Anaesthetics-Principles and Pharmacology Flashcards
what does anaesthesia mean
without feeling/perceptioon
what is general anaestehtsa
produces insensibiltyto the whole body- implies loss oc consciousness and global lack of awareness
what is regional
nerve and plexus blocks including spinal and epidrual
what is local
directly into the tissue
what are the different effects of anaesthetics
analgesia
relaxation
hypnosis
what are the different types
local
muscle relaxants
general
opiates
what are the problems
polypharmacy
muscle relaxation requires ventilation
what does general anaesthetic provde
hypnosis
relaxation
what is the action of general
hyperpolarise neurons so make it more difficulty to sire and send signals to the brain
inhalation dissolve in membrane
IV-allosteric binding
what is the effect of IV
rapid onset rapid recovery metabolism of the drugs meaning its being destroyed and removed from body fat soluble blood first then muscle then fat
what is the effect of IH
halogenated hydrocarbons taken up and excreted by lungs lungs to blood to brain achieves high partial pressure induction is slow awakening with no agent gas
what’s the effect of muscle relaxants
paralyse skeletal muscle
when immobility it essential
awareness
what is the physiology of GA
depress CV centre-vasodilation
what is the physiology of GA
depress CV centre-vasodilation
