Anaemia

Question 1

What is anaemia?

Answer 1

• Reduction in the amount of haemoglobin in a given volume of blood below what would be expected in comparison with a healthy subject of the same age and gender
• Hb is reduced
• RBC and Hct/PCV are usually also reduced

NOTE: occasionally it results from an increase in the volume of plasma rather than a decrease in the amount of haemoglobin

Question 2

In a healthy person, anaemia resulting from an increase in plasma volume cannot persist because…?

Answer 2

The excess fluid in the circulation is excreted
For practical purposes, anaemia can therefore be regarded as resulting from a decrease of the absolute amount of haemoglobin in the circulation

Question 3

What are the mechanisms of anaemia?

Answer 3

Slide 6

Question 4

What are the classifications of anaemia (based on cell lsize)?

Answer 4

Slide 10

Question 5

What are the common causes of microcytic anaemia?

Answer 5

Slide 11

Question 6

Macrocytic anaemias usually result from…?

Answer 6

Slide 12

Slide 16

Question 7

Whta is megaloblastic erythropoiesis?

Answer 7

Slide 13

Question 8

What is a megaloblast?

Answer 8

Slide 14

Question 9

What are the common causes of macrocytic anaemia?

Answer 9

Slide 17, 18

Question 10

What are the mechanisms of normocytic normochromic anaemia?

Answer 10

Slide 19

Question 11

What are the causes of normochromic anaemia?

Answer 11

Slide 20

Question 12

What is haemolytic anaemia?

Answer 12

Slide 21

Question 13

Haemolytic anaemia can also be classified as…?

Answer 13

Inherited or acquired

Intravascular or extravascular

Question 14

Inherited haemolytic anaemia can result from…?

Answer 14

Slide 22

Question 15

Acquired haemolytic anaemia usually results from…?

Answer 15

Slide 22

Question 16

Extrinsic factors can interact with red cells that have an intrinsic abnormality
CLOZE

Answer 16

….

Question 17

Intravascular haemolysis occurs if there is…?

Answer 17

Slide 23

Question 18

Extravascular haemolysis occurs when…?|

Answer 18

Slide 23

Question 19

Often haemolysis is partly intravascular and partly extravascular
CLOZE

Answer 19

…..

Question 20

What are the differences between inherited and acquired haemolytic anaemia?

Answer 20

Slide 26

Question 21

When should you expect haemolyticanaemia?

Answer 21

Slide 28

Question 22

Give examples of inherited haemolytic anaemia

Answer 22

Slide 33

Question 23

Give some examples of acquired haemolytic anaemia

Answer 23

Slide 34

Question 24

What is hereditary spherocytosis?

Answer 24

Slide 35-38

Question 25

How is hereditary spherocytosis treated?

Answer 25

Slide 39

Question 26

What is glucose-6-phosphate dehydrogenase (G6PD) deficinecy?

Answer 26

Slide 40-50

Question 27

Autoimmune haemolytic anaemia results from…?

Answer 27

Slide 51-54

Question 28

How is autoimmune haemolytic anaemia diagnosed?

Answer 28

Slide 55

Question 29

How is autoimmune haemolytic anaemia treated?

Answer 29

Slide 56

Question 30

How is microangiopathic haemolytic anaemia treated?

Answer 30

Slide 57

Question 31

A microcytic anaemia is likely to be due to…?

Slide 58 SBA

Answer 31

…..

Question 32

Polycythaemia in a patient seeing his general practictionerin london because he has noticed his urine is red is most likely to be due to…?
Slide 59 SBA

Answer 32

…..