Amygdala PTSD Flashcards
Kluver- Bucy Syndrome
loss of behavioral inhibition, and feeding
docile
reduced fear
agydala lesion
Basolateral Division of Amygdala
input from sensory cortex and hippocampus
involved in anxiety/fear
behavioal recognition
projects to central division
Central Division of Amygdala
input from basolateral division
regulate anxiety/fear, fight or flight
projects to septum, hypothalamus, brainstem, spinal cord
Hyperphagia
loss of inhibition of feeding
loss of amygdala interaction with hypothalamus
PTSD
from event of serious injury
hypervigiliance
insomnia, flashbacks, wihdrawal
Yohimbine
blocks NE receptor
results in elevated fear response
Treatment of PTSD
SSRIs- selective serotonin reuptake inhibitor
antidepressants
Dorsal Anterior Cingulate Cortex
dACC
promotes fear reactions through amygdala activation
hyperactive in PTSD
Peri-genual Cortex
reduces fear by inhibiting amygdala
hypoactive in PTSD
Cortical Region of Amygdala
Primary olfactory region
Possible role in reproductive behavior via projections to septum and hypothalamus