
Q

Toradol/Ketorolac Tromethamine

P-Dyn

A

Non-opiate analgesia

  • inhibits prostaglandin synthesis
  • decreases responsiveness of pain receptors in inflamed tissue
  • peripheral acting
27
Q

Toradol/Ketorolac Tromethamine

Indications

A

Mod/Severe pain

28
Q

Toradol/Ketorolac Tromethamine

A/S

A

Bleeding, abd pain, diarrhea, nausea
Swelling, anaphylaxis
Increased BP
Drowsiness

29
Q

Toradol/Ketorolac Tromethamine

Contraindications

A

Allergy (incl. ASA NSAIDs)
Active ulcers/GI bleed
Renal failure
Head bleed

30
Q

Toradol/Ketorolac Tromethamine

Precautions

A

IM typical route, single dose
Caution in renal/hepatic impairment
Reduced dose in above and elderly

31
Q

Toradol/Ketorolac Tromethamine

Interactions

A

Increased bleeding with anticoagulants
Increased lithium levels
Reduces Lasix effectiveness

32
Q

Toradol/Ketorolac Tromethamine

Dose

A 
IM
60 mg (normal)
30 mg (over 65, renal, less than 50 kg)
IV
30 mg (normal) 
15 mg (over 65, renal, less than 50 kg)
No peds
33
Q

Adjuvant analgesic

A

Enhance efficacy of opioids
Treat underlying causes
Reduce side effects

34
Q

Nalmefene/Revex

Class

A

Narcotic/opiate antagonist

Competitive antagonist

35
Q

Nalmefene/Revex

P-Dyn

A

Competes for narcotic/opiate receptors

Reverses narcotic effects

36
Q

Nalmefene/Revex

Indications

A

Narcotic OD

37
Q

Nalmefene/Revex

A/S

A

Withdrawal -HTN, tachycardia, violent behavior, tremors, seizures
Arrhythmias
N/V

38
Q

Nalmefene/Revex

Contraindications

A

Allergy

39
Q

Nalmefene/Revex

Interactions

A

Poss. increased risk of seizures if used with Flumazenil

40
Q

Nalmefene/Revex

Dose

A

1st 0.5 mg/70 kg
2nd q2-5, 1 mg/70 kg

With addicts start with 0.1 mg/70 kg
No peds

Pharm (13 decks)

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