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BioChem 1 > Amino Acids > Flashcards

Amino Acids Flashcards

1
Q

What are the nonpolar, aliphatic amino acids? (7)

A

Glycine, Alanine, Valine, Leucine, Isoleucine, Proline, Methionine

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2
Q

What is the three letter and one letter abbreviation of Glycine?

A

Gly (G)

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3
Q

What is the three letter and one letter abbreviation of Alanine?

A

Ala (A)

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4
Q

What is the three letter and one letter abbreviation of Valine?

A

Val (V)

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5
Q

What is the three letter and one letter abbreviation of Leucine?

A

Leu (L)

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6
Q

What is the three letter and one letter abbreviation of Isoleucine?

A

Ile (I)

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7
Q

What is the three letter and one letter abbreviation of Proline?

A

Pro (P)

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8
Q

What is the three letter and one letter abbreviation of Methionine?

A

Met (M)

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9
Q

Which amino acid has the smallest side chain and is the most flexible?

A

Glycine

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10
Q

What is the only achiral amino acid?

A

Glycine

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11
Q

What are the aromatic amino acids? (3)

A

Phenylalanine, Tyrosine, Tryptophan

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12
Q

What is special about the aromatic amino acids?

A

There ability to absorb light at ultraviolet range; florescent

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13
Q

What is the three letter and one letter abbreviation of Phenylalanine?

A

Phe (F)

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14
Q

What is the three letter and one letter abbreviation of Tyrosine?

A

Tyr (Y)

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15
Q

What is the three letter and one letter abbreviation of Tyrosine?

A

Tyr (Y)

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16
Q

What is the three letter and one letter abbreviation of Tryptophan?

A

Trp (W)

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17
Q

Which amino acid contains a phenol groups and when is it ionizable?

A

Tyrosine; pKa= 10.1

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18
Q

What are the basic amino acids with positively charged amino acid side chains? (3)

A

Lysine, Arginine, Histidine

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19
Q

What is the three letter and one letter abbreviation of Lysine?

A

Lys (K)

20
Q

What are the three letter and one letter abbreviation of Arginine?

A

Arg (R)

21
Q

What are the three letter and one letter abbreviations of Histidine?

A

His (H)

22
Q

Which basic amino acid has a butyl side chain and when is it ionizable?

A

Lysine; pKa= 10.5

23
Q

Which basic amino acid has a guanidino groups at end of the side chain and when is it ionizable?

A

Arginine; pKa= 12.5

24
Q

Which basic amino acid has an imidazole functional group and when is it ionizable?

A

Histidine; pKa= 6.0

25
Q

What are the acidic amino acids with negatively charged amino acid sidechains? (2)

A

Aspartate, Glutamate

26
Q

What is the three letter and one letter abbreviation of Aspartate?

A

Asp (D)

27
Q

What is the three letter and one letter abbreviation of Glutamate?

A

Glu (E)

28
Q

Which acidic amino acid has a side chain containing a carboxylic acid functional group ionizable at pKa= 3.9?

A

Aspartate

29
Q

Which acidic amino acid contains a side chain with a carboxylic acid functional group ionizable at pKa= 4.1?

A

Glutamate

30
Q

What are the polar, uncharged amino acids? (5)

A

Asparagine, Glutamine, Serine, Threonine, Cysteine

31
Q

What is the three letter and one letter abbreviation of Asparagine?

A

Asn (N)

32
Q

What is the three letter and one letter abbreviation of Glutamine?

A

Gln (Q)

33
Q

What is the three letter and one letter abbreviation of Serine?

A

Ser (S)

34
Q

What is the three letter and one letter abbreviation of Threonine?

A

Thr (T)

35
Q

What is the three letter and one letter abbreviation of Cysteine?

A

Cys (C)

36
Q

Which polar, uncharged amino acid has a thiol/sulfhydryl side chain and when is it ionizable?

A

Cysteine; pKa= 8.3

37
Q

Which aromatic amino acid contains the indole side chain?

A

Tryptophan

38
Q

Which amino acid has a thioether?

A

Methionine

39
Q

Which amino acid has an amide?

A

Asparagine

40
Q

What type of stereochemistry do amino acids in proteins have?

A

L-stereochem

41
Q

What is the configuration of the amino acids? (R/S)

A

18/20 are S configuration

42
Q

Which two amino acids are not S configuration? Why?

A

Glycine- achiral
Cysteine- R configuration; CH2SH has priority over COOH

43
Q

How are peptide bonds formed?

A

Through the elimination of water

44
Q

What is N-terminus?

A

Amino terminus- residue with free amino group

45
Q

What is C-terminus?

A

Carboxyl terminus- residue with free carboxylate

46
Q

How to name peptides?

A

beginning at the amino terminal end; dropping -ine and adding -yl.
Ex: serylglycyltryosylalanylleucine; Ser-Gly-Try-Ala-Leu; SGYAL

BioChem 1 (4 decks)

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