Aminoglycosides Flashcards
1
Q
Characteristics of Aminogycosides
A
cheap, high antibacterial activity, very polar and poor lipid soluble, active transport across cells (oxygen)
2
Q
adverse effects
A
neurotoxicity/ neuromuscular junction blockage/ nephrotoxicity
3
Q
Absorption of Aminoglycosides
A
Oral and injection
4
Q
Distribution of Aminoglycosides
A
ECF, lungs, placenta
5
Q
storage of Aminoglycosides
A
Kidney, ears
6
Q
metabolism of Aminoglycosides
A
kidney
7
Q
metabolism of Aminoglycosides
A
kidney
8
Q
Excretion of Aminoglycosides
A
urine and feces