Amiodarone

Question 1

AMIODARONE:

Class / Mechanism:

Answer 1

ACTION: Antiarrhythmic

• Antiarrhythmic that slows conduction and lengthens the cardiac action potential resulting in suppression of ventricular and supraventricular tachycardias.

Question 2

AMIODARONE:

Indications:

Answer 2

INDICATIONS:

• Wide complex ventricular tachycardia with a regular rhythm

• Adult
  
  • Stable w/ regular rhythm
• Ped
  
  • If stable (with pulses and good perfusion)
  • Consult with Base Physician for Amiodarone
• Adult: Pulseless VT/VF / PED: Pulseless Arrest VT/VF
  
  • After 3rd SHOCK

Question 3

AMIODARONE:

CONTRAINDICATIONS:

Answer 3

CONTRAINDICATIONS:

• Sinus node dysfunction or sinus bradycardia
• 2nd or 3rd degree block
• Known hypersensitivity from past exposur

Question 4

AMIODARONE:

ADULT DOSE/ROUTE:

Answer 4

ADULT DOSE/ROUTE:

• Pulseless VT/VF:
  
  • After 3rd SHOCK
    
    • +Amiodarone 300 mg IV/ IO
      
      • Repeat Epinephrine 0.1mg/mL;
        
        • 1 mg IV/ IO Q 10 minutes, up to 3 doses
    • Amiodarone 150 mg IV/ IO
      
      • 3-5 minutes after 1st dose
• Wide complex ventricular tachycardia with a regular rhythm
  
  • Drip: 150 mg in 100 ml D5W give over 10 mins. (= 100 gtts/min with 10 gtts/ml tubing)

Question 5

AMIODARONE:

PEDIATRIC DOSE/ROUTE:

Answer 5

PEDIATRIC DOSE/ROUTE:

• DRIP:
  
  • 5 mg/kg

Mix in 100mL D5W Give over 20-60 min. (50 to 17 gtts/min.) 10 gtts/ml tubing

• VF or pulseless VT only:
  
  • 5 mg/kg IVP or IO bolus.
• Wide Complex Tachycardia:
  
  • Consult with Base Physician for Amiodarone
    5 mg/kg IV/IO. Over 20-60 minutes

(Maximum dose 300 mg)

Question 6

AMIODARONE:

How Supplied:

Answer 6

Supplied:

• 150 mg in 3 mL