Anaemia Flashcards
1
Q
Low on both B12 and folate, which is important to treat first and why?
A
Treat B12 first before raising folate, or B12 neuropathy gets worse
2
Q
Causes of microcytic anaemia?
A
Iron deficiency
Thalassemia
3
Q
Blood tests to rule out/in iron deficiency?
A
Serum iron, ferritin and TIBC
low, low and high
4
Q
Causes of normocytic anaemia?
A
Leukaemias
Other bone marrow failure
Haemolytic anaemias (high reticulocyte)
Haemorrhage
5
Q
Causes of macrocytic anaemia?
A
B12/folate def Drugs Alcohol Myelodysplastic syndrome Liver disease
6
Q
Symptoms of anaemia
A
Exercise dyspnoea
Pallor
7
Q
Ix for anaemia
A
- FBC
- Peripheral blood smear (to check if megalobastic or not)
- Serum folate, B12
- Iron studies
- Reticulocyte count
8
Q
Causes of b12 def
A
Coeliac Crohn's Pernicious anaemia Thyroid Gastric bypass Abx use Vegan Alcohol
9
Q
Causes of folate def
A
Coeliac Crohn's Gastric bypass Pregnancy Alcohol abuse Diet
