Albuterol Sulfate

Question 1

Albuterol

• Trade Name(s):

Answer 1

Albuterol

• Trade Name(s):
  
  • Ventolin®
  • Proventil®

Question 2

Albuterol

• Class:

Answer 2

Albuterol

• Class:
  
  • Short-acting beta2 agonist

Question 3

Albuterol

• Mechanism of Action

Answer 3

Albuterol

• Mechanism of Action:
  
  • Relaxing the smooth muscles of the airways. It activates the beta2-adrenergic receptors in the lungs, which begins a cascade of actions that result in bronchodilation.

Question 4

Albuterol

• Indications:

Answer 4

Albuterol

• Indications:
  
  • ANAPHYLAXIS
    
    • after epi w/ no signs of shock
  • RESPIRATORY DISTRESS
    • Adult
      
      • Mild: Albuterol only by nebulizer
      • moderate to severe: Albuterol + Ipratropium by nebulizer, BVM or CPAP
    • Ped:
      
      • Mild: via handheld nebulizer, mask, BVM
      • moderate to severe: Albuterol + Ipratropium by nebulizer or BVM
  • CRUSH INJURY SYNDROME
    
    • 10-20mg via neb.
  • HYPERKALEMIA with significant ECG changes

Question 5

Albuterol

• ContraIndications:

Answer 5

Albuterol

• ContraIndications:
  
  • Acute tachydysrhythmias, known hypersensitivity.

Question 6

Albuterol

• Adult dosing:

Answer 6

Albuterol

• Adult dosing:
  
  • mild respiratory distress
    
    • 5 mg in 6 mL NS via hand-held nebulizer
  • Moderate-severe:
    
    • 5 mg in 6 mL NS
      + Ipratropium via hand-held nebulizer, mask, or BVM or CPAP
  • CRUSH INJURY SYNDROME

10-20mg via neb.

* HYPERKALEMIA with significant ECG changes
    * 10-20mg via neb. or BVM

Question 7

Albuterol

• Pediatric Dosing:

Answer 7

Albuterol

• Pediatric Dosing:
  
  • Respiratory Distress / wheezing
    • ​Mild:
      
      • 5 mg in 6 ml NS
        via hand-held nebulizer, mask or BVM
        May repeat x1
    • Moderate-Severe:
      • 5 mg in 6 ml NS and Ipratropium
        500 mcg (2.5 ml)
        by nebulizer or via BVM

Question 8

Albuterol

• How Supplied:

Answer 8

Albuterol

• How Supplied:
  
  • 2.5mg/3mL NS

Question 9

Albuterol

• Side/Adverse effects:

Answer 9

Albuterol

• Side/Adverse effects:
  
  • Tachydysrhythmia, palpitations, tremors, dizziness, nervousness, nausea, headache, insomnia.

Question 10

Albuterol:

• Onset/Duration/Pharmacokinetics:

Answer 10

Albuterol:

• Onset/Duration/Pharmacokinetics:
  
  • 5-15 minutes/3-4 hours/ t1/2 = 3-5 hours

Question 11

Albuterol

• Pregnancy safety:

Answer 11

Albuterol

• Pregnancy safety:
  
  • C. Not for use in nursing.

Question 12

Albuterol:

• Notes:

Answer 12

Albuterol:

• Notes:
  
  • If inadequate tidal volume, use PPV with inline nebulizer.