Anaesthetics and A&E Flashcards

1
Q

Initial management of acute patient

A

ABCDE

Airway
- Secure airway (Guedel, NP airway, LMA (i-gel), ET tube

Breathing

  • Check RR
  • O2, neb salbutamol/Ipratropium bromide

Circulation

  • BP, HR, Cap refill, urine output
  • Fluid resus, vasopressors, cathertirisation

Disability

  • Do GCS, AVPU, cap glucose,
  • CT, IV glucose if needed

Exposure
- Rashes, burns etc

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2
Q

What scoring system used to determine CT post neck injury

A

Canadian C spine score

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3
Q

Canadian C-spine indicators for Radiography

A
Age over 65
Dangerous mechanism
Parasthesia 
Immediate pain, C-spine tenderness
Unable to rotate 45 degrees L and R
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4
Q

AVPU

- What does this assess

A

Patient response:

Awake
to Voice
to Pain
Unresponsive

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5
Q

Burns:

  • Who are high risk
  • Initial assessment
A

Under 5 and over 75 yrs

ABCDE (prevent hypothermia) ± need for fluid resus

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6
Q

Burns rule of 9s

A
Head 9%
Each arm 9%
Torso front 18%
Torsa back 18%
Each leg 9%
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7
Q

Hand as % body surface area

A

1%

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8
Q

5 Burn thickness

A

1) Epidermal (superficial partial thickness)
2) Superficial dermal
3) Deep dermal
4) Full-Thickness (third degree)
5) Fourth degree

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9
Q

Superficial epidermal/dermal features

A

Pain, red, no/small blistering, brisk cap refill,

Healing 1-3 week, minimal scarring

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10
Q

Full thickness burn features

A

White/black, dry, no blistering, no cap refill, no sensation/pain

Tx: requires surgical excision and graft.

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11
Q

What is fourth degree burn?

A

Includes sub cut fat/muscle/bone.

May need Reconstruction/amputation

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12
Q

What is the problem with burns assessment

A

They are DYNAMIC. Need reassessment in 24-72hrs

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13
Q

Ix in burns

A

Bloods: Serum glucose, Crossmatch, U&E

CXR: Dysrhythmia and electrolyte disturbance

Circulation: BP may be low, monitor urine

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14
Q

Burn management

A

Stop burning (remove stimulus, chemical/clothing etc) and cool site

Minor burns - Dress, analgesia, ABX (fluclox) if infected

Major: ABC

  • A: look for inhalation injury, May need ET intubation (stridor due to airway oedema in inhalation inj)
  • Breathing for inhalation, CO poisoning. COHb levels
  • C: Fluid loss (vasodilation = inc cap permeability)). Fluid replace 15% Body SA burns adults and 10% in children
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15
Q

Parkland formula for fluids in burns

A

4ml/kg/% body area

Hartmann’s

50% first 8 hours
50% second 16 hours

Children then also get 4/2/1 maintenance per hour

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16
Q

Burns when to refer

A

Under 5 or Over 60yrs

Site: Face, hands, perineum (risk forneirs), flexure, circumferential

Inhalaiton injury

Over 5% child under 16
Over 10% in someone over 16

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17
Q

Flail Chest

  • Mech
  • what is seen
  • Assoc with
A

3+ ribs broken in 2 + places due to trauma and detached from rest of the chest

Paradoxical breathing - in-drawing on inspiration

Pulmonary contusions - haemothorax
Punctured lung - pneumothorax

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18
Q

Flail chest management

A

Positive pressure ventilation (note intubation may worsen tension pneumothorax)

Pain control - intercostal blocks

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19
Q

Reversible causes of cardiac arrest (5H’s, 4T’s)

A
Hypoxia
Hypovolaemia
Hypo/Hyperkaaemia
Hypothermia
H+ (acidosis)

Thrombosis (coronary/pulmonary)
Tamponade
Toxins
Tension Pneumothorax

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20
Q

Major haemorrhage Lethal triad (similar to what kills you in shock)

A

Hypothermia

Acidosis

Coagulopathy of trauma

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21
Q

What kills you in shock?

A

Hypothermia

Acidosis

Coagulopathy (e.g. DIC)

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22
Q

Major haemorrhage management

A

Stop bleeding:
- splint, pressure, haemostat agent (tranexamic acid IV), REBOA (aortic occlusion balloon)

Replace fluids lost:
- Fluids + Blood + Blood products (FFP, cryoprecipitate)

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23
Q

Major haemorrhage protocol:

A

RBC 4 units

FFP 4 units

Platelets 1 unit

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24
Q

GCS

  • Three categories
  • How many points per
A

Eye opening response (4)

Verbal response (5)

Motor response (6)

Max score: 15
Min score: 3

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25
Q

GCS - Eye opening

A

Spontaneously
To verbal command
To pain
None

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26
Q

GCS - Verbal response

A
Oriented
Confused conversation
Inappropriate words
Sounds
None
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27
Q

GCS - Motor

A
Obeys command
Moves toward pain
Withdraws from pain
Spastic flexion
Extensor response
No motor
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28
Q

BUFALO

A
Bloods
Urine (vol and culture)
Fluids
Abx
Lactate
Oxygen
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29
Q
Status epileptics:
Drug:
- No IV access
- IV access
- If not effective
A

Buccal Midaz

Lorazepam

Phenytoin

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30
Q

Wernickes (reversible)

A

Ophthalmoplegia
Encephalopathy
Ataxia

31
Q

Korsakoffs

non-reversible

A

Aterograde/Retrograde amnesia

Confabulation

32
Q

What to give in Alcoholic presenting to A&E

A

PAbrinex: prevent Wernickes/Korsakoffs

33
Q

Delerium tremens

A

Coarse tremor
Confusion
Visual hallucinations (Lilliputian), formication
Seizures

34
Q

Anaphylaxis

  • Type of reaction
  • Mech
A

Type 1

Antigen binds to IgE on mast cells of sensitised individuals

Mast cell degranulation (histamine, thromboxjnes PG, Leukotrienes, Pt activators - bradykinins)

Vasodilation & Inc permeability
Bronchospasm

35
Q

Anaphylaxis features

A

Respiratory - swollen lips, tongue, pharynx, epiglottis
Lower - wheeze, chest tightness,
dyspnoea

Skin - pruritus, erythema, urticarial rash, angio-oedema

CVS - increased permeability leading to hypotension —> anaphylactic shock

GI - N&V, diarrhoea, cramps

36
Q

5 Step anaphylaxis Tx

A

1) Remove offending agent (e.g. if infusion)

2) IV adrenaline
(500micrograms = 0.5ml 1 in 1000 )

3) Establish airway, give O2, consider Salbutamol

4) IV fluid challenge to correct hypotension
(up to 2L)

5) Chloramphenamine and hydrocortisone can reduce symptom severity and duration

37
Q

Fluid maintenance:

  • Adult
  • Paeds
A

25-30 ml/kg/day of water and. approximately 1 mmol/kg/day of potassium, sodium and chloride.

Fluid resus: 500ml crystaloid in 15 min

38
Q

Fluid maintenance:

  • Adult
  • Paeds
A

25-30 ml/kg/day of water and. approximately 1 mmol/kg/day of potassium, sodium and chloride.

Fluid resus: 500ml crystaloid in 15 min

Paeds hourly = 0-10kg 4 ml per kg, 10-20 2ml/kg/hr after that its 1ml/kg/hour

39
Q

Drugs to stop Pre-op

A

ACEi/ARB: Anaesthetic will drop BP so stop 24 hr before

Warfarin: if Af use LMWH bridging protocol

Clopidogrel: stop 5d before

40
Q

For Insulin dependant diabetics pre-surgery

A

Don’t starve

Give variable rate insulin infusion

41
Q

What makes up a difficult airway

A

Anatomically: small mouth, small chin, big neck, beard

Mechanical: mouth opening, neck mobility

Dentition: dentures

42
Q

Pre-op prediction of difficult airway

A

Mallampati

Thyromental distance (under 6.5cm = difficult)

Upper cervical spine extension

43
Q

The anaesthetic triad

A

Unconsciousness

Analgesia (local or systemic)

Muscle relaxation

44
Q

3 Phases of anaesthesia

A

Induction (normally IV)
Maintenance (IV e.g. propofol and remifentanil infusion or inhaled e.g. volatiles)
Reversal

45
Q

Opioids used in anaesthesia

A

Remifentanil
Alfentanyl
Fentanyl
Morphine (nausea)

All risk respiratory depression

46
Q

What GCs needs airway control

A

8

47
Q

Airway manoeuvres

Airways

A

Head tilt, Chin lift, Jaw thrust

Guedel (Oropharyngeal), Nasopharyngeal (Beware skull base fracture), Supraglottic (LMA), ET tube

48
Q

When is Muscle relaxant needed

A

Intubation: relax tracheal opening

Relax skeletal muscles for surgery

49
Q

Local anaesthetic action

A

Unionised LA enters cell

LA becomes ionised and blocks Na channel

50
Q

Types of use for NA

A

Local wound/area
Peripheral nerve block
Plexus block
Spidural/Spinal block

51
Q

Lidocaine Vs Bupivocaine

Onset
Duration
Use

A

Onset:
L - immediate
B - 10 mins

Duration:
L - 15 mins
B - 12 hrs analgesia

Use:
L - small procedures, lacerations, chest drain
B - Regional blocks

52
Q

Advantages of regional anaesthesia

A

Avoid GA
Can stake awake
Avoid airway issues
Less N&V

53
Q

Spinal Vs Epidural

A

Spinal through ligaments and dura. Local anaesthetic bolus lasts 2 hours

Epidural - through ligaments, sit on top of dura. Catheter and infusion of LA

Both block from below highest nerve root affected

54
Q

Types of muscle relaxants

A

Depolarising
- Suxamethonium (depolarises and blocks depolarisation)

Non-depolarising

  • Atracruium, rocurnium
  • Competitive inhibition of ACh at nicotinic receptors
55
Q

Reversal of muscle relaxants

A

Neostigmine (inc Each by blocking ACh esterase)

56
Q

BP formula

A

CO X systemic vascular resistance

CO = HR X SV

57
Q

Why older have faster HR

A

Lower vagal tone.

Vagus is PSNS

58
Q

Drugs to inc HR in surgery

A

Block ACh (Atropine)

Stimulate Beta-adrenoreceptors (Dobutamine) = inc HR and contractility

59
Q

Drugs to give if BP too low

A

Stim alpha adrenoreceptors

Ephidrine and adrenaline
- added befit of also inc HR
Alpha nd beta stimulation

60
Q

WHO pain ladder

  • Step 1
  • Step 2
  • Step 3
A

1) aspirin, para, NSAIDs
2) Codeine ±non-opioid
3) Morphine ± non-opioid

61
Q

Paracetamol caution and reversal

A

Liver failure in OD (Glutathione depletion)

N-acetyl-cysteine

62
Q

NSAIDs mechanism

A

COX inhibitors (irreversible)

COX usually converts Arachidonic acid into PGs = inflammation, rubor, dolor

63
Q

SE of NSAIDs

A

Peptic ulcers (prostaglandins key in mucus secretion)

AKI: Pre-renal and infrarenal (nephrotoxic)

Bleeding

64
Q

Opioids SE

A

CNS: sedation, Miosis (constriction)

CVS: Bradycardia, Hypotension

Resp: Bradypnoea, apnoea

GI: N&V, constipation

Urinary retention

65
Q

Opioids mechanism

A

Pre and post synaptic modulation via MU receptors

66
Q

Weak opioid and strong opioid examples

A

Weak:

  • Codeine (PO/IM) = prodrug connected to morphine
  • Tramadol

Strong:
- Morphine, oxycodone, Methadone, Buprenorphine

67
Q

Calories per Kg needed

A

20

68
Q

Crystaloids Vs colloids

A

Crystaloids have ions or small molecules which dissolve in water

Colloids have large insoluble molecules retained within plasma. Can be natural (blood albumin) or synthetic (starch, gelatin)

69
Q

O2 sats aims

A

94-98%

If T2RF 88-92% (don’t want to remove hypoxic drive)

70
Q

E.G of non-invasive ventilation

A

CPAP (T1RF)

BiPAP (T2RF - keeps airways open on expiration to allow CO2 clearance)

Venturi mask

71
Q

Invasive ventilation E.G

A

ET tube, Tracheostomy

72
Q

Complications invasive ventilation

A

Ventilator assoc pneumonia

Vent assoc lung injury

Oxygen toxicity

73
Q

Indications for intubation

A

Paralysis

Long surgery

Surgery with: Lung disease, Obese

Low GCS